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Purification and biochemical characterization of two novel antigens from Leishmania major promastigotes

Zeinali M, Ardestani , Kariminia

The identification and characterization of antigens that elicit human T cell responses is an important step toward understanding of Leishmania major infection and ultimately in the development of a vaccine....
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Production of nitric oxide by murine macrophages induced by lipophosphoglycan of Leishmania major

Kavoosi G, Ardestani , Kariminia , Tavakoli Z

Protozoan parasites of the genus Leishmania cause a number of important human diseases. One of the key determinants of parasite infectivity and survival is the surface glycoconjugate lipophosphoglycan (LPG). In...
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Identification of novel Leishmania major antigens that elicit IgG2a response in resistant and susceptible mice

Mohammadi , Zeinali M, Ardestani , Kariminia

Experimental murine models with high, intermediate and low levels of genetically based susceptibility to Leishmania major infection reproduce almost entire spectrum of clinical manifestations of the human disease. There are...
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Effects of combined therapy with thalidomide and glucantime on leishmaniasis induced by Leishmania major in BALB/c mice

Solgi G, Kariminia , Abdi K, Darabi M, Ghareghozloo B

For treating Leishmania major infection in BALB/c mice, we used thalidomide in conjunction with glucantime. Groups of mice were challenged with 5 x 10(3) metacyclic promastigotes of L. major subcutaneously....
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