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An Autopsy Confirmed Case of Amyotrophic Lateral Sclerosis with TDP Pathology

Je YR, Kim SY, Sung JJ, Lee MJ, Jung NY, Lee JH, Shin JH, Lee YM, Yoon JA, Park K, Ko J, Lee JM, Hwang C, Ahn JW, Sung S, Choi KU, Huh GY, Kim EJ

The phosphorylated 43-kDa transactive response DNA-binding protein (TDP-43) was identified as a major disease protein in sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration. We present a case with...
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Clinical Relevance of Enlarged Perivascular Spaces in Neurodegenerative Disease

Je YR, Ham HG, Park YH, Kim TY, Go Ms, Lee HI, Kim DE, Jung NY, Lee MJ, Seo SW, Kim EJ

Background: Enlarged perivascular space (ePVS) is recently reported to be associated with cerebral small vessel disease (SVD) and Alzheimer’s disease (AD). The topographical location of ePVS may relate to the...
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