- Utility of Next-Generation Sequencing for Deciphering Intratumor Heterogeneity in Prostate Cancer
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Joung JG, Park JY, Yang SY, Jeong J
- KMID: 2516482
- Korean J Urol Oncol.
- 2021 May;19(2):101-108.
- doi: 10.22465/kjuo.2021.19.2.101
Prostate cancer has long been considered a disease with a heterogeneous phenotype. The intratumor heterogeneity (ITH) may affect diverse phenotypes such as treatment response, drug resistance, and overall clinical outcomes.... -
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- A Case of Caudal Regression Syndrome in the Newborn of the Diabetic Mother
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Park CH, Rho DY, Kim YW, Kim TU, Joung JG
- KMID: 2272290
- Korean J Obstet Gynecol.
- 2004 Feb;47(2):405-408.
The Caudal regression syndrome is characterized by sacrococcygeal or lumbosacrococcygeal agenesis, of variable extent, most often accompanied by multiple musculoskeletal abnormalities of the pelvis and legs. It is rare fetal... -
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- A Case of Pulmonary Embolism After Cesarean Delivery
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Kim GJ, Park CH, Rho DY, Kim YW, Park BJ, Shin HJ, Kim TU, Joung JG
- KMID: 2076859
- Korean J Obstet Gynecol.
- 2003 Mar;46(3):663-666.
During the past 50 years, the maternal mortality ratio has decreased dramatically. The leading causes of maternal deaths were pulmonary embolism, the complications of the pregnancy-induced hypertension, hemorrhage, the complications... -
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- Genome-Wide Association Study for the Identification of Novel Genetic Variants Associated with the Risk of Neuroblastoma in Korean Children
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Bae JS, Lee JW, Yoo JE, Joung JG, Yoo KH, Koo HH, Song YM, Sung KW
- KMID: 2507950
- Cancer Res Treat.
- 2020 Oct;52(4):1251-1261.
- doi: 10.4143/crt.2020.140
Purpose Neuroblastoma (NB) is the most common extracranial solid tumor found in children. To identify significant genetic factors for the risk of NB, several genetic studies was conducted mainly for Caucasians... -
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- Clinical Targeted Next-Generation sequencing Panels for Detection of Somatic Variants in Gliomas
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Shin H, Sa JK, Bae JS, Koo H, Jin S, Cho HJ, Choi SW, Kyoung JM, Kim JY, Seo YJ, Joung JG, Kim NKD, Son DS, Chung J, Lee T, Kong DS, Choi JW, Seol HJ, Lee JI, Suh YL, Park WY, Nam DH
- KMID: 2501200
- Cancer Res Treat.
- 2020 Jan;52(1):41-50.
- doi: 10.4143/crt.2019.036
Purpose Targeted next-generation sequencing (NGS) panels for solid tumors have been useful in clinical framework for accurate tumor diagnosis and identifying essential molecular aberrations. However, most cancer panels have been... -
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- Targeted exome sequencing resolves allelic and the genetic heterogeneity in the genetic diagnosis of nephronophthisis-related ciliopathy
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Kang HG, Lee HK, Ahn YH, Joung JG, Nam J, Kim NK, Ko JM, Cho MH, Shin JI, Kim J, Park HW, Park YS, Ha IS, Chung WY, Lee DY, Kim SY, Park WY, Cheong HI
- KMID: 2361538
- Exp Mol Med.
- 2016 Aug;48(8):e251.
- doi: 10.1038/emm.2016.63
Nephronophthisis-related ciliopathy (NPHP-RC) is a common genetic cause of end-stage renal failure during childhood and adolescence and exhibits an autosomal recessive pattern of inheritance. Genetic diagnosis is quite limited owing... -
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- Biomarker-guided targeted therapy in platinum-resistant ovarian cancer (AMBITION; KGOG 3045): a multicentre, open-label, five-arm, uncontrolled, umbrella trial
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Lee JY, Kim BG, Kim JW, Lee JB, Park E, Joung JG, Kim S, Choi CH, Kim HS, on behalf of Korean Gynecologic Oncology Group (KGOG) investigators
- KMID: 2537892
- J Gynecol Oncol.
- 2022 Jul;33(4):e45.
- doi: 10.3802/jgo.2022.33.e45
Objective Management of heavily pre-treated platinum-resistant ovarian cancer remains a therapeutic challenge. Outcomes are poor with non-platinum, single-agent chemotherapy (CT); however, molecularly targeted anticancer therapies provide new options. Methods This open-label, investigator-initiated, phase... -
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