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Insulin Secretion and Sensitivity during Oral Glucose Tolerance Test in Korean Lean Elderly Women

Kim J, Choi S, Kong B, Oh Y, Shinn S

Impaired glucose tolerance (IGT) and type 2 diabetes including undiagnosed isolated postchallenge hyperglycemia (IPH) are common in the elderly. The aim of this study was to investigate the insulin secretion...
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Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic beta cells

Ma WN, Park SY, Han JS

As glucose is known to induce insulin secretion in pancreatic beta cells, this study investigated the role of a phospholipase D (PLD)-related signaling pathway in insulin secretion caused by high...
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Differences in Insulin Sensitivity and Secretory Capacity Based on OGTT in Subjects with Impaired Glucose Regulation

Rhee SY, Kwon MK, Park BJ, Chon S, Jeong IK, Oh S, Ahn KJ, Chung HY, Kim SW, Kim JW, Kim YS, Woo JT

BACKGROUND: This study examined whether defects in insulin secretion contribute to the development and progression of type 2 diabetes mellitus (T2DM). METHDOS: Plasma insulin and glucose were measured...
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beta-Cell dysfunction and insulin resistance in gestational glucose intolerance

Jang EH, Kwon HS

No abstract available.
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Insulin secretion and insulin resistance in Korean women with gestational diabetes mellitus and impaired glucose tolerance

Yang SJ, Kim TN, Baik SH, Kim TS, Lee KW, Nam M, Park YS, Woo JT, Kim YS, Kim SH

BACKGROUND/AIMS: The aim was to compare the insulin sensitivity and secretion index of pregnant Korean women with normal glucose tolerance (NGT), gestational impaired glucose tolerance (GIGT; only one abnormal value...
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The stimulatory effect of IL-1beta on the insulin secretion of rat pancreatic islet is not related with iNOS pathway

Jeong IK, Oh SH, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

  • KMID: 1093592
  • Exp Mol Med.
  • 2002 Mar;34(1):12-17.
Interleukin 1 (IL-1) is a pleiotropic cytokine with the potential to destroy pancreatic beta-cells, and thought to be involved in the pathogenesis of type I diabetes mellitus. Expression of inducible...
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