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Apoptotic Effects of 6-Gingerol in Human Breast Cancer Cells

Kim HW, Oh DH, Koh JT, Lim YC

  • Int J Oral Biol.
  • 2015 Dec;40(4):223-228.
  • doi: 10.11620/IJOB.2015.40.4.223
6-Gingerol exerts anti-tumor effects in various cancer cell models. We evaluated the effect of 6-gingerol on the growth of MCF-7 breast cancer cells and MCF-10A breast epithelial cells to determine...
Streptococcus mutans Strains Isolated in Korea Can Hardly Metabolize Exogenous Nitric Oxide

Lee HJ, Bang IS

  • Int J Oral Biol.
  • 2015 Dec;40(4):217-221.
  • doi: 10.11620/IJOB.2015.40.4.217
Cariogenic Streptococcus mutans encounters a variety of host defense factors produced in oral cavity. Nitric oxide (NO) and NO-mediated reactive nitrogen species are potential antimicrobials of innate immunity that can...
Ryanodine Receptor-mediated Calcium Release Regulates Neuronal Excitability in Rat Spinal Substantia Gelatinosa Neurons

Park A, Chun SW

  • Int J Oral Biol.
  • 2015 Dec;40(4):211-216.
  • doi: 10.11620/IJOB.2015.40.4.211
Nitric Oxide (NO) is an important signaling molecule in the nociceptive process. Our previous study suggested that high concentrations of sodium nitroprusside (SNP), a NO donor, induce a membrane hyperpolarization...
Development of Quantitative Real-Time PCR Primers for Detection of Prevotella intermedia

Park SN, Kook JK

  • Int J Oral Biol.
  • 2015 Dec;40(4):205-210.
  • doi: 10.11620/IJOB.2015.40.4.205
Prevotella intermedia-specific quantitative real-time PCR (qPCR) primers were previously designed based on the nucleotide sequences of RNA polymerase beta-subunit gene (rpoB). However, the several clinical strains isolated from Korean populations...
MicroRNA-27 Promotes Odontoblast Differentiation via Wnt1 Signaling

Cho JH, Kim SG, Park BS, Go DS, Park JC, Kim DK

  • Int J Oral Biol.
  • 2015 Dec;40(4):197-204.
  • doi: 10.11620/IJOB.2015.40.4.197
MicroRNA (miRNA, miR) is essential in regulating cell differentiation either by inhibiting mRNA translation or by inducing its degradation. However, the role of miRNA in odontoblastic cell differentiation is still...
Effect of Sub-Minimal Inhibitory Concentrations of Antibiotics on Biofilm Formation and Coaggregation of Streptococci and Actinomycetes

Lee SY, Lee SY

  • Int J Oral Biol.
  • 2015 Dec;40(4):189-196.
  • doi: 10.11620/IJOB.2015.40.4.189
Minimal inhibitory concentration (MIC) is the lowest antibiotic concentration that inhibits the visible growth of bacteria. Sub-minimal inhibitory concentration (Sub-MIC) is defined as the concentration of an antimicrobial agent that...
The Influence of Glutaraldehyde Concentration on Electron Microscopic Multiple Immunostaining

Bae JS, Yeo EJ, Bae YC

  • Int J Oral Biol.
  • 2015 Dec;40(4):183-187.
  • doi: 10.11620/IJOB.2015.40.4.183
The present study was aimed to evaluate the influence of glutaraldehyde (GA) concentration on multiple electron microscopic (EM) immunostaining using pre-embedding peroxidase and post-embedding immunogold method. Influence of various concentrations...
Morphological Analysis of the Myelinated Parent Axons that Innervate Rat Upper Molar Pulps in the Trigeminal Ganglion

Paik SK, Kim JH, Kim TH, Bae YC

  • Int J Oral Biol.
  • 2015 Dec;40(4):175-182.
  • doi: 10.11620/IJOB.2015.40.4.175
Previous studies suggested that myelinated axons innervating rat molar pulps undergo morphological changes in their peripheral course. However, little information is available on the morphological feature of the parent axons...
Antimicrobial Effect of Low Temperature Atmospheric Plasma against Oral Pathogens

Kim YM, Choi BB, Park SR, Kim JY, Kim GC

  • Int J Oral Biol.
  • 2015 Dec;40(4):167-173.
  • doi: 10.11620/IJOB.2015.40.4.167
The purpose of this study was to investigate the antibacterial effect of the low temperature atmospheric plasma device with needle tip designed for easy approach to the oral cavity and...
The Centrifugal Influence on Gustatory Neurons in the Nucleus of the Solitary Tract

Cho YK

  • Int J Oral Biol.
  • 2015 Dec;40(4):161-166.
  • doi: 10.11620/IJOB.2015.40.4.161
Neuronal activities of taste-responsive cells in the nucleus of the solitary tract (NST) are affected by various physiological factors, such as blood glucose level or sodium imbalance. These phenomena suggest...

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