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A case report of primary T-cell lymphoma of the liver

Kim HS, Ko YH, Ree HJ

The patient was a 50-year-old woman who presented intermittent mild fever with elevated liver enzymes for 12 years. The liver biopsy showed diffuse portal and sinusoidal involvement of lymphoid cells...
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Defects in the differentiation and function of bone marrow-derived dendritic cells in non-obese diabetic mice

Lee M, Kim AY, Kang Y

Due to their high immunostimulatory ability as well as the critical role they play in the maintenance of self-tolerance, dendritic cells have been implicated in the pathogenesis of autoimmune diseases....
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Weber-Christian disease presenting with proptosis: a case report

Hyun SH, Kang YM, Kim CD, Lee JM, Kim IT, Kim NS

Weber-Christian disease (WCD) is a rare inflammatory disease of adipose tissue, which is characterized by painful cutaneous nodules and constitutional symptoms. Although any area of the body containing fat can...
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Changes in biochemical bone markers during pregnancy and puerperium

Yoon BK, Lee JW, Choi DS, Roh CR, Lee JH

To elucidate the changes in bone turnover during pregnancy and puerperium, we measured serially the levels of serum osteocalcin and urine deoxypyridinoline (Dpy) as markers of bone formation and bone...
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Clinical constellation of annular erythema associated with anti-Ro/La autoantibodies

Lee CW

Annular erythema (AE) associated with anti-Ro (SSA) and/or La (SSB) autoantibody in patients with Sjogren syndrome (SS) or with SS/systemic lupus erythematosus overlap syndrome (SS/SLE), has recently been described in...
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HFE gene mutation, C282Y causing hereditary hemochromatosis in Caucasian is extremely rare in Korean population

Lee JY, Yoo KH, Hahn SH

Hereditary hemochromatosis (HFE), which affects 1 in 400 and has an estimated carrier frequency of 1 in 10 individuals in Western population, results in multiple organ damage caused by iron...
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Myelomatous effusion with poor response to chemotherapy

Kim YM, Lee KK, Oh HS, Park SK, Won JH, Hong DS, Park HS, Park JS, Lee DW

While pleural effusion in multiple myeloma is relatively infrequent, myelomatous pleural effusion is extremely rare. We experienced a 61-year-old woman with IgD-lambda multiple myeloma and pleural effusion. The diagnosis was...
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Extranasal T/NK-cell lymphoma presenting as intestinal diverticulum

Lee YS, Kang CS, Kim BK, Shim SI

A case of intestinal angiocentric T/NK-cell lymphoma in a 58-year-old man is reported. The patient presented initially with panperitonitis because of perforation of sigmoid colon diverticulum. He underwent segmentectomy of...
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DNA ploidy patterns in gastric adenocarcinoma

Kim JY, Cho HJ

To assess the value of DNA ploidy, flow cytometric analysis was performed on unfixed fresh materials obtained from 86 patients with gastric cancer who underwent stomach resection. We evaluated the...
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Change of telomerase activity in rectal cancer with chemoradiation therapy

Kim HR, Kim YJ, Kim HJ, Kim SK, Lee JH

Telomerase, an enzyme associated with cellular immortality, is expressed by most malignant cells and is inactive in most normal somatic cells, with the exception of proliferative stem cells, germ cells...
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CT-guided celiac plexus block for intractable abdominal pain

Lee JM

Treatment of intractable abdominal pain due to inoperable intraabdominal malignancy is important, and the ineffectiveness of pharmacological agents has led many investigators to recommend chemical neurolysis of the celiac ganglions...
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Vesicular transport as a new paradigm in short-term regulation of transepithelial transport

Park CS, Leem CH, Jang YJ, Shim YH

The vectorial transepithelial transport of water and electrolytes in the renal epithelium is achieved by the polarized distribution of various transport proteins in the apical and basolateral membrane. The short-term...
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Comparison of respiratory indices in predicting response to high frequency oscillatory ventilation in very low birth weight infants with respiratory distress syndrome

Ko SY, Chang YS, Park WS

To evaluate the predictive values of oxygenation index (OI), arterial-alveolar oxygen tension ratio (a/APO)2, and alveolar-arterial oxygen gradient ((A-a)DO2) for early recognition of responsiveness to high frequency oscillatory ventilation (HFOV)...
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A case of myasthenia gravis proven by ultrastructural study

Hong SM, Khang SK, Kim KK, Bae Y, Park SH

Although light microscopic features of muscle are not pathognomonic in most cases of myasthenia gravis (MG), careful examination of neuromuscular junction by electron microscopy (EM) can reveal important clues for...
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Little role of anti-gB antibodies in neutralizing activity of patient's sera with human cytomegalovirus (HCMV) infection

Park JW, Kim DJ, Kim J, Park CG, Hwang ES, Cha CY

Human cytomegalovirus (HCMV) gB is known to play important roles in cell surface attachment, virion penetration, spread of infection from cell to cell, and provocation of neutralizing antibody. This study...
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Clinicopathologic analysis of 124 biopsy-proven peripheral nerve diseases

Hong SM, Ha H, Suh JH, Kim KK, Khang SK, Ro JY, Park SH

We reviewed dinical, histological and ultrastructural findings of 124 cases of sural nerve biopsy specimens to delineate the trends of peripheral nerve diseases in our institute. Eighty-one were men and...
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Pulmonary fibrosis in a steel mill worker

Leem JH, Hong YC, Song JS, Park W, Han HS

We report a case of pulmonary fibrosis in a 32-year-old man, who had worked at a steel mill and who died of respiratory failure due to interstitial fibrosis despite vigorous...
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Effects of decreased cerebral perfusion pressure on cerebral hemodynamics, brain cell membrane function and energy metabolism during the early phase of experimental Escherichia coli meningitis in the newborn piglet

Park WS, Chang YS

In this study, we tested the hypothesis that decreased cerebral perfusion pressure (CPP) induces cerebral ischemia and worsen brain damage in neonatal bacterial meningitis. Meningitis was induced by intracisternal injection...
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Plasminogen activator inhibitor-1 4G/5G promoter polymorphism and coagulation factor VII Arg353-->Gln polymorphism in Korean patients with coronary artery disease

Song J, Yoon YM, Jung HJ, Hong SH, Park H, Kim JQ

An increased risk for arterial thrombosis is associated with high plasma levels of coagulation and fibrinolytic factors such as PAI-1 and FVII. In this study, the 4G/5G polymorphism in the...
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Erythropoietin does not affect nitric oxide system in rats with chronic renal failure

Kim SW, Lee JU, Kang DG, Jung K, Kim NH, Suh SP, Choi KC, Kang YJ

We investigated to see whether an altered role of nitric oxide (NO) system is involved in erythropoietin (EPO)-induced hypertension in chronic renal failure (CRF). Male Sprague-Dawley rats were five-sixths nephrectomized...
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