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Expression of progesterone receptor in human keratinocytes

Im S, Lee ES, Kim W, Song J, Kim J, Lee M, Kang WH

Despite the various responses of human skin to female sex hormones, cellular and subcellular targets and the mechanisms of action of estrogen and progesterone in human skin are not well...
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Expression Patterns of Cytokeratins in Cholesteatomas: Evidence of Increased Migration and Proliferation

Kim HJ, Tinling SP, Chole RA

Aural cholesteatoma is characterized by invading squamous epithelia with altered growth properties. Cytokeratin (CK) expression is affected in epidermal proliferative diseases and represents the alterations of keratinocyte proliferation, differentiation, and...
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Calpain inhibitors reduce the cornified cell envelope formation by inhibiting proteolytic processing of transglutaminase 1

Kim SY, Bae CD

  • KMID: 755018
  • Exp Mol Med.
  • 1998 Dec;30(4):257-262.
Calpain I (mu-calpain) and II (m-calpain) are well known calcium-activated neutral cysteine proteases. Many reports have shown that activation of calpain is related to cataract formation, neuronal degeneration, blood clotting, ...
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Bricks and mortar of the epidermal barrier

Nemes Z, Steinert P

  • KMID: 755021
  • Exp Mol Med.
  • 1999 Mar;31(1):5-19.
A specialized tissue type, the keratinizing epithelium, protects terrestrial mammals from water loss and noxious physical, chemical and mechanical insults. This barrier between the body and the environment is constantly maintained by reproduction...
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Low-dose UVB irradiation stimulates matrix metalloproteinase-1 expression via a BLT2-linked pathway in HaCaT cells

Kim C, Ryu HC, Kim JH

Skin exposure to low-dose ultraviolet B (UVB) light up-regulates the expression of matrix metalloproteinase-1 (MMP-1), thus contributing to premature skin aging (photo-aging). Although cyclooxygenase-2 (COX-2) and its product, prostaglandin E2...
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A Novel Synthetic Compound 3-Amino-3-(4-Fluoro-Phenyl)-1H-Quinoline-2,4-Dione (KR22332) Exerts a Radioprotective Effect via the Inhibition of Mitochondrial Dysfunction and Generation of Reactive Oxygen Species

Baek SJ, Chang JW, Park KH, Yang GY, Hwang HS, Koh YW, Jung YS, Kim CH

PURPOSE: Acute side effects of radiation such as oral mucositis are observed in most patients. Although several potential radioprotective agents have been proposed, no effective agent has yet been identified....
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Expression and localization of human papillomavirus type 16 E6 and E7 open reading frame proteins in human epidermal keratinocyte

Kim KH, Yoon DJ, Moon YA, Kim YS

Over 60 different types of human papillomavirus (HPV) have been identified, and they are classified into high and low risk groups based on the risk for malignant progression of HPV...
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