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The Immunohistochemical Expression of E2F-1 Protein and DNA Topoisomerase II-alpha E2F-1 Protein in Colorectal Cancer and Their Relationship with Clinicopathologic Factors

Hwang SI, Lee TJ, Park YG, Ji GC, Lee JH, Chang IT, Park SI

  • KMID: 2004546
  • J Korean Surg Soc.
  • 2003 Jul;65(1):35-41.
PURPOSE: E2F-1 is a transcriptor that converts G1 to S in the cell cycle, and Topoisomerase II-alpha is a key enzyme in the metabolism of DNA, and an indicator of...
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Expression of p27Kip1 Protein and Correlation with Clinicopathologic Factors in Colorectal Carcinoma

Hong BK, Kim HJ, Lee TJ, Park YG, Ji GC, Chang IT, Park SI, Lee JH

  • KMID: 2145216
  • J Korean Surg Soc.
  • 2001 May;60(5):536-541.
PURPOSE: The p27Kip1 gene has been recognized as a negative regulator of the cell cycle and a potential tumor suppressor gene. Reduced expression of the p27Kip1 protein has been reported...
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