- Wnt Signal Transduction and Its Involvement in Human Diseases
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Jho EH
- KMID: 2100461
- J Korean Soc Endocrinol.
- 2005 Aug;20(4):306-318.
- doi: 10.3803/jkes.2005.20.4.306
No Abstract available. -
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- Pja2 Inhibits Wnt/β-catenin Signaling by Reducing the Level of TCF/LEF1
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Song Y, Lee S, Kim JR, Jho EH
- KMID: 2429557
- Int J Stem Cells.
- 2018 Nov;11(2):242-247.
- doi: 10.15283/ijsc18032
Ubiquitination of proteins plays an essential role in various cellular processes, including protein degradation, DNA repair, and cell signaling pathways. Previous studies have shown that protein ubiquitination is implicated in... -
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- Accumulation and Aberrant Modifications of alpha-Crystallins in Anterior Polar Cataracts
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Hwang KH, Lee EH, Jho EH, Kim JH, Lee DH, Chung SK, Kim EK, Joo CK
- KMID: 1734096
- Yonsei Med J.
- 2004 Feb;45(1):73-80.
- doi: 10.3349/ymj.2004.45.1.73
Crystallins are the major proteins found in the lens, and the localization of specific crystallins is well known. Overexpression and accumulation of alphaB-crystallin has been observed in response to stress... -
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- The Distinct Role of Tcfs and Lef1 in the Self-Renewal or Differentiation of Mouse Embryonic Stem Cells
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Kim S, Kim H, Tan A, Song Y, Lee H, Ying QL, Jho Eh
- KMID: 2504332
- Int J Stem Cells.
- 2020 Jul;13(2):192-201.
- doi: 10.15283/ijsc20044
Background and Objectives: Tcfs and Lef1 are DNA-binding transcriptional factors in the canonical Wnt signaling pathway. In the absence of β-catenin, Tcfs and Lef1 generally act as transcriptional repressors with... -
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- Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled
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Jung H, Kim HJ, Lee SK, Kim R, Kopachik W, Han JK, Jho EH
- KMID: 1009391
- Exp Mol Med.
- 2009 Oct;41(10):695-706.
- doi: 10.3858/emm.2009.41.10.076
Wnt signaling is known to be important for diverse embryonic and post-natal cellular events and be regulated by the proteins Dishevelled and Axin. Although Dishevelled is activated by Wnt and... -
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