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An Alport syndrome boy with Van Wyk-Grumbach syndrome induced by prolonged untreated congenital hypothyroidism

Lee SJ, Moon JE, Lee GM, Cho MH, Ko CW

Alport syndrome (AS) is a rare genetic disorder that causes progressive nephritis and is more common among males. Studies have reported an association between thyroid antibodies and hypothyroidism in patients...
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Clinical, endocrinological, and molecular features of four Korean cases of cytochrome P450 oxidoreductase deficiency

Lee Y, Choi JH, Oh A, Kim GH, Park SH, Moon JE, Ko CW, Cheon CK, Yoo HW

Purpose: Cytochrome P450 oxidoreductase (POR) deficiency is a rare autosomal recessive disorder caused by mutations in the POR gene encoding an electron donor for all microsomal P450 enzymes. It is...
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De novo a novel variant of CaSR gene in a neonate with congenital hypoparathyroidism

Moon JE, Lee SJ, Park SH, Kim J, Jin DK, Ko CW

Autosomal-dominant hypocalcemia with hypercalciuria (ADHH) is a genetic disease characterized by hypoparathyroidism with hypercalciuria. Most patients with ADHH have calcium-sensing receptor (CaSR) gene mutations. The CaSR gene controls parathyroid secretions,...
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Aesthetic restoration n patients with unaesthetic maxillary anterior teeth using double scan : A case report

Ko CW, Kim MJ, Yang HS, Park SW, Park C, Yun KD

In case of the treatment of maxillary anterior teeth, it should be taken into account the proper morphology, arrangement and color satisfying patient's esthetic demands. For this purpose, facial composition,...
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Complete denture rehabilitation of edentulous patient with severe alveolar bone resorption using mandibular suction denture with closed mouth technique: a clinical report

Ko CW, Min B, Yang HS, Lim HP, Yun K, Shin JH

When it comes to treat patient with loss of vestibule, conventional denture impression have limitation which can cause problems of excessive border extension. Suction denture with closed mouth technique which...
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Neutral zone approach and external impression for rehabilitation of severely atrophic maxillary and mandibular ridges: a case report

Jo Y, Ko CW, Park SW, Yun KD, Park C, Lim HP

In order to produce a stable denture for severe alveolar bone loss area, it is not only important that .0a suitable occlusion is established but also to consider compatibility with...
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Severe recurrent nocturnal hypoglycemia during chemotherapy with 6-mercaptopurine in a child with acute lymphoblastic leukemia

Cho EM, Moon JE, Lee SJ, Ko CW

Various endocrine dysfunctions occur during chemotherapy, including hypoglycemia. However, reports of hypoglycemia associated with 6-mercaptopurine (6-MP) are rare. Herein, we report an 8-year-old boy with severe symptomatic hypoglycemia likely due...
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Delayed diagnosis of pituitary stalk interruption syndrome with severe recurrent hyponatremia caused by adrenal insufficiency

Jang KM, Ko CW

Pituitary stalk interruption syndrome (PSIS) involves the occurrence of a thin or absent pituitary stalk, hypoplasia of the adenohypophysis, and ectopic neurohypophysis. Diagnosis is confirmed using magnetic resonance imaging. Patients...
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Initial steroid regimen in idiopathic nephrotic syndrome can be shortened based on duration to first remission

Baek HS, Park KS, Kang HG, Ko CW, Cho MH

PURPOSE: The use of a 12-week steroid regimen (long-term therapy, LT) for the first episode of idiopathic nephrotic syndrome (NS) reportedly induces a more sustained remission and lower relapse rate...
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Comparison of the Therapeutic Efficacy of Methylprednisolone Pulse Therapy and Oral Steroid Therapy in Children with IgA Nephropathy and HSP Nephritis Combined with Proteinuria

Ahn JY, Moon JE, Hwang YJ, Choi BS, Ko CW, Cho MH

  • KMID: 2196564
  • J Korean Soc Pediatr Nephrol.
  • 2014 Apr;18(1):24-28.
PURPOSE: The purpose of this study was to assess the therapeutic efficacy of methylprednisolone pulse therapy in children with IgA nephropathy and Henoch-Schonlein Purpura (HSP) nephritis combined with proteinuria. METHODS: We...
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The Risk Factors and Quality of Life in Patients with Overlapping Functional Dyspepsia or Peptic Ulcer Disease with Gastroesophageal Reflux Disease

Lee SW, Lee TY, Lien HC, Yeh HZ, Chang CS, Ko CW

  • KMID: 1774543
  • Gut Liver.
  • 2014 Mar;8(2):160-164.
BACKGROUND/AIMS: Gastroesophageal reflux disease (GERD), functional dyspepsia (FD), and peptic ulcer disease (PUD) impact the daily lives of affected individuals. The aim of this study was to compare the risk...
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Efficacy of Short-Term Growth Hormone Treatment in Prepubertal Children with Idiopathic Short Stature

Kim HS, Yang SW, Yoo HW, Suh BK, Ko CW, Chung WY, Lee KH, Hwang JS, Ji HJ, Ahn H, Kim DH

PURPOSE: It has been reported that daily recombinant human growth hormone (GH) treatment showed beneficial effects on growth in prepubertal children with idiopathic short stature (ISS). The present study aimed...
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Various endocrine disorders in children with t(13;14)(q10;q10) Robertsonian translocation

Choi BH, Kim UH, Lee KS, Ko CW

PURPOSE: 45,XY,t(13;14)(q10;q10) karyotype can suggest infertility associated with more or less severe oligospermia in male adults. In addition, 45,XX,t(13;14)(q10;q10) karyotype carries reproductive risks such as miscarriage or infertility in female...
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Clinical manifestations of IgA nephropathy combined with thin glomerular basement membrane nephropathy in children

Hwang YJ, Kim DS, Ko CW, Cho MH, Park TI

  • KMID: 2224304
  • Kidney Res Clin Pract.
  • 2013 Sep;32(3):111-114.
BACKGROUND: Immunoglobulin A nephropathy (IgAN) and thin glomerular basement membrane nephropathy (TBMN) are the most common causes of persistent hematuria during childhood. The objective of this study is to determine...
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Polyclonal gammopathy related to renal bleeding in a peritoneal dialysis patient

Cho EM, Moon HH, Hwang YJ, Lee SJ, Ko CW, Cho MH

Polyclonal gammopathy represents the diffuse activation of B cells and is usually related to inflammation or immune-related diseases. However, the mechanisms leading to polyclonal gammopathy are essentially speculative. Generally, infectious,...
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Changes of antithroglobulin antibody in children with congenital hypothyroidism

Cho EM, Kim UH, Choi BH, Ko CW

PURPOSE: It has been reported that antithroglobulin (anti-TG) antibody is increased in the sera of both children with transient congenital hypothyroidism and their mothers. And transplacental transport of thyroid autoantibody...
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A Single-Arm, Phase III Study to Assess Efficacy and Safety after 6-Month-Treatment of Eutropin(TM) Inj. (Recombinant Human Growth Hormone) in Prepubertal Children with Short Stature due to Small for Gestational Age

Lee KH, Lee BC, Ko CW, Jin DK, Yang SW, Yoo HW, Chung WY, Kim DH, Suh BK

PURPOSE: Recombinant human growth hormone is an effective therapy for short-statured children born small for their gestational age (SGA). This single-arm, multicenter, phase III clinical study of such children was...
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Clinical Usefulness of Ambulatory Blood Pressure Monitoring in Children and Adolescents

Hwang YJ, Park HJ, Yang EA, Cho MH, Ko CW, Yang DH, Hwang HH

  • KMID: 2196709
  • J Korean Soc Pediatr Nephrol.
  • 2011 Oct;15(2):154-162.
PURPOSE: With increasing prevalence of hypertension (HTN) in children and adolescent, pediatricians have become more interested in blood pressure (BP) measurements. The ambulatory blood pressure monitoring (ABPM) is known to...
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Methylprednisolone Pulse Therapy for Focal Segmental Glomerulosclerosis in Children: with the Mendoza Protocol

Yang EA, Park HJ, Cho MH, Ko CW

  • KMID: 2307151
  • Korean J Nephrol.
  • 2011 Jan;30(1):18-25.
PURPOSE: The clinical characteristics and pathological findings of patients with focal segmental glomerulosclerosis (FSGS) receiving methylprednisolone pulse therapy (MP pulse therapy) according to the Mendoza protocol were studied to evaluate...
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Prevention of Recurrent FSGS with Cyclosporine and Plasmapheresis Prior to Renal Transplantation

Yang EA, Park HM, Cho MH, Ko CW, Kim HK, Huh S

  • KMID: 2322028
  • J Korean Soc Pediatr Nephrol.
  • 2010 Apr;14(1):100-104.
We report on two children with a high risk of recurrent focal segmental glomerulosclerosis (FSGS) after renal transplantation that could be effectively prevented by prophylactic administration of cyclosporine combined with...
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