- Single-Level Cervical Artificial Disc Replacement Compared with Cage Screw Implants: 2-Year Clinical and Radiological Outcomes Especially Adjacent Level Ossification
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Evan TYZ, Yen JWR, Seow D, Jiali CC, Kumar L, Baskar S, Liang S, Kumar N
- KMID: 2545391
- Asian Spine J.
- 2023 Aug;17(4):729-738.
- doi: 10.31616/asj.2022.0302
Study Design: Retrospective single-center, single-surgeon cohort study. Purpose: Our goal was to compare the 2-year clinical and radiological results of artificial disc replacement (ADR) and cage screw (CS) implants in patients... -
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- Extra Cellular Matrix Remodeling: An Adjunctive Target for Spinal Cord Injury and Intervertebral Disc Degeneration
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Kumar A, Kumar N, Pathak Z, Kumar H
- KMID: 2533791
- Neurospine.
- 2022 Sep;19(3):632-645.
- doi: 10.14245/ns.2244366.183
The extracellular matrix (ECM) is a protein-and-carbohydrate meshwork that supports a variety of biological structures and processes, from tissue development and elasticity to the preservation of organ structures. ECM composition... -
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- Early Postoperative Loss of Disc Height Following Transforaminal and Lateral Lumbar Interbody Fusion: A Radiographic Analysis
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Kaliya-Perumal AK, Soh TLT, Tan M, Oh JYL
- KMID: 2532965
- Asian Spine J.
- 2022 Aug;16(4):471-477.
- doi: 10.31616/asj.2021.0109
Study Design: Retrospective comparative radiological study. Purpose: To analyze the difference in early disc height loss following transforaminal and lateral lumbar interbody fusion (TLIF and LLIF). Overview of Literature: Minimal disc height... -
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- Full-Endoscopic versus Minimally Invasive Lumbar Interbody Fusion for Lumbar Degenerative Diseases : A Systematic Review and Meta-Analysis
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Son S, Yoo BR, Lee SG, Kim WK, Jung JM
- KMID: 2531623
- J Korean Neurosurg Soc.
- 2022 Jul;65(4):539-548.
- doi: 10.3340/jkns.2021.0168
Objective : Although full-endoscopic lumbar interbody fusion (Endo-LIF) has been tried as the latest alternative technique to minimally invasive transforaminal lumbar interobody fusion (MIS-TLIF) since mid-2010, the evidence is still... -
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- Associations Between Trunk Muscle/Fat Composition, Narrowing Lumbar Disc Space, and Low Back Pain in Middle-Aged Farmers: A Cross-Sectional Study
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Baek S, Park Hw, Kim G
- KMID: 2531283
- Ann Rehabil Med.
- 2022 Jun;46(3):122-132.
- doi: 10.5535/arm.21201
Objective To investigate the association of trunk fat and muscle composition, lumbar disc space narrowing, and low back pain in middle-aged farmers. Methods Fat and muscle areas were identified using standard... -
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- Diurnal Variation in Hydration of the Cervical Intervertebral Disc Assessed Using T2 Mapping of Magnetic Resonance Imaging
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Liu C, Wang J, Hou B, Li Y, Morelli JN, Zhang P, Ran J, Li X
- KMID: 2530358
- Korean J Radiol.
- 2022 Jun;23(6):638-648.
- doi: 10.3348/kjr.2021.0950
Objective: The study aimed to investigate the diurnal variation in cervical disc hydration and its relationship with cervical degeneration. Materials and Methods: C3–C7 discs of 86 prospectively enrolled participants (37 males,... -
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- Vertebral Endplate Changes Correlate with Presence of Cartilaginous Endplate in the Herniated Disc Tissue: Factor Predicting Failure of Conservative Treatment
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Latif R, Imran S, Ahmad I, Ilyas MS, Aziz A, Zehra U
- KMID: 2529527
- Asian Spine J.
- 2022 Apr;16(2):212-220.
- doi: 10.31616/asj.2021.0106
Study Design: Cross-sectional comparative. Purpose: To characterize the scores of disc degeneration, inflammation, and nerve density in herniated disc samples and associate findings with the presence of vertebral endplate (VEP) changes... -
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- Current Knowledge and Future Therapeutic Prospects in Symptomatic Intervertebral Disc Degeneration
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Kim JH, Ham CH, Kwon WK
- KMID: 2526552
- Yonsei Med J.
- 2022 Mar;63(3):199-210.
- doi: 10.3349/ymj.2022.63.3.199
Intervertebral disc (IVD) degeneration is the main source of intractable lower back pain, and symptomatic IVD degeneration could be due to different degeneration mechanisms. In this article, we describe the... -
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- Histological Changes of Cervical Disc Tissue in Patients with Degenerative Ossification
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Xiong Y, Yang YL, Gao YS, Wang XM, Yu X
- KMID: 2527175
- J Korean Neurosurg Soc.
- 2022 Mar;65(2):186-195.
- doi: 10.3340/jkns.2021.0082
Objective : To explore the histological feature of the cervical disc degeneration in patients with degenerative ossification (DO) and its potential mechanisms. Methods : A total of 96 surgical segments, from... -
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- Patterns of Lumbar Disc Degeneration: Magnetic Resonance Imaging Analysis in Symptomatic Subjects
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Ruangchainikom M, Daubs MD, Suzuki A, Xiong C, Hayashi T, Scott TP, Phan K, Wang JC
- KMID: 2523380
- Asian Spine J.
- 2021 Dec;15(6):799-807.
- doi: 10.31616/asj.2020.0325
Study Design: Cross-sectional study. Purpose: To evaluate lumbar disc degeneration (LDD) on magnetic resonance imaging (MRI) in symptomatic subjects to accumulate baseline data on the pattern of degeneration. Overview of Literature: LDD... -
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- Effect of Facet Tropism on the Degeneration of the Cervical Facet Joint and Intervertebral Disc
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Chung SS, Park CH, Heo KS
- KMID: 2521201
- J Korean Orthop Assoc.
- 2021 Oct;56(5):413-418.
- doi: 10.4055/jkoa.2021.56.5.413
Purpose: To investigate the effect of facet tropism on the degeneration of facet joint and intervertebral disc in the cervical spine. Materials and Methods: From January 2017 to December 2018, cervical... -
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- Predictors of discogenic pain in magnetic resonance imaging: a retrospective study of provocative discography performed by posterolateral approach
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Jain A, Jain S, Barasker SK, Agrawal A
- KMID: 2520752
- Korean J Pain.
- 2021 Oct;34(4):447-453.
- doi: 10.3344/kjp.2021.34.4.447
Background: Provocative discography (PD) is a test that is useful in diagnosing discogenic pain (DP). In this study, to diagnose DP, we used a posterolateral approach of needle placement and... -
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- The Association Between Sagittal Plane Alignment and Disc Space Narrowing of Lumbar Spine in Farmers
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Park KH, Baek S, Kang EK, Park Hw, Kim G, Kim SH
- KMID: 2519636
- Ann Rehabil Med.
- 2021 Aug;45(4):294-303.
- doi: 10.5535/arm.21037
Objective To investigate whether lumbar lordosis (LL) and lumbar segmental lordosis (LSL) are related to sex, age, low back pain (LBP), and lumbar disc space narrowing (DSN). Methods A total of... -
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- The Relationship between Neural Foraminal Stenosis and Imaging Features of Lumbar Spine MRI in Patients Older Than 60 Years with Lumbar Radiculopathy
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Lee K, Jeong HS, Park C, Kim M, Ryu H, Roh J, Yeom JA, Kim JH, Kim TU, Jeon CH
- KMID: 2518617
- J Korean Soc Radiol.
- 2021 Jul;82(4):862-875.
- doi: 10.3348/jksr.2020.0095
Purpose To investigate the MRI features associated with neural foraminal stenosis (NFS) in patients older than 60 years with lumbar (L) radiculopathy. Materials and Methods This study included 133 retrospectively selected... -
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- The Anti-Inflammatory and Cytoprotective Efficiency of Curvularin, a Fungal Macrolactone against Lipopolysaccharide-Induced Inflammatory Response in Nucleus Pulposus Cells: An In Vitro Study
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Banala RR, Vemuri SK, EV S, AV GR, GPV S
- KMID: 2515008
- Asian Spine J.
- 2021 Apr;15(2):143-154.
- doi: 10.31616/asj.2019.0285
Study Design: Developing an in vitro model for assessing the anti-inflammatory properties of curvularin. Purpose: To evaluate the efficacy of natural fungal macrolactone as a therapeutic drug against lipopolysaccharide (LPS)-induced inflammation... -
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- Mechanical Stimulation and Diameter of Fiber Scaffolds Affect the Differentiation of Rabbit Annulus Fibrous Stem Cells
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Zhou P, Wei B, Guan J, Chen Y, Zhu Y, Ye Y, Meng Y, Guan J, Mao Y
- KMID: 2512638
- Tissue Eng Regen Med.
- 2021 Feb;18(1):49-60.
- doi: 10.1007/s13770-020-00305-0
BACKGROUND: Degeneration of the annulus fibrosus (AF), an important structure of the intervertebral disc, is one of the main causes of degenerative disc disease. Fabrication of scaffolds replicating the stratified... -
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- A New Classification for Cervical Ossification of the Posterior Longitudinal Ligament Based on the Coexistence of Segmental Disc Degeneration
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Lee JK, Ham CH, Kwon WK, Moon HJ, Kim JH, Park YK
- KMID: 2510761
- J Korean Neurosurg Soc.
- 2021 Jan;64(1):69-77.
- doi: 10.3340/jkns.2020.0080
Objective : Classification systems for cervical ossification of the posterior longitudinal ligament (OPLL) have traditionally focused on the morphological characteristics of ossification. Although the classification describes many clinical features associated... -
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- Relevance between Schmorl’s Node and Lumbar Intervertebral Disc Degeneration Quantified with Magnetic Resonance Imaging T2 Mapping in Chronic Low Back Pain
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Ogon I, Takashima H, Morita T, Oshigiri T, Terashima Y, Yoshimoto M, Fukushi R, Fujimoto S, Emori M, Teramoto A, Takebayashi T, Yamashita T
- KMID: 2507906
- Asian Spine J.
- 2020 Oct;14(5):621-628.
- doi: 10.31616/asj.2019.0231
Study Design: Cross-sectional study. Purpose: The purpose of this study was to elucidate the relevance among Schmorl’s node (SN), chronic low back pain (CLBP), and intervertebral disc degeneration (IVDD) with the... -
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- Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
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Rajasekaran S, Soundararajan DCR, Tangavel C, K. S. SVA, Nayagam SM, Matchado MS, Muthurajan R, Shetty AP, Kanna RM, Dharmalingam K
- KMID: 2505234
- Asian Spine J.
- 2020 Aug;14(4):409-420.
- doi: 10.31616/asj.2019.0217
Study Design: Profiling proteins expressed in the nucleus pulposus of fetal intervertebral disc (IVD). Purpose: To evaluate the molecular complexity of fetal IVDs not exposed to mechanical, traumatic, inflammatory, or infective... -
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- Effect of Conditioned Medium from Human Umbilical Cord-Derived Mesenchymal Stromal Cells on Rejuvenation of Nucleus Pulposus Derived Stem/Progenitor Cells from Degenerated Intervertebral Disc
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Zeng X, Lin J, Wu H, Yu J, Tu M, Cheang LH, Zhang J
- KMID: 2504338
- Int J Stem Cells.
- 2020 Jul;13(2):257-267.
- doi: 10.15283/ijsc20027
Background and Objectives: Mesenchymal stromal cells (MSCs)-based treatment for degeneration of intervertebral disc (IVD) has been proposed recently. We here addressed whether MSC secreted factors can rejuvenate nucleus pulposus- derived... -
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