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Baicalein Inhibits Dextran Sulfate Sodium-induced Mouse Colitis

Zhong X, Surh YJ, Do SG, Shin E, Shim KS, Lee CK, Na HK

  • J Cancer Prev.
  • 2019 Jun;24(2):129-138.
  • doi: 10.15430/JCP.2019.24.2.129
BACKGROUND: Baicalein is a bioactive flavone that is originally extracted from the root of Scutellaria baicalensis Georgi. This plant has long served as Chinese herbal medicine in the management of...
Esculetin Prevents the Induction of Matrix Metalloproteinase-1 by Hydrogen Peroxide in Skin Keratinocytes

Zhen AX, Piao MJ, Kang KA, Fernando P, Kang HK, Koh YS, Hyun JW

  • J Cancer Prev.
  • 2019 Jun;24(2):123-128.
  • doi: 10.15430/JCP.2019.24.2.123
BACKGROUND: Reactive oxygen species (ROS) are involved in various cellular diseases. Excessive ROS can cause intracellular oxidative stress, resulting in a calcium imbalance and even aging. In this study, we...
Ajoene, a Major Organosulfide Found in Crushed Garlic, Induces NAD(P)H:quinone Oxidoreductase Expression Through Nuclear Factor E2-related Factor-2 Activation in Human Breast Epithelial Cells

Cho SJ, Ryu JH, Surh YJ

  • J Cancer Prev.
  • 2019 Jun;24(2):112-122.
  • doi: 10.15430/JCP.2019.24.2.112
BACKGROUND: NAD(P)H:quinone oxidoreductase-1 (NQO1) is a widely-distributed flavin adenine dinucleotide-dependent flavoprotein that promotes obligatory 2-electron reductions of quinones, quinoneimines, nitroaromatics, and azo dyes. This reduces quinone levels and thereby minimizes...
Occupational Risk Factors for Prostate Cancer: A Meta-analysis

Krstev S, Knutsson A

  • J Cancer Prev.
  • 2019 Jun;24(2):91-111.
  • doi: 10.15430/JCP.2019.24.2.91
Prostate cancer is the second most common cancer in men worldwide. There are many occupational factors that have been suggested to cause prostate cancer. Our aim was to evaluate the...
The Roles of miRNAs in Medulloblastoma: A Systematic Review

Mollashahi B, Aghamaleki FS, Movafagh A

  • J Cancer Prev.
  • 2019 Jun;24(2):79-90.
  • doi: 10.15430/JCP.2019.24.2.79
Medulloblastoma is considered one of the most threatening malignant brain tumors with an extremely high mortality rate in children. In the medulloblastoma, there are several genes and mutations found to...
Therapeutic Effects of Amino Acids in Liver Diseases: Current Studies and Future Perspectives

Lee DY, Kim EH

  • J Cancer Prev.
  • 2019 Jun;24(2):72-78.
  • doi: 10.15430/JCP.2019.24.2.72
Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver and the third most common cause of cancer-related death worldwide. HCC is caused by infection of hepatitis...
The Role of Peroxiredoxin Family in Cancer Signaling

Kim Y, Jang HH

  • J Cancer Prev.
  • 2019 Jun;24(2):65-71.
  • doi: 10.15430/JCP.2019.24.2.65
Peroxiredoxins (Prxs) are antioxidant enzymes that protect cells from oxidative stress by reducing intracellular accumulation of reactive oxygen species (ROS). In mammalian cells, the six Prx isoforms are ubiquitously expressed...

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