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High-Altitude Cerebral Edema Evaluated with MRI: A Case Report

Hwang S, Lee BH, Hwang YJ, Kim JW

High-altitude cerebral edema (HACE) is a rare life-threatening condition observed in individuals who climb high altitudes. This report describes the case of a 38-year-old man who recently climbed a 5000-m-high...
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Utility of white matter to gray matter signal intensity ratio in comatose patients treated by targeted temperature management after cardiac arrest: a preliminary study

Keum KT, Kim YH, Hwang SY, Lee JH, Lee DW, Song YG, Lee JH, Lee KY

OBJECTIVE: This study examined the efficacy of the white matter (WM) to gray matter (GM) signal intensity ratio (SIR) in predicting the clinical prognosis of cardiac arrest patients. METHODS: Thirty-one patients...
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Three-axis Modification of Coordinates Enables Accurate Stereotactic Targeting in Non-human Primate Brains of Different Sizes

Kim HS, Kang GH, Song H, Kim RG, Park JY, Hwang JH, Kim HI

The brain grows with age in non-human primates (NHPs). Therefore, atlas-based stereotactic coordinates cannot be used directly to target subcortical structures if the size of the animal's brain differs from...
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Association Between Duration of Dysphagia Recovery and Lesion Location on Magnetic Resonance Imaging in Patients With Middle Cerebral Artery Infarction

Kim JH, Oh SH, Jeong HJ, Sim YJ, Kim DG, Kim GC

OBJECTIVE: To investigate association between lesion location on magnetic resonance imaging (MRI) performed after an infarction and the duration of dysphagia in middle cerebral artery (MCA) infarction. METHODS: A videofluoroscopic swallowing...
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An Autopsy Proven Case of CSF1R-mutant Adult-onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) with Premature Ovarian Failure

Kim SI, Jeon B, Bae J, Won JK, Kim HJ, Yim J, Kim YJ, Park SH

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive degenerative white matter disorder caused by mutations in the tyrosine kinase domain of the CSF1R gene. ALSP is...
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Bilateral Lesions in the Posterior Limb of Internal Capsule Attributed to Combination Therapy of Isoniazid and Rifampin

Park MW, Roh J, Im S, Kim MO, Kim YS, Kang J, Kim DH, Kwon OY

Transient isoniazid-induced brain lesions have rarely been reported. The lesions were in the dentate nucleus of cerebellum and thalamus. Meanwhile, the neurotoxicity of rifampin has not been reported evidently. We...
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Toxic Optic Neuropathy Caused by Chlorfenapyr Poisoning

Park SJ, Jung JU, Kang YK, Chun BY, Son BJ

PURPOSE: To report a case of toxic optic neuropathy caused by chlorfenapyr ingestion accompanied by central nervous system involvement. CASE SUMMARY: A 44-year-old female visited our clinic complaining of reduced visual...
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Changes in Diffusion Metrics of the Red Nucleus in Chronic Stroke Patients With Severe Corticospinal Tract Injury: A Preliminary Study

Kim H, Lee H, Jung KI, Ohn SH, Yoo WK

OBJECTIVE: To explore plastic changes in the red nucleus (RN) of stroke patients with severe corticospinal tract (CST) injury as a compensatory mechanism for recovery of hand function. METHODS: The moderate...
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Evaluation of Ataxia in Mild Ischemic Stroke Patients Using the Scale for the Assessment and Rating of Ataxia (SARA)

Choi SW, Han N, Jung SH, Kim HD, Eom MJ, Bae HW

OBJECTIVE: To demonstrate the utility of Scale for the Assessment and Rating of Ataxia (SARA) for evaluation of posterior circulation-related features in patients with mild stroke. METHODS: Forty-five subjects, diagnosed with...
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The Upper Ascending Reticular Activating System between Intralaminar Thalamic Nuclei and Cerebral Cortex in the Human Brain

Jang S, Kwak S

PURPOSE: The ascending reticular activating system (ARAS) is responsible for regulation of consciousness. In this study, using diffusion tensor imaging (DTI), we attempted to reconstruct the thalamocortical projections between the...
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An Experimental Infarct Targeting the Internal Capsule: Histopathological and Ultrastructural Changes

Han CW, Lee KH, Noh MG, Kim JM, Kim HS, Kim HS, Kim RG, Cho J, Kim HI, Lee MC

BACKGROUND: Stroke involving the cerebral white matter (WM) has increased in prevalence, but most experimental studies have focused on ischemic injury of the gray matter. This study was performed to...
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Neurodevelopmental Outcomes According to Brain Injury Patterns in Neonates with Postasphyxial Hypoxic Ischemic Encephalopathy

Jeong SY, Choi SY, Chang YP, Lee YS

PURPOSE: To investigate the relationship between brain injury patterns on magnetic resonance imaging (MRI) and neurodevelopmental outcomes in neonates with postasphyxial hypoxic ischemic encephalopathy (HIE). METHODS: Clinical characteristics and brain MRI...
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White Matter Change Revealed by Diffusion Tensor Imaging in Gliomas

Won YI, Chung CK, Kim CH, Park CK, Koo BB, Lee JM, Jung HW

BACKGROUND: Tumor-related white matter change is detected at late stages with magnetic resonance imaging (MRI), when mass effect or prominent edema is present. We analyzed if diffusion tensor imaging (DTI)...
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Neonatal Seizures Accompanied by Cerebral White Matter Injury Associated with Rotavirus Infection

Kim HA, Jo CK, Kim MJ

PURPOSE: Few studies have investigated the neurological complications of rotavirus infection in newborns. This study reports on clinical characteristics of newborns with seizures during rotavirus infection period and the neurological...
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Prominent Cognitive Dysfunction without Motor Impairment Following Anterior Choroidal Artery Infarction: a Case Report

Park TH, Park J, Park YG, Yoon SY

Neurological deficits commonly associated with anterior choroidal artery infarction (AChAI) include hemiplegia, hemisensory loss, and homonymous hemianopsia, while neuropsychological and perceptual deficits are uncommon. Prominent cognitive function impairment has rarely...
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Association of Dysphagia With Supratentorial Lesions in Patients With Middle Cerebral Artery Stroke

Kim BR, Moon WJ, Kim H, Jung E, Lee J

OBJECTIVE: To determine the supratentorial area associated with poststroke dysphagia, we assessed the diffusion tensor images (DTI) in subacute stroke patients with supratentorial lesions. METHODS: We included 31 patients with a...
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Prolonged Motor Weakness With Syringomyelia in Japanese Encephalitis: A Case Study

Kim YM, Kim Y, Oh J, Kim HR, Park JH

Japanese encephalitis (JE) shows characteristic brain lesions, including bilateral thalamus, midbrain, internal capsule, basal ganglia, and occasionally involves an anterior horn cell. We encountered a case of a 44-year-old man...
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Lack of Myelination in the Anterior Limbs of the Internal Capsule Associated with Cri-du-Chat Syndrome: Case Report

Lee HJ, You SK, Lee SM, Cho HH

A 21-month-old girl with cri-du-chat syndrome in conjunction with developmental delay underwent brain magnetic resonance imaging (MRI). The MRI showed hypoplasia of the brain stem, a normal cerebellum, thinning of...
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Endovascular Treatment in Ruptured Middle Cerebral Artery Dissection Preservation of Arterial Continuity

Nam DH, Park SK

Rupture of spontaneous dissecting aneurysms of the middle cerebral artery (MCA) is rare and its etiology remains obscure, although the risk of rebleeding is greater than with saccular aneurysms. Most...
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Can Predict Late Encephalopathy by Diffusion Tensor Imaging in Acute Phase of Carbon Monoxide Poisoning?

Bang SJ, Kim GT

PURPOSE: Approximately 30% of patients with acute carbon monoxide (CO) poisoning display chronic neurological symptoms due to late encephalopathy, 1/3 in delayed neuropsychiatric sequelae (DNS) and 2/3 in persistent neurological...
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