- The Mechanism of Anti-Epileptogenesis by Levetiracetam Treatment is Similar to the Spontaneous Recovery of Idiopathic Generalized Epilepsy during Adolescence
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Kikuyama H, Hanaoka T, Kanazawa T, Yoshida Y, Mizuno T, Toyoda H, Yoneda H
- KMID: 2402413
- Psychiatry Investig.
- 2017 Nov;14(6):844-850.
- doi: 10.4306/pi.2017.14.6.844
OBJECTIVE: The anti-epileptogenic drug levetiracetam has anticonvulsant and anti-epileptogenesis effects. Synergy between cell death and inflammation can lead to increased levels of apoptosis inhibitory factors and brain-derived neurotrophic factor, aberrant... -
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- Increases in iPS Transcription Factor (Oct4, Sox2, c-Myc, and Klf4) Gene Expression after Modified Electroconvulsive Therapy
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Nishiguchi M, Kikuyama H, Kanazawa T, Tsutsumi A, Kaneko T, Uenishi H, Kawabata Y, Kawashige , Koh J, Yoneda H
- KMID: 2391826
- Psychiatry Investig.
- 2015 Oct;12(4):532-537.
- doi: 10.4306/pi.2015.12.4.532
OBJECTIVE: Electroconvulsive therapy (ECT) is a reasonable option for intractable depression or schizophrenia, but a mechanism of action has not been established. One credible hypothesis is related to neural plasticity.... -
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- An Association Study of the Signal Transducer and Activator of Transcription 6 Gene With Periodic Psychosis
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Kawashige , Kanazawa T, Tsutsumi A, Kikuyama H, Uenishi H, Koh J, Yoneda H
- KMID: 2315784
- Psychiatry Investig.
- 2008 Mar;5(1):41-44.
OBJECTIVE: Recent molecular and genetic investigations have suggested that the current nosology for major psychiatric disorders, based on the "two-entities-principal" is not accurate with respect to clinical observations; patient groups... -
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- Association between Medication Adherence and Duration of Outpatient Treatment in Patients with Schizophrenia
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Tarutani S, Kikuyama H, Ohta M, Kanazawa T, Okamura T, Yoneda H
- KMID: 2344739
- Psychiatry Investig.
- 2016 Jul;13(4):413-419.
- doi: 10.4306/pi.2016.13.4.413
OBJECTIVE: Medication adherence is important in the treatment of schizophrenia, and critical periods during treatment may be associated with relapse. However, the relationship between adherence and duration of outpatient treatment... -
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- Genetic Polymorphisms in Dopamine- and Serotonin-Related Genes and Treatment Responses to Risperidone and Perospirone
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Tsutsumi A, Kanazawa T, Kikuyama H, Okugawa G, Uenishi H, Miyamoto T, Matsumoto , Koh J, Shinosaki , Kishimoto , Yoneda H, Kinoshita
- KMID: 2315841
- Psychiatry Investig.
- 2009 Sep;6(3):222-225.
We investigated the possible association between genetic polymorphisms in the dopamine receptor and serotonin transporter genes and the responses of schizophrenic patients treated with either risperidone or perospirone. The subjects... -
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