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Advances in Stroke Prevention in 2018

Gurol ME, Kim JS

No abstract available.
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Neuroprotectants in the Era of Reperfusion Therapy

Chamorro A

For decades, numerous pharmacological and non-pharmacological strategies have been evaluated without success to limit the consequences of the ischemic cascade, but more rarely the therapies were explored as add on...
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Alcohol Intake and Risk of Ischemic and Haemorrhagic Stroke: Results from a Mendelian Randomisation Study

Christensen AI, Nordestgaard BG, Tolstrup J

BACKGROUND AND PURPOSE: To test whether alcohol intake, both observational and estimated by genetic instruments, is associated with risk of ischemic and haemorrhagic stroke. METHODS: We used data from the Copenhagen...
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Intracranial Large Artery Disease of Non-Atherosclerotic Origin: Recent Progress and Clinical Implications

Bang OY, Toyoda K, Arenillas , Liu L, Kim JS

Intracranial large artery disease (ILAD) is the major cause of stroke worldwide. With the application of recently introduced diagnostic techniques, the prevalence of non-atherosclerotic ILAD is expected to increase. Herein,...
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Recent Advances in Primary and Secondary Prevention of Atherosclerotic Stroke

Tsivgoulis G, Safouris A, Kim DE, Alexandrov AV

Atherosclerosis is a major cause of ischemic stroke that can be effectively prevented with appropriate lifestyle modifications and control of cardiovascular risk factors. Medical advances in recent years along with...
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Self-Rated Health Status and Risk of Incident Stroke in 0.5 Million Chinese Adults: The China Kadoorie Biobank Study

Dong W, Pan XF, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Wu T, Chen Z, Pan A, Li L, on behalf of the China Kadoorie Biobank Collaborative Group

BACKGROUND AND PURPOSE: Self-rated health (SRH) is a consistent and strong predictor of all-cause and cardiovascular mortality in various populations. However, the associations between SRH measures and risk of first-ever...
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Updates on Prevention of Cardioembolic Strokes

Topcuoglu , Liu L, Kim DE, Gurol ME

Cardiac embolism continues to be a leading etiology of ischemic strokes worldwide. Although pathologies that result in cardioembolism have not changed over the past decade, there have been significant advances...
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Updates on Prevention of Hemorrhagic and Lacunar Strokes

Tsai HH, Kim JS, Jouvent E, Gurol ME

Intracerebral hemorrhage (ICH) and lacunar infarction (LI) are the major acute clinical manifestations of cerebral small vessel diseases (cSVDs). Hypertensive small vessel disease, cerebral amyloid angiopathy, and hereditary causes, such...
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Differences in Therapeutic Responses and Factors Affecting Post-Stroke Depression at a Later Stage According to Baseline Depression

Lee EJ, Kim JS, Chang DI, Park JH, Ahn SH, Cha JK, Heo JH, Sohn SI, Lee BC, Kim DE, Kim HY, Kim S, Kwon DY, Kim J, Seo WK, Lee J, Park SW, Koh SH, Kim JY, Choi-Kwon , Kim MS, Lee JS, the EMOTION Investigators

BACKGROUND AND PURPOSE: The pathophysiology of post-stroke depression (PSD) is complex and may differ according to an individual’s mood immediately after stroke. Here, we compared the therapeutic response and clinical...
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Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden

Duering M, Konieczny , Tiedt S, Baykara E, Tuladhar A, van Leijsen E, Lyrer P, Engelter S, Gesierich , Achmüller M, Barro C, Adam R, Ewers M, Dichgans M, Kuhle J, de Leeuw F, Peters N

BACKGROUND AND PURPOSE: Neurofilament light chain (NfL) is a blood marker for neuroaxonal damage. We assessed the association between serum NfL and cerebral small vessel disease (SVD), which is highly...
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Prevalence and Risk Factors of Cerebral Small Vessel Disease in a Chinese Population-Based Sample

Han F, Zhai FF, Wang Q, Zhou LX, Ni J, Yao M, Li ML, Zhang SY, Cui LY, Jin ZY, Zhu YC

BACKGROUND AND PURPOSE: Epidemiological data of cerebral small vessel disease (CSVD) in the general population of China are lacking. We report on the prevalence of lacunes, white matter hyperintensity (WMH),...
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Nationwide Estimation of Eligibility for Endovascular Thrombectomy Based on the DAWN Trial

Lee KJ, Kim BJ, Kim DE, Ryu WS, Han MK, Kim JT, Choi KH, Cho KH, Cha JK, Kim DH, Nah HW, Park JM, Kang K, Lee SJ, Kim JG, Oh MS, Yu KH, Lee BC, Hong KS, Cho YJ, Park TH, Lee KB, Lee J, Lee JS, Lee J, Bae HJ, Clinical Research Collaboration for Stroke in Korea (CRCS-K) Investigators

No abstract available.
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Susceptibility Vessel Sign in the ASTER Trial: Higher Recanalization Rate and More Favourable Clinical Outcome after First Line Stent Retriever Compared to Contact Aspiration

Bourcier R, Mazighi M, Labreuche , Fahed R, Blanc R, Gory B, Duhamel A, Marnat G, Saleme S, Costalat V, Bracard S, Desal H, Consoli A, Piotin M, Lapergue B, on behalf of the ASTER Trial Investigators

BACKGROUND AND PURPOSE: In the Aspiration vs. Stent Retriever for Successful Revascularization (ASTER) trial, which evaluated contact aspiration (CA) versus stent retriever (SR) use as first-line technique, the impact of...
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