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Black Bone Disease: Ochronotic Arthritis Detected during Knee Arthroplasty

Kang HW, Kim M, Oh JY, Youn C

Alkaptonuria is an extremely rare autosomal recessive metabolic disorder characterized by dark urine, ochronosis, and arthritis of the spine and major joints. We report a case of ochronotic arthritis observed...
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Position Statement: Atypical Femoral Fracture from the Korean Society for Bone and Mineral Research in 2023

Nho JH, Jang BW, Lee DW, Kim JH, Lim TK, Cha SM, Seo DK, Park YG, Kang DG, Lee YK, Ha YC

As the aging population increases, the number of patients with osteoporosis is gradually rising. Osteoporosis is a metabolic bone disease characterized by low bone mass and the microarchitectural deterioration of...
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The Effect of Denosumab in Elderly Patients Regarding Bone Density and Fracture Risk

Yoon SH, Kim K, Kim KC

Background: With an aging population, the importance of treating and diagnosing osteoporosis is increasing. Osteoporosis, previously known as a resorptive change primarily related to endocrinological mechanisms, is also being approached...
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Iris Koreana NAKAI Inhibits Osteoclast Formation via p38-Mediated Nuclear Factor of Activated T Cells 1 Signaling Pathway

Lee HY, Jung JE, Yim M

Background: Iris Koreana NAKAI (IKN) is a flowering perennial plant that belongs to the Iridaceae family. In this study, we aimed to demonstrate the effects of IKN on osteoclast differentiation...
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Dental Pulp Stem Cells and Current in vivo Approaches to Study Dental Pulp Stem Cells in Pulp Injury and Regeneration

Yang D, Solidum JGN, Park D

Dental pulp stem cells (DPSCs) have garnered significant interest in dental research for their unique characteristics and potential in tooth development and regeneration. While there were many studies to define...
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Advances in the Administration of Vitamin D Analogues to Support Bone Health and Treat Chronic Diseases

Kanemoto Y, Iwaki M, Sawada T, Nojiri K, Kurokawa T, Tsutsumi R, Nagasawa K, Kato S

Vitamin D (VD) exerts a wide variety of biological actions in addition to its well-known roles in calcium homeostasis. Nutritional VD deficiency induces rachitic abnormalities in growing children and osteomalacia...
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Osteoporosis Feature Selection and Risk Prediction Model by Machine Learning Using a Cross-Sectional Database

Cha Y, Seo SH, Kim JT, Kim JW, Lee SY, Yoo JI

Background: The purpose of this study was to verify the accuracy and validity of using machine learning (ML) to select risk factors, to discriminate differences in feature selection by ML...
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Effect of Artificial Intelligence or Machine Learning on Prediction of Hip Fracture Risk: Systematic Review

Cha Y, Kim JT, Kim JW, Seo SH, Lee SY, Yoo JI

Background: Dual energy X-ray absorptiometry (DXA) is a preferred modality for screening or diagnosis of osteoporosis and can predict the risk of hip fracture. However, the DXA test is difficult...
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