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Generation of Cortical Brain Organoid with Vascularization by Assembling with Vascular Spheroid

Kook MG, Lee SE, Shin N, Kong D, Kim DH, Kim MS, Kang HK, Choi SW, Kang KS

Background and Objectives: Brain organoids have the potential to improve our understanding of brain development and neurological disease. Despite the importance of brain organoids, the effect of vascularization on brain...
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Detection of NDM-1 Metallo-β-Lactamase Genes in Pseudomonas Aeruginosa from Clinical Surveillance Sample: A Case Report and Literature Review

Chang J, Kim S, Kwak YG, Um TH, Cho CR, Kang HK, Song JE

Pseudomonas aeruginosa is an opportunistic pathogen that can be an important nosocomial pathogen. Herein, we report a case of NDM-1-carrying P. aeruginosa isolated from a clinical specimen in Korea. An...
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Renal replacement therapy is an alarm sign of survival outcome in pediatric liver transplantation

Yoo BM, Hong Sy, Hong SK, Ahn YH, Kang HK, Yi N, Suh S, Han ES, Lee KW, Suh KS

Background: Research regarding the impact of renal replacement therapy (RRT) on long-term survival outcome in pediatric liver recipients are scarce. Methods: Two hundred twenty-four patients under 18 years of age who...
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ER71/ETV2 Promotes Hair Regeneration from Chemotherapeutic Drug-Induced Hair Loss by Enhancing Angiogenesis

Lee TJ, Kang HK, Berry JC, Joo HG, Park C, Miller MJ, Choi K

Chemotherapy-induced alopecia and hair loss can be stressful in patients with cancer. The hair grows back, but sometimes the hair tends to stay thin. Therefore, understanding mechanisms regulating hair regeneration...
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Effects of high-flow nasal cannula in patients with mild to moderate hypercapnia: a prospective observational study

Nam KH, Kang HK, Lee SS, Park SH, Kang SW, Hwang JJ, Park SY, Kim WY, Suh HJ, Kim EY, Seo GJ, Koh Y, Hong SB, Huh JW, Lim CM

Background: Evidence for using high-flow nasal cannula (HFNC) in hypercapnia is still limited. Most of the clinical studies had been conducted retrospectively, and there had been conflicting reports for the...
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Erratum to “Utilization of pain and sedation therapy on noninvasive mechanical ventilation in Korean intensive care units: a multi-center prospective observational study”

Kim T, Kim JS, Choi EY, Chang Y, Choi WI, Hwang JJ, Moon JY, Lee K, Kim SW, Kang HK, Sim YS, Park TS, Park SY, Park S, Cho JH, on behalf of the Korean NIV Study Group

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Systemic Lupus Erythematosus Manifested as Pancytopenia during Tuberculosis Treatment

Bae W, Kang J, Park SH, Kang HK, Koo HK, Park HK, Lee SS

A 49-year-old Chinese woman presented to Ilsan Paik Hospital emergency department with fever and general weakness. Chest computed tomography revealed cavity and peribronchial nodules and consolidation in the right upper...
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Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells

Choi YK, Kang JI, Hyun JW, Koh YS, Kang JH, Hyun CG, Yoon KS, Lee KS, Lee CM, Kim TY, Yoo ES, Kang HK

Alopecia is a distressing condition caused by the dysregulation of anagen, catagen, and telogen in the hair cycle. Dermal papilla cells (DPCs) regulate the hair cycle and play important roles...
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Technology trends and applications of deep learning in ultrasonography: image quality enhancement, diagnostic support, and improving workflow efficiency

Yi J, Kang HK, Kwon JH, Kim KS, Park MH, Seong YK, Kim DW, Ahn B, Ha K, Lee J, Hah Z, Bang WC

In this review of the most recent applications of deep learning to ultrasound imaging, the architectures of deep learning networks are briefly explained for the medical imaging applications of classification,...
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Utilization of pain and sedation therapy on noninvasive mechanical ventilation in Korean intensive care units: a multi-center prospective observational study

Kim T, Kim JS, Choi EY, Chang Y, Choi WI, Hwang JJ, Moon JY, Lee K, Kim SW, Kang HK, Sim YS, Park TS, Park SY, Park S, Cho JH, on behalf of the Korean NIV Study Group

Background: The use of sedative drugs may be an important therapeutic intervention during noninvasive ventilation (NIV) in intensive care units (ICUs). The purpose of this study was to assess the...
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Development and Evaluation of Portable Self-Respiratory Training System Using Patch Type Magnetic Sensor

Kang HK, Kim JS, Kim Dw

  • KMID: 2510093
  • Prog Med Phys.
  • 2020 Sep;31(S1):S51.
Purpose: An anatomic motion of organs and tumors due to breathing increases the internal margin in radiation therapy, which increases the uncertainty of treatment. Many studies have been conducted for...
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Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/ β-Catenin Pathway in Dermal Papilla Cells

Kang JI, Choi YK, Koh YS, Hyun JW, Kang JH, Lee KS, Lee CM, Yoo ES, Kang HK

The hair cycle (anagen, catagen, and telogen) is regulated by the interaction between mesenchymal cells and epithelial cells in the hair follicles. The proliferation of dermal papilla cells (DPCs), mesenchymal-derived...
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The Use of Inappropriate Antibiotics in Patients Admitted to Intensive Care Units with Nursing Home–Acquired Pneumonia at a Korean Teaching Hospital

Kim DH, Kim HJ, Koo HW, Bae W, Park SH, Koo HK, Park HK, Lee SS, Kang HK

BACKGROUND: Use of appropriate antibiotics for the treatment of pneumonia is integral in patients admitted to intensive care units (ICUs). Although it is recommended that empirical treatment regimens should be...
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Niacinamide Protects Skin Cells from Oxidative Stress Induced by Particulate Matter

Zhen AX, Piao MJ, Kang KA, Madushan Fernando PDS, Kang HK, Koh YS, Yi JM, Hyun JW

Niacinamide (NIA) is a water-soluble vitamin that is widely used in the treatment of skin diseases. Moreover, NIA displays antioxidant effects and helps repair damaged DNA. Recent studies showed that...
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Purpurogallin Protects Keratinocytes from Damage and Apoptosis Induced by Ultraviolet B Radiation and Particulate Matter 2.5

Zhen AX, Piao MJ, Hyun YJ, Kang KA, Ryu YS, Cho SJ, Kang HK, Koh YS, Ahn MJ, Kim TH, Hyun JW

Purpurogallin, a natural phenol obtained from oak nutgalls, has been shown to possess antioxidant, anticancer, and anti-inflammatory effects. Recently, in addition to ultraviolet B (UVB) radiation that induces cell apoptosis...
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Current Status of Noninvasive Ventilation Use in Korean Intensive Care Units: A Prospective Multicenter Observational Study

Nam H, Cho JH, Choi EY, Chang Y, Choi WI, Hwang JJ, Moon JY, Lee K, Kim SW, Kang HK, Sim YS, Park TS, Park SY, Park S, on behalf of Korean NIV Study Group

BACKGROUND: Data on noninvasive ventilation (NIV) use in intensive care units (ICUs) are very limited in South Korea. METHODS: A prospective observational study was performed in 20 ICUs of university-affiliated hospitals...
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Esculetin Prevents the Induction of Matrix Metalloproteinase-1 by Hydrogen Peroxide in Skin Keratinocytes

Zhen AX, Piao MJ, Kang KA, Fernando P, Kang HK, Koh YS, Hyun JW

BACKGROUND: Reactive oxygen species (ROS) are involved in various cellular diseases. Excessive ROS can cause intracellular oxidative stress, resulting in a calcium imbalance and even aging. In this study, we...
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Prognostic Value of Procalcitonin in Pneumonia among Patients Admitted to Intensive Care Unit.

Kim DH, Jung HW, Kang HK

OBJECTIVES: Pneumonia is one of the leading causes of death in the intensive care unit (ICU). Many biomarkers for predicted prognosis have been suggested; among these, procalcitonin (PCT) is known...
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7,8-Dihydroxyflavone Protects High Glucose-Damaged Neuronal Cells against Oxidative Stress

Cho SJ, Kang KA, Piao MJ, Ryu YS, Fernando P, Zhen AX, Hyun YJ, Ahn MJ, Kang HK, Hyun JW

Oxidative stress is considered a major contributor in the pathogenesis of diabetic neuropathy and in diabetes complications, such as nephropathy and cardiovascular diseases. Diabetic neuropathy, which is the most frequent...
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The Prevalence and Characterization of Cerebral Microbleeds in Young People Having Intracerebral Hemorrhage

Lee YM, Koo HW, Kang HK, Kim JW, Han SR, Yoon SW, Choi CY, Sohn MJ, Lee CH

OBJECTIVE: Cerebral microbleeds (CMBs) are known as the neuroimaging markers of risk in stroke and dementia. Many studies on CMBs in elderly patients with hemorrhagic or ischemic stroke have been...
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