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Xylitol Down-Regulates 1alpha,25-Dihydroxy Vitamin D3-induced Osteoclastogenesis via in Part the Inhibition of RANKL Expression in Osteoblasts

Ohk SH, Jeong H, Kim JP, Yoo YJ, Seo JT, Shin DM, Lee SI

  • Int J Oral Biol.
  • 2013 Sep;38(3):127-134.
Xylitol is a sugar alcohol with a variety of functions including bactericidal and anticariogenic effects. However, the cellular mechanisms underlying the role of xylitol in bone metabolism are not yet...
Tumor Necrosis Factor alpha up-regulates the Expression of beta2 Adrenergic Receptor via NF-kappaB-dependent Pathway in Osteoblasts

Baek K, Kang J, Hwang HR, Baek JH

  • Int J Oral Biol.
  • 2013 Sep;38(3):121-126.
Tumor necrosis factor alpha (TNFalpha) is a multifunctional inflammatory cytokine that regulates various cellular and biological processes. Increased levels of TNFalpha have been implicated in a number of human diseases...
Effects of CoCl2 on Osteogenic Differentiation of Human Mesenchymal Stem Cells

Moon YH, Son JW, Moon JS, Kang JH, Kim SH, Kim MS

  • Int J Oral Biol.
  • 2013 Sep;38(3):111-119.
OBJECTIVE: To investigate the effects of the hypoxia inducible factor-1 (HIF-1) activation-mimicking agent cobalt chloride (CoCl2) on the osteogenic differentiation of human mesenchymal stem cells (hMSCs) and elucidate the underlying...
Apoptotic Effects of Co-Treatment with a Chios Gum Mastic and Eugenol on G361 Human Melanoma Cells

Jo JB, Oh SH, Kim IR, Kim GC, Kwak HH, Park BS

  • Int J Oral Biol.
  • 2013 Sep;38(3):101-110.
We investigated the synergistic apoptotic effects of co-treatments with Chios gum mastic (CGM) and eugenol on G361 human melanoma cells. An MTT assay was conducted to investigate whether this co-treatment...
The Role of HS-1200 Induced Autophagy in Oral Cancer Cells

Jang NM, Oh SH, Kim IR, Park HR, Park BS

  • Int J Oral Biol.
  • 2013 Sep;38(3):93-100.
Bile acids and synthetic bile acid derivatives induce apoptosis in various kinds of cancer cells and thus have anticancer properties. Recently, it has been suggested that autophagy may play an...
Quantification of Microstructures in Mice Alveolar Bone using Micro-computed tomography (microCT)

Park HR, Kim HJ, Park BJ

  • Int J Oral Biol.
  • 2013 Sep;38(3):87-92.
Periodontal inflammation increases the risk of tooth loss, particularly in cases where there is an associated loss of alveolar bone and periodontal ligament (PDL). Histological and morphometric evaluation of periodontal...

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