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Effects of Prior Short-term Ischemic Preconditioning on Sitting-Induced Lower Limb Vascular Dysfunction in Healthy Men

Won JH, Jae SY

Purpose: The purpose of the study was to examine whether a 7-day ischemic preconditioning (IPC) intervention would attenuate the prolonged sitting-induced lower limb vascular dysfunction in healthy men. Methods: In a...
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Role of Ischemic Preconditioning in the Cardioprotective Mechanisms of Monomeric C-Reactive Protein-Deposited Myocardium in a Rat Model

Kim EN, Choi JS, Kim CJ, Kim SR, Oh SJ

Background: The deposition of monomeric C-reactive protein (mCRP) in the myocardium aggravates ischemia-reperfusion injury (IRI) and myocardial infarction. Ischemic preconditioning (IPC) is known to protect the myocardium against IRI. Methods: We...
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Effects of Remote Ischemic Pre-Conditioning to Prevent Contrast-Induced Nephropathy after Intravenous Contrast Medium Injection: A Randomized Controlled Trial

Belabbas D, Koch C, Chaudru S, Lederlin M, Laviolle B, Pabic EL, Boulmier D, Heautot JF, Mahe G

Objective: We aimed to assess the effects of remote ischemic pre-conditioning (RIPC) on the incidence of contrast-induced nephropathy (CIN) after an intravenous (IV) or intra-arterial injection of contrast medium (CM)...
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Impact of Previous Angina on Clinical Outcomes in ST-Elevation Myocardial Infarction Underwent Percutaneous Coronary Intervention

Han X, Jeong MH, Won J, Kim Y, Kim MC, Sim DS, Hong YJ, Kim JH, Ahn Y

The present study sought to assess the impact of previous angina symptoms on real world clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) who had undergone successful percutaneous coronary...
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Effect of Remote Ischemic Preconditioning on Maximal Exercise Tolerance in Young Adults

Yoon ES, Jae SY

PURPOSE: Remote ischemic preconditioning (RIPC), induced by repeated bouts of ischemia followed by reperfusion of the arm or leg is a noninvasive strategy to protect a target organ against oxidative...
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The optimal duration of ischemic preconditioning for renal ischemia-reperfusion injury in mice

Choi HS, Hwang JK, Kim JG, Hwang HS, Lee SJ, Chang YK, Kim JI, Moon IS

PURPOSE: The aim of the present study was to investigate the protective effects of ischemic preconditioning for different periods of time and to elucidate the optimal safe ischemic preconditioning time...
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Effects of Remote Ischemic Conditioning Methods on Ischemia-Reperfusion Injury in Muscle Flaps: An Experimental Study in Rats

Keskin D, Unlu RE, Orhan E, Erkilinç , Bogdaycioglu N, Yilmaz FM

BACKGROUND: The aim of this study was to investigate the effects of remote ischemic conditioning on ischemia-reperfusion injury in rat muscle flaps histopathologically and biochemically. METHODS: Thirty albino rats were divided...
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Remote Ischemic Preconditioning Enhances the Expression of Genes Encoding Antioxidant Enzymes and Endoplasmic Reticulum Stress-Related Proteins in Rat Skeletal Muscle

Park UJ, Kim HT, Cho WH, Park JH, Jung HR, Kim MY

PURPOSE: Ischemic preconditioning (IPC), including remote IPC (rIPC) and direct IPC (dIPC), is a promising method to decrease ischemia-reperfusion (IR) injury. This study tested the effect of both rIPC and...
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The Effect of Ischemic Preconditioning on the Expression of Serum Cytokines after 2 Hours Ischemia and Timely Reperfusion in the Hindlimb of Mice

Jin JH, Kim SJ, Seo Y, Kim S

The large volume of reactive oxygen species are generated during reperfusion after transient or post-procedural ischemia, which leads to cell injury. This ischemia-reperfusion (IR) injury may cause local and even...
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The Effects of Acute Resistance Exercise on Ischemia-Reperfusion Injury-Induced Macro and Microvascular Dysfunction in Healthy Young Adults

Yoon ES, Park SH, Lee YH, Lee C, Jae SY

Ischemia reperfusion injury (IRI) leads to a temporary decrease in macrovascular function, but whether IRI causes microvascular dysfunction is not known. Resistance exercise involves muscular contractions that can make downstream...
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Effects of Ischemic Preconditioning of Different Intraoperative Ischemic Times of Vascularized Bone Graft Rabbit Models

Halim AS, Wan Ahmad Kamal WSR, Noor NM, Abdullah S

BACKGROUND: Ischemic preconditioning has been shown to improve the outcomes of hypoxic tolerance of the heart, brain, lung, liver, jejunum, skin, and muscle tissues. However, to date, no report of...
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Changes in HO-1, HSP70 and iNOS Expressions in the Rat Liver after Remote Ischemic Preconditioning

Jeon SK, Seo YK, Paik DJ

Ischemic preconditioning (IP), short pre-treatment sublethal ischemia, induces a state of protection against subsequent prolonged ischemia-reperfusion. The purpose of this study was to investigate the expression of HO-1, HSP70, and...
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Immediately transcripted genes in various hepatic ischemia models

Choi KK, Cho JA, Kim SH, Lee SW, Min SO, Kim KS

PURPOSE: To elucidate the characteristic gene transcription profiles among various hepatic ischemia conditions, immediately transcribed genes and the degree of ischemic injury were compared among total ischemia (TI), intermittent clamping...
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Hepatic Ischemic Preconditioning Provides Protection Against Distant Renal Ischemia and Reperfusion Injury in Mice

Lee JA, Choi JW, In JH, Jung HS, Kim YS, Jeon YS, Kang YJ, Kim DW, Lim YG, Park JH, Joo JD

We previously demonstrated that there are acute and delayed phases of renal protection against renal ischemia and reperfusion (IR) injury with renal ischemic preconditioning (IPC). This study assessed whether hepatic...
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Morphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes

Kim JM, Jang YH, Kim J

During the past few decades, a large number of animal studies demonstrated that commonly used opioids could provide cardioprotection against ischemia-reperfusion (I/R) injury. Opioid-induced preconditioning or postconditioning mimics ischemic preconditioning...
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Ischemic postconditioning protects cardiomyocytes against ischemia/reperfusion injury by inducing MIP2

Zhu HL, Wei X, Qu SL, Zhang C, Zuo XX, Feng YS, Luo Q, Chen GW, Liu MD, Jiang L, Xiao XZ, Wang KK

Cardiomyocytes can resist ischemia/reperfusion (I/R) injury through ischemic postconditioning (IPoC) which is repetitive ischemia induced during the onset of reperfusion. Myocardial ischemic preconditioning up-regulated protein 2 (MIP2) is a member...
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The effect of preconditioning on liver regeneration after hepatic resection in cirrhotic rats

Min SO, Kim SH, Lee SW, Cho JA, Kim KS

BACKGROUND/AIMS: Ischemic preconditioning (IP) decreases severity of liver necrosis and has anti-apoptotic effects in previous studies using liver regeneration in normal rats. This study assessed the effect of IP on...
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Neuroprotective Effect of Ischemic Preconditioning in Traumatic Brain Injured Rats

Yang HS, Chun MH, Park JY, Kim BR, Kim ST, Cho HJ

  • KMID: 2326496
  • J Korean Acad Rehabil Med.
  • 2010 Dec;34(6):656-662.
OBJECTIVE: To test the hypothesis that a transient non-lethal ischemia (ie. ischemic preconditioning(IPC)) would protect against subsequent traumatic brain injury (TBI) using 1H-magnetic resonance spectroscopy (MRS). METHOD: Sprague-Dawley rats were randomized...
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The effect of mitochondrial adenosine triphosphate-sensitive potassium (K(ATP)) channel blocker on ischemic preconditioning in hypoxic-ischemic brain injury model of neonatal rat

Park YS, Bang JY, Hwang BY, Ryu HY, Jeong SM, Park PH

BACKGROUND: A brief episode of cerebral ischemia confers transient ischemic tolerance to a subsequent ischemic challenge that is otherwise lethal to them. This study was purposed to evaluate the effect...
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Effects of Ischemic Preconditioning on the Phosphorylation of Akt and the Expression of SOD-1 in the Ischemic-reperfused Rat Skeletal Muscles

Seo YK, Paik DJ

  • KMID: 1469870
  • Korean J Phys Anthropol.
  • 2009 Jun;22(2):153-162.
Akt, a key protein of cell survival, can promote cell growth and survival by activations of various cellular protective factors. Ischemic preconditioning (IP) has been known to reduce ischemic injury...
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