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Anti-adipogenic Effect and Mechanism in 3T3-L1 Preadipocyte Differentiation by Salvianolic Acid B

Kwon HS, Jang BC

Salvianolic acid B (Sal B) is one of the most active hydrophilic compounds extracted from Salvia miltiorrhiza root. Previous in vitro and in vivo studies demonstrate the ability of Sal...
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2-Aryl Propionic Acid Amide Modification of Naproxen and Ibuprofen Dimers for Anti-neuroinflammatory Activity in BV2 mouse Microglial Cells

Ju H, Pachhapure S, Mufida A, Kim A, Elmaleh DR, Choi S, Jang BC

Inflammation is a common link in the pathophysiology of many neurological illnesses, including Alzheimer’s disease. Activated glial cells contribute to neuroinflammation by producing pro-inflammatory mediators. Naproxen and ibuprofen are nonsteroidal...
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The Growth Inhibitory Effect on B16F10 Melanoma Cells by 4-BPCA, an Amide Derivative of Caffeic Acid

Park Y, Kang SU, Lee J, Jang BC

Caffeic acid (CA) is a phenolic compound found naturally in plants and foods. CA and its natural derivatives are reported to have anti-cancer effects on many cancers, including melanoma. (E)-N-(4-Butylphenyl)-3-(3,4-dihydroxyphenyl)acrylamide...
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Interleukin 1β Up-Regulates mRNA Expression of Inducible Nitric Oxide Synthase in 3T3-L1 Preadipocytes: Role of JAKs/STATs, PKCs, and Src

Park YK, Wang S, Jang BC

Recent evidence suggests obesity as a low or systemic chronic inflammation. (Pre)adipocytes in the adipose tissue (AT) express and secrete a variety of cytokines and adipokines. Inducible nitric oxide synthase...
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Cucurbitacin E’s Anti-Cancer Effects on HCT116 Human Colon Cancer Cells by Controlling Expression and Phosphorylation Levels of Caspase-9, eIF-2α, and ATF-4

Yadav AK, Jang BC

Cucurbitacin E is a pivotal member of the cucurbitacin family and has been shown to have anti-cancer effects. However, until now, the anti-cancer effect and mode of action of cucurbitacin...
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Cryptotanshinone Inhibits Lipid Accumulation in Differentiating 3T3-L1 Preadipocytes by Down-regulating C/EBP-α, PPAR-γ, FAS, Perilipin A, and STAT-3

Park YK, Jang BC

Differentiation of preadipocyte, also named adipogenesis, leads to the phenotype of mature adipocyte that is filled with many lipid droplets. Excessive lipid accumulation in adipocytes leads to the development of...
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Cryptotanshinone Inhibits Lipid Accumulation in Differentiating 3T3-L1 Preadipocytes by Down-regulating C/EBP-α, PPAR-γ, FAS, Perilipin A, and STAT-3

Park YK, Jang BC

Differentiation of preadipocyte, also named adipogenesis, leads to the phenotype of mature adipocyte that is filled with many lipid droplets. Excessive lipid accumulation in adipocytes leads to the development of...
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Cryptotanshinone Inhibits Lipid Accumulation in Differentiating 3T3-L1 Preadipocytes by Down-regulating C/EBP-α, PPAR-γ, FAS, Perilipin A, and STAT-3

Park YK, Jang BC

Differentiation of preadipocyte, also named adipogenesis, leads to the phenotype of mature adipocyte that is filled with many lipid droplets. Excessive lipid accumulation in adipocytes leads to the development of...
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Prognostic Significance of Claudin 4 in Completely Resected Adenocarcinoma of the Lung

Chae MC, Park CK, Keum DY, Hwang I, Kwon KY, Jang BC

  • KMID: 2288790
  • Korean J Thorac Cardiovasc Surg.
  • 2014 Jun;47(3):262-268.
BACKGROUND: The development of diagnostic techniques and an awareness of health examinations can bring about an early diagnosis of lung cancer. However, appropriate postoperative management and adjuvant chemotherapy remain under...
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Down-regulation of IL-1beta-induced COX-2 Expression in A549 Lung Cancer Cells at Transcriptional Level by Leptomycin B Involves Inhibition of the IkappaB-alpha/NF-kappaB Pathway but Independent of CRM1

Park CK, Kim JB, Keum DY, Jang BC

PURPOSE: Overexpression of COX-2, an enzyme responsible fro the synthesis of prostaglandins, is well linked to human chronic lung diseases. The mechanism by which COX-2 expression is increased or enhanced...
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Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets

Cho JW, Park K, Kweon GR, Jang BC, Baek WK, Suh MH, Kim CW, Lee KS, Suh SI

  • KMID: 1056230
  • Exp Mol Med.
  • 2005 Jun;37(3):186-192.
Ultraviolet B (UVB) irradiation of skin induces an acute inflammation. Cyclooxygenase-2 (COX-2) protein plays key roles in acute inflammation in UVB-irradiated keratinocyte cell line HaCaT. Recently, curcumin has been regarded...
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Expression of Human beta-defensin 2 mRNA by Lipopolysaccharide in Human Corneal Epithelial Cells

Bae EH, Park KW, Kim JW, Jang BC, Lim KJ, Jung TY, Kwon YK, Shin SW, Kim SP, Park JH, Kwon TK, Baek WK, Suh MH, Suh SI

  • KMID: 2054984
  • J Bacteriol Virol.
  • 2004 Mar;34(1):27-38.
Recently the transcriptional up-regulation of human beta-defensin 2 (HBD-2) by lipopolysaccharide (LPS) was found to be associated with NF-kappaB binding site. Although the general mechanisms of NF-kappaB activation by LPS...
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Identification of Molecular Defects in Korean Patients with Marfan Syndrome

Shin MS, Park HY, Lim Y, Shin GJ, Jang Y, Jang BC, Chung N

BACKGROUND AND OBJECTIVES: Marfan syndrome is an autosomal dominant heritable disease of connective tissue which is characterized by cardinal features mainly in the cardiovascular, ocular and skeletal systems. Aneurysms or...
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Prosthetic Mitral Valve Thrombosis

Ha JW, Jung NS, Jang BC

  • KMID: 2204372
  • J Korean Soc Echocardiogr.
  • 2000 Jun;8(1):5-6.
No abstract available.
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Arterry Bypas Graft with the Right Gastroepiploic Artery: Clinical and Angiographic Short-Term Results

Lee HS, Jang BC, Lee SS, Kim JY, Maeng DH, Park HD, Yoon YN, Jang JS

  • KMID: 2433865
  • Korean J Thorac Cardiovasc Surg.
  • 2000 Feb;33(2):151-159.
BACKGROUND: The right gastroepiploic artery(RGEA) has been use in coronary artery bypass grafting from 1987. The RGEA is the most useful arterial conduit in coronary artery bypass grafting(CABG) followed by the internal...
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Coexpression of cyclooxygenase-2 and matrix metalloproteinases in human aortic atherosclerotic lesions

Hong BK, Kwon HM, Lee BK, Kim D, Kim IJ, Kang SM, Jang Y, Cho SH, Kim HK, Jang BC, Cho SY, Kim HS, Kim MS, Kwon HC, Lee N

Inflammation appears to have a major role in the development of atherosclerosis. Cyclooxygenase-2 (COX-2) is involved in the inflammatory response via the generation of prostanoids that, in turn, are involved...
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Pregnancy in Patients with Prosthetic Heart Valve

Lee SY, Jang BC, Park HG, Park YW, Kang MS, Hong SN, Cho BK, Hong PH

  • KMID: 2288921
  • Korean J Thorac Cardiovasc Surg.
  • 1999 Nov;32(11):1023-1030.
BACKGROUND: This is a retrospective study of 42 pregnancies from 33 women with prosthetic heart valves who were on anticoagulation regimen prior to or during their pregnancy. MATERIAL AND METHOD:...
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Endovascular Treatment of Abdominal Aortic Aneurysm by Bifurcated Stent Graft

Ko HK, Lee DY, Shim WH, Jang BC, Yoon CS, Won JH, Won JY, Kang BC

PURPOSE: To evaluate the effectiveness and safety of endoluminal bifurcated stent graft for the treatment of AAA. MATERIALS AND METHODS: Between August 1997 and August 1998, 20 patients with AAA...
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Bifurcated Stent-Graft(Vanguard) for the Endovascular Treatment of Abdominal Aortic Aneurysm

Shim WH, Choi D, Yoon YS, Lee DY, Jang BC

PURPOSE: The purpose of this study was to evaluate the safety, feasibility and effectiveness of an endoluminally-placed bifurcated stent-graft (Vanguard) for the treatment of infrarenal abdominal aortic aneurysm (AAA). METHODS:...
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Fat Embolism Syndrome

Jang BC

  • KMID: 1529919
  • J Korean Soc Aesthetic Plast Surg.
  • 1999 Mar;5(1):41-46.
No abstract available.
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