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Mechanisms of the Wnt Pathways as a Potential Target Pathway in Atherosclerosis

Poznyak AV, Sukhorukov VN, Popov MA, Chegodaev YS, Postnov AY, Orekhov AN

The proteins of the Wnt family are involved in a variety of physiological processes by means of several canonical and noncanonical signaling pathways. Wnt signaling has been recently identified as...
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Vegetarian Diet for Cardiovascular Disease Risk Reduction: Cons

Han SN

Numerous studies have reported that adopting a plant-based diet can significantly reduce the risk of cardiovascular diseases (CVDs). Not only does a vegetarian diet help mitigate the risk of these...
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Vegetarian Diets and Cardiovascular Risk Reduction: Pros

Lee SY

There is an ongoing need for public health interventions aimed at further mitigating the risk of cardiovascular disease (CVD) through changes in dietary patterns and other lifestyle habits. Plant-based diets...
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Metformin Reduces the Progression of Atherogenesis by Regulating the Sestrin2-mTOR Pathway in Obese and Diabetic Rats

Sundararajan S, Jayachandran I, Pandey GK, Venkatesan S, Rajagopal A, Gokulakrishnan K, Balasubramanyam M, Mohan V, Manickam N

Objective: In previous research, we found that Sestrin2 has a strong association with plasma atherogenicity and combats the progression of atherogenesis by regulating the AMPK-mTOR pathway. Metformin, an activator of...
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Dyslipidemia Fact Sheet in South Korea, 2022

Jin ES, Shim JS, Kim SE, Bae JH, Kang S, Won JC, Shin MJ, Jin HY, Moon J, Lee H, Kim HC, Jeong IK, on behalf of the Committee of Public Relation of the Korean Society of Lipid and Atherosclerosis

Objective: This study aimed to investigate the prevalence and status of dyslipidemia management among South Korean adults, as performed by the Korean Society of Lipid and Atherosclerosis under the name...
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Assessing the Practical Differences in LDL-C Estimates Calculated by Friedewald, Martin/Hopkins, or NIH Equation 2: An Observation CrossSectional Study

Wang I, Rahman MH, Hou S, Lin HW

Objective: Low-density lipoprotein-cholesterol (LDL-C) remains a clinically important cholesterol target in primary prevention of atherosclerotic cardiovascular disease. The present study aimed to assess the practical differences among three equations utilized...
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The Cardiovascular Effect of Tirzepatide: A Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Polypeptide Dual Agonist

Cho YK, Lee YL, Jung CH

Glucagon-like peptide-1 (GLP-1) receptor agonists have been used extensively in the clinic and have an established safety profile in cardiovascular disease settings. For the treatment of peptide-secreting enteroendocrine cells, most...
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Lipid-Lowering Efficacy of Combination Therapy With ModerateIntensity Statin and Ezetimibe Versus High-Intensity Statin Monotherapy: A Randomized, Open-Label, NonInferiority Trial From Korea

Choi H, Kang SH, Jeong SW, Yoon CH, Youn TJ, Song WH, Jeon DW, Lim SW, Lee JH, Cho SW, Chae IH, Kim CH

Objective: This phase IV, multicenter, randomized controlled, open-label, and parallel clinical trial aimed to compare the efficacy and safety of ezetimibe and moderate intensity rosuvastatin combination therapy to that of...
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Public Awareness of Dyslipidemia Among the Korean Population: A Survey Study

Bae JH, Jin ES, Kim SE, Kang S, Lee JY, Kim M, Jin HY, Shin MJ, Jeong IK, the Committee of Public Relation of the Korean Society of Lipid and Atherosclerosis

Objective: We aimed to assess the level of public awareness regarding dyslipidemia and its management among the Korean population. Methods: We conducted a web- or mobile-based survey study targeting the general...
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Elevated Lipoprotein(a) Levels and Atrial Fibrillation: A Systematic Review

Masson W, Barbagelata L, Nogueira JP, Corral P, Lavalle-Cobo A, Romeo FJ

Objective: The role of lipoprotein(a) (Lp[a]) as a possibly causal risk factor for atherosclerotic cardiovascular disease has been well established. However, the clinical evidence regarding the association between Lp(a) levels...
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