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Spontaneous Regression of a Large Hepatocellular Carcinoma with Multiple Lung Metastases

Saito T, Naito M, Matsumura , Kita H, Kanno T, Nakada Y, Hamano M, Chiba M, Maeda K, Michida T, Ito T

A 75-year-old Japanese man with chronic hepatitis C was found to have a large liver tumor and multiple nodules in the bilateral lungs. We diagnosed the tumor as hepatocellular carcinoma...
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Activation of Eosinophils with Airborne Fungi

Shin SH, Kim JK, Kita H

  • KMID: 2276174
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Jun;47(6):549-553.
BACKGROUND AND OBJECTIVES: Allergic fungal sinusitis is characterized by allergic mucin which includes eosinophils and fungal hyphae. But we don't know why eosinophils are accumulated at the nasal secretion and...
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Degranulation of human eosinophils induced by Paragonimus westermani-secreted protease

Shin MH, Chung YB, Kita H

Eosinophil degranulation is considered to be a key effector function for the killing of helminthic worms and tissue inflammation at worm-infected lesion sites. However, relatively little data are available with...
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Role of IL-5 and eotaxin in airway eosinophilic inflammation

Kim CK, Kita H, Yu JH, Koh YY

  • KMID: 2285825
  • J Asthma Allergy Clin Immunol.
  • 2004 Mar;24(1):127-136.
BACKGROUND: IL-5 and eotaxin are the most important cytokines/chemokines responsible for regulating eosinophil locomotion. OBJECTIVE: We investigated the role of IL-5 and eotaxin in airway eosinophilic inflammation in patients with chronic...
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A 27 kDa Cysteine Protease Secreted by Newly Excysted Paragonimus westermani Metacercariae Induces Superoxide Anion Production and Degranulation of Human Eosinophils

Chung YB, Kita H, Shin MH

Eosinophil degranulation plays a crucial role in tissue inflammatory reactions associated with helminth parasitic nfections and allergic diseases. Paragonimus westermani, a lung fluke causing human paragonimiasis, secretes a large amount...
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Increases in IFN-gamma during the Chronic Asymptomatic Phase in Patients with Asthma

  • KMID: 2234222
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Dec;24(4):377-384.
BACKGROUND AND OBJECTIVE: Previous studies, during acute asthma exacerbations, have suggested roles for the Th2 cytokines in promoting airway inflammation in asthma patients. We assessed mediators of airway inflammation during...
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