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Association between 14bp Insertion/Deletion Polymorphism in Exon 8 of HLA-G gene and Oral Squamous Cell Carcinoma in Korean Population

Kang SW, Ban JY

  • Int J Oral Biol.
  • 2017 Jun;42(2):79-83.
  • doi: 10.11620/IJOB.2017.42.2.079
Abnormal HLA-G expression occurs in various diseases such as melanoma, renal cell carcinoma, asthma, and classic Hodgkin's lymphoma. The purpose of this study was to determine whether HLA-G gene is...
Development of Refolding Process to Obtain Active Recombinant Human Bone Morphogenetic Protein-2 and its Osteogenic Efficacy on Oral Stem Cells

Lee JH, Jang YJ

  • Int J Oral Biol.
  • 2017 Jun;42(2):71-78.
  • doi: 10.11620/IJOB.2017.42.2.071
BMP-2 is a well-known TGF-beta related growth factor, having a significant role in bone and cartilage formation. It has been employed to promote bone formation in some clinical trials, and...
Development of a Novel Subunit Vaccine Targeting Fusobacterium nucleatum FomA Porin Based on In Silico Analysis

Jeong K, Sao P, Park MJ, Lee H, Kim SH, Rhee JH, Lee SE

  • Int J Oral Biol.
  • 2017 Jun;42(2):63-70.
  • doi: 10.11620/IJOB.2017.42.2.063
Selecting an appropriate antigen with optimal immunogenicity and physicochemical properties is a pivotal factor to develop a protein based subunit vaccine. Despite rapid progress in modern molecular cloning and recombinant...
Action of Mitochondrial Substrates on Neuronal Excitability in Rat Substantia Gelatinosa Neurons

Lee HI, Chun SW

  • Int J Oral Biol.
  • 2017 Jun;42(2):55-61.
  • doi: 10.11620/IJOB.2017.42.2.055
Recent studies indicate that mitochondria are an important source of reactive oxygen species (ROS) in the spinal dorsal horn. In our previous study, application of malate, a mitochondrial electron transport...
Water Extracts of Anthriscus sylvestris Leaf induces Apoptosis in FaDu Human Hypopharynx Squamous Carcinoma Cells

Yang JE, Lee SA, Moon SM, Han SH, Choi YH, Kim SG, Kim DK, Park BR, Kim CS

  • Int J Oral Biol.
  • 2017 Jun;42(2):47-54.
  • doi: 10.11620/IJOB.2017.42.2.047
Anthriscus sylvestris (L.) Hoffm. is a perennial herb found widely distributed in various regions of Korea, Europe, and New Zealand. The root of A. sylvestris have been extensively used in...
Effect of Metformin on Cell Growth and Differentiation in Cultured Odontoblasts

Oh CY, Kim SG, Go DS, Yu SK, Kim TH, Kim CS, Park JC, Kim DK

  • Int J Oral Biol.
  • 2017 Jun;42(2):39-45.
  • doi: 10.11620/IJOB.2017.42.2.039
Metformin (1,1-dimethylbiguanide hydrochloride), derived from French lilac (Galega officinalis), is a first-line anti-diabetic drug prescribed for patients with type 2 diabetes. However, the role of metformin in odontoblastic cell differentiation...

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