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Comparative Analysis of the Expression of Involucrin, Filaggrin and Cytokeratin 4, 10, 16 in Cholesteatoma

Min HJ, Park CW, Jeong JH, Cho SH, Kim KR, Lee SH

BACKGROUND AND OBJECTIVES: The aim of this study is to determine whether the hyperproliferative and hyperkeratotic characters of cholesteatoma are associated with differentiation of keratinocytes in cholesteatoma by examining the...
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The Expression of Human Beta Defensins by Thermal Injury

Jeong HS, Yeon CJ, Lee JS

  • KMID: 1439461
  • J Korean Burn Soc.
  • 2012 Jun;15(1):39-44.
PURPOSE: Defensins are important components of innate immune system. These peptides have antimicrobial activity against a wise variety of pathogens that associated with burn wound infection. In particular, human beta-defensins...
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Histologic morphology and involucrin, filaggrin, and keratin expression in normal canine skin from dogs of different breeds and coat types

Theerawatanasirikul S, Suriyaphol G, Thanawongnuwech R, Sailasuta

The purpose of this study was to measure the thickness of canine epidermis at various anatomical sites according to localization of cornified envelopes (involucrin and filaggrin), keratins (keratin 10, 5),...
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The Expressions of Cytokeratin 16, Involucrin and PCNA in Clear Cell Acanthoma on Areola

Kim SY, Choi HY, Myung KB, Choi YW

  • KMID: 2302164
  • Korean J Dermatol.
  • 2007 Aug;45(8):804-810.
BACKGROUND: Clear cell acanthoma usually appears as an asymptomatic nodule on the leg. It has an unusual clinical feature in that it is presented as chronic eczema on the areola....
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The Effects of Testosterone on Skin Barrier

Bak H, Choi EH, Lee KG, Hong SP, Lee SH, Ahn SK

  • KMID: 1590919
  • Korean J Dermatol.
  • 2005 Feb;43(2):167-176.
BACKGROUND: Although there are no known gender-related differences in permeability barrier function in adults, estrogen accelerates whereas testosterone retards barrier development in fetal skin. However, there have been few studies...
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Distribution Patterns of Involucrin in the Stratum Corneum of the Normal and Psoriatic Artificial Skins

Song IH, Sung HK, Kim JY, Sung EK, Lee Y, Park JH, Moon YS, Kim HT, Chang SI

  • KMID: 2030762
  • Korean J Anat.
  • 2004 Apr;37(2):191-198.
Cornified envelope is highly insoluble structure formed beneath the plasma membrane during terminal differentiation of keratinocytes and is stabilized by cross linking of various proteins, including involucrin, loricrin, and cornifin....
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bcl-2 and Involucrin Expression in Basal Cell Carcinoma and Squamous Cell Carcinoma

Kim YC, Park HJ, Cinn YW

  • KMID: 2086744
  • Korean J Dermatol.
  • 2003 Nov;41(11):1494-1499.
BACKGROUND: The histologic distinction between basal cell carcinoma(BCC) and squamous cell carcinoma(SCC) is sometimes difficult, but clinically important because the risk of progressive disease is significantly higher with SCC than...
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Immunohistochemical Study of Expression of Involucrin, Loricrin, Filaggrin and Bcl-2 in Psoriasis

Kim KD, Kim HJ, Kim NI

  • KMID: 2013633
  • Korean J Dermatol.
  • 2002 May;40(5):506-512.
BACKGROUND: The pathogenesis of psoriasis remains uncertain. It is known that a variety of factors take a role in its pathogenesis. One of them is the alteration of keratinocytes differentiation....
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Change of Stratification of Three Dimensional Culture by Gingival Keratinocytes & Fibroblasts

Jung TH, Hyun HN, Kim YS, Kim EC, You HK, Shin HS

Epithelial-mesenchymal interaction plays a important role in cell growth and differentiation. This interaction is already well known to have an importance during the organ development as well as cell growth...
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Replicative Senescence and Differentiation Properties of Reconstituted Skin and Monolayer Human Keratinocytes in Vitro

Doh YH, Liu Y, Sung HK, Jung TE, Park JH, Kim JY, Song IH, Lee YC, Sung EG

  • KMID: 1558765
  • Korean J Anat.
  • 2001 Dec;34(6):553-565.
This experiment tried to elucidate the characteristics of senescence and differentiation in the reconstituted skin and the monolayer cultured human keratinocytes in vitro, respectively. While the keratinocytes were cultivated from...
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The Measurement of Double Staining for Senescence Associated-beta-Galactosidase Activity and Keratin 10 or Involucrin in Monolayer and Organotypic Cultured Keratinocytes

Kim JW, Liu Y, Sung HK, Jung TE, Park JH, Kim JY, Song IH, Lee YC, Sung EG

  • KMID: 1558764
  • Korean J Anat.
  • 2001 Dec;34(6):545-552.
This experiment developed the methodology of double staining for senescence associated-beta-galactosidase (SA-beta-gal) activity and keratin 10 (K10) or involucrin. To prove the usefulness of the double staining, the author investigated...
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Clinicohistopathologic Findings in Keratoacanthoma and its Immunohi-stochemical Study of Ki-67, p53, bcl-2 and Involucrin Protein Expression

Kwon SD, Kye YC, Kim SN

  • KMID: 2146468
  • Korean J Dermatol.
  • 2000 Dec;38(12):1630-1640.
BACKGROUND: Keratoacanthoma(KA) is common, benign cutaneous tumor that is most likely derived from hair follicle cells, and most often occurs on sun-exposed sites in light-skinned persons of middle age or...
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Expression of Involucrin and Filaggrin in Various Skin Disorders: Immunohistochemical Study

Lee SC, Lee JB, Seo JJ, Park JY, Won YH

  • KMID: 2303366
  • Korean J Dermatol.
  • 1999 Jun;37(6):708-714.
BACKGROUND: The cornified cell envelope (CE) is a unique structure found in the terminal differentiation of the skin. The precursor proteins of the CE are composed of many candidate structural...
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Expression Patterns of Cytokeratin and Involucrin in the Epidermis of the Artificial Skin Reconstructed by Cultured Cells

Song IH, Lee CK, Sung EK

  • KMID: 2071845
  • Korean J Phys Anthropol.
  • 1999 Jun;12(1):83-90.
To investigate differentiation and growth process of keratinocytes in organotypic cultured skin, we carried out immunohistochemical studies for cytokeratin (CK) 10, 14, 16, 17 and involucrin in the cultured skin....
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Immunohistochemical Study for Differentiation of Human Middle Ear Cholesteatoma

Park KH, Park HJ, Chun YM, Lee JS, Kim HJ

  • KMID: 2274517
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Dec;41(12):1521-1526.
BACKGROUND AND OBJECTIVES: Human epidermis is a continuously dividing tissue, in which keratinocytes gradually differentiate and mature while moving from basal cells to suprabasal cell layers. Epidermal homeostasis is maintained...
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Development of Psoriasis Model in Vitro

Song IH, Sung EK, Kim JY, Lee YC, Lee MS

  • KMID: 1530295
  • Korean J Anat.
  • 1998 Dec;31(6):923-935.
Psoriasis is a disease caused by hyperproliferation of keratinocytes. Pathogenesis of psoriasis is still unclear, but many reports suggest that psoriatic keratinocytes themselves may have some factors of pathogenesis. The...
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Expression of cytokeratins and involucrin in cultured human keratinocytes

Song IH, Doh YH, Kim JY, Lee YC, Sung EG

  • KMID: 1937878
  • Korean J Anat.
  • 1998 Oct;31(5):663-671.
To evaluate the maturation and differentiation state of cultured keratinocytes, the author investigated expression of differentiation markers in cultured keratinocytes. The specimens were divided into three experimental groups, 3rd passage...
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A study on cytokeratin and involucrin expression in the epidermis of nevus sebaceus

Cho KH, Kim YG, Cho MK, Chi JG

  • KMID: 2230922
  • Korean J Dermatol.
  • 1992 Jun;30(3):279-290.
Thirty two cases of nevus sebaceus were studied by immunohistochemical staining employing three anticytokeratin antibodies(34bE, 34bB, CAM 5.2) and anti-involucrin antibody in order to clarify the biochemical characteristics of the...
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Involucrin Expression in Epidermal Tumors

Moon DC, Hyun MK, Kwon KS, Chung TA

  • KMID: 1930835
  • Korean J Dermatol.
  • 1989 Apr;27(2):145-156.
Involucrin is a recently recognized structural component of mature squamous epithelial cells and is considered as a marker of normal eratinocyte differentiation and ma.turation. In this study peroxidase-antiperoxidase techniques were...
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