Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

PUBLICATION DATE

28 results
Display

Effects of carnosine and hypothermia combination therapy on hypoxic-ischemic brain injury in neonatal rats

Byun JC, Lee SR, Kim CS

Background: Carnosine has antioxidative and neuroprotective properties against hypoxic-ischemic (HI) brain injury. Hypothermia is used as a therapeutic tool for HI encephalopathy in newborn infants with perinatal asphyxia. However, the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Upregulation of miR-20b Protects Against Cerebral Ischemic Stroke by Targeting Thioredoxin Interacting Protein (TXNIP)

Yang D, Tan Y, Li H, Zhang X, Li X, Zhou F

  • KMID: 2515815
  • Exp Neurobiol.
  • 2021 Apr;30(2):170-182.
  • doi: 10.5607/en20046
Dysregulation of microRNAs (miRNAs) is involved in abnormal development and pathophysiology in the brain. Although miR-20b plays essential roles in various human diseases, its function in cerebral ischemic stroke remains...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Changes in plasma lipoxin A4, resolvins and CD59 levels after ischemic and traumatic brain injuries in rats

Jung JS, Kho AR, Lee SH, Choi BY, Kang SH, Koh JY, Suh SW, Song DK

Ischemic and traumatic brain injuries are the major acute central nervous system disorders that need to be adequately diagnosed and treated. To find biomarkers for these acute brain injuries, plasma...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of Dizocilpine (MK-801) via Up-modulation of N-methyl-D-aspartate (NMDA) Receptors on Hypoxic-Ischemic Brain Injury in Neonatal Rats

Kim JH, Lee HJ, Lee EJ, Choi EJ, Kim JK, Chung HL, Kim WT

OBJECTIVE: Several studies have demonstrated the neuroprotective effects of (+)-MK-801 hydrogen maleate (dizocilpine), in various animal models of hypoxic-ischemic (HI) brain injury. However limited data are available on the neonatal...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Therapeutic Application of Neural Stem Cells for Neonatal Hypoxic-ischemic Brain Injury

Park KI, Goo K, Jung K, Kim M, Kim IS, Yun S, Lee IS, Shin JE, Yu HY, Eun HS, Kim JE, Namgung R, Lee C

  • KMID: 2312947
  • Neonatal Med.
  • 2013 Aug;20(3):343-353.
Neural stem cells (NSCs) are characterized by a capacity for self-renewal, differentiation into multiple neural cell lineages, and migration toward damaged sites in the central nervous system (CNS). NSCs expanded...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neuroprotective Effects of a Butanol Fraction of Rosa hybrida Petals in a Middle Cerebral Artery Occlusion Model

Yang G, Park D, Lee SH, Bae DK, Yang YH, Kyung J, Kim D, Choi EK, Hong JT, Jeong HS, Kim HJ, Jang SK, Joo SS, Kim YB

  • KMID: 2170663
  • Biomol Ther.
  • 2013 Nov;21(6):454-461.
The neuroprotective effects of a butanol fraction of white rose petal extract (WRPE-BF) were investigated in a middle cerebral artery occlusion (MCAO) model. Seven week-old male rats were orally administered...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neuroprotective Effects of Dizocilpine (MK-801) Via Mediation of Nitric Oxide Synthase on Hypoxic-ischemic Brain Injury in Neonatal Rats

Jo JY, Lee HJ, Choi EJ, Kim JK, Chung HL, Kim WT

  • KMID: 2280826
  • Korean J Perinatol.
  • 2011 Sep;22(3):181-193.
PURPOSE: Current studies have demonstrated the neuroprotective effects of dizocilpine (MK-801) in many animal models of brain injury, including hypoxic-ischemic (HI) encephalopathy, trauma and excitotoxicity, but limited data are available...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Clinical applications of human neural stem cells in neurodegenerative diseases, especially neonatal hypoxic-ischemic brain injury and spinal cord injury

Park KI

Multipotent neural stem cells (NSCs) are operationally defined by their ability to self-renew, to differentiate into cells of all glial and neuronal lineages throughout the neuraxis, and to populate developing...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neuroprotective Effect of Dizocilpine (MK-801) via Anti-apoptosis on Hypoxic-ischemic Brain Injury in Neonatal Rats

Seo MA, Lee HJ, Choi EJ, Kim JK, Chung HL, Kim WT

  • KMID: 2321487
  • J Korean Soc Neonatol.
  • 2010 Nov;17(2):181-192.
PURPOSE: Current studies have demonstrated the neuroprotective effects of dizocilpine (MK-801) in many animal models of brain injury, including hypoxic-ischemic (HI) encephlopathy, trauma and excitotoxicity, but limited data are available...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The neuroprotective effect of recombinant human erythropoietin via an antiapoptotic mechanism on hypoxic-ischemic brain injury in neonatal rats

Kim MS, Seo YK, Park HJ, Lee KH, Lee KH, Choi EJ, Kim JK, Chung HL, Kim WT

PURPOSE: The neuroprotective effects of erythropoietin (EPO) have been recently shown in many animal models of brain injury, including hypoxic-ischemic (HI) encephalopathy, trauma, and excitotoxicity; however, limited data are available...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Taurine exerts neuroprotective effects via anti-apoptosis in hypoxic-ischemic brain injury in neonatal rats

Jeong JE, Kim TY, Park HJ, Lee KH, Lee KH, Choi EJ, Kim JK, Chung HL, Seo ES, Kim WT

PURPOSE: Taurine (2-aminoethanesulfonic acid) is a simple sulfur-containing amino acid. It is abundantly present in tissues such as brain, retina, heart, and skeletal muscles. Current studies have demonstrated the neuroprotective...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neuroprotection of Recombinant Human Erythropoietin Via Modulation of N-methyl-D-aspartate Receptors in Neonatal Rats with Hypoxic-ischemic Brain Injury

Jang YJ, Seo ES, Kim WT

  • KMID: 2144496
  • J Korean Soc Neonatol.
  • 2009 Nov;16(2):221-233.
PURPOSE: Erythropoietin (EPO) has neuroprotective effects in many animal models of brain injury, including hypoxic-ischemic (HI) encephalopathy, trauma, and excitotoxicity. Current studies have demonstrated the neuroprotective effects of EPO, but...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The expression patterns of nitric oxide synthases (NOS) by resveratrol in hypoxic-ischemic brain injury in neonatal rat model

Seo MA, Jang YY, Choi EJ, Kim JK, Lee SJ, Seo ES, Chung HL, Kim WT

  • KMID: 2280779
  • Korean J Perinatol.
  • 2008 Sep;19(3):283-292.
OBJECTIVE: Resveratrol, a polyphenolic phytoalexin, is extracted abundantly from the red wine and grapes and biosynthesized as a defense agent to infection, ultraviolet and ozon etc. Recently, The cancer-preventive, anti-inflammatory...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neuroprotective effects of geneticin (G418) via apoptosis in perinatal hypoxic-ischemic brain injury

Ju M, Lee HJ, Lee SJ, Seo ES, Park HJ, Lee KY, Lee GH, Choi EJ, Kim JK, Lee JW, Chung HL, Kim WT

PURPOSE: Some antibiotics were known to exert neuroprotective effects in the animal model of hypoxic-ischemic (H-I) brain injury, but the mechanism is still unclear. A recent study reported that geneticin...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Neuroprotective effects of resveratrol via anti-apoptosis on hypoxic-ischemic brain injury in neonatal rats

Shin JY, Seo MA, Choi EJ, Kim JK, Seo ES, Lee JH, Chung HL, Kim WT

PURPOSE: Resveratrol, extracted from red wine and grapes, has an anti-cancer effect, an antiinflammatory effect, and an antioxidative effect mainly in heart disease and also has neuroprotective effects in the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Functional Improvement by Human Adipose Tissue Stromal Cells after Cerebral Ischemia in Rats

Lee TH

  • KMID: 2224460
  • Korean J Anat.
  • 2007 Sep;40(3):211-218.
Adipose tissue may represent an alternative source of cells capable of neuronal differentiation, potentially enhancing their usefulness in the treatment of neurological disease. We examined that human adipose tissue stromal...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Expression of Fibroblast Growth Factor Receptor mRNAs according to Administration of Geneticin in Hypoxic Neuron Cell Culture

Keum KH, Seo ES, Kim WT

  • KMID: 1750713
  • J Korean Soc Neonatol.
  • 2007 Nov;14(2):162-169.
PURPOSE: Recently, Geneticin (G418) were known to exert neuroprotective effects in the hypoxic-ischemic (H-I) brain injury, but the mechanism is still unclear. The roles of fibroblast growth factor (FGF) and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effect of the Heme Oxygenase Inhibitor on the Hypoxic Ischemic Brain Injury in the Neonatal Rat

Bang JY, Park PH

BACKGROUND: The heme oxygenase system catalyzes the conversion of heme to free iron, carbon monoxide and bilirubin. This study was purposed to evaluate the effect of the heme oxygenase inhibitor,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The Protective Effect of Ischemic and Hypoxic Preconditioning on Hypoxic-ischemic Brain Injury in the Neonatal Rat: 1H Magnetic Resonance Spectroscopic Study

Jeong SM, Jung HS, Choi JM, Bang JY, Lim KH, Park PH

BACKGROUND: A brief episode of cerebral ischemia confers transient ischemic tolerance to a subsequent ischemic challenge. We examined the effect of ischemic and hypoxic preconditioning in the neonatal rat. METHODS:...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Alterations of Insulin-like Growth Factor-I mRNA and IGF Binding Protein-5 mRNA Expression Following Hypoxic-Ischemic Brain Injury in Immature Rat

Lee KH, Lim JH, Choi BM, Eun BL

  • KMID: 2193580
  • J Korean Soc Pediatr Endocrinol.
  • 2003 Jun;8(1):56-63.
PURPOSE:Insulin-like growth factor-I(IGF-I) is an essential anabolic factor for postnatal rat brain development and IGF-I expression is highly abundant during the first 21 days, critical growth period. Hypoxic-ischemic brain insults...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2021 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr