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Risk Assessment of Periodontitis according to Metabolic Score for Insulin Resistance in Korean Population: Korea National Health and Nutrition Examination Survey VI (2013–2015)

Kim IH, Lee YC, Kwon YJ, Lee YJ

Background: Studies have reported an association between periodontitis, a chronic inflammatory disease of the periodontal tissues, and insulin resistance. The Metabolic Score for Insulin Resistance (METS-IR) index was recently developed...
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Effects of a Single Bout of High-Intensity Interval Training and Moderate-Intensity Continuous Training on Blood Glucose Homeostasis and Exosome in Young Adults

Kong JY, Kang H

Purpose: The study investigated the effects of a single bout of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on blood glucose homeostasis and exosome levels in young healthy...
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Insulin Fact Sheet in Type 1 and 2 Diabetes Mellitus and Trends of Antidiabetic Medication Use in Insulin Users with Type 2 Diabetes Mellitus: 2002 to 2019

Park J, Kim G, Kim BS, Han KD, Kwon SY, Park SH, Lee YB, Jin SM, Kim JH

Background: This study investigated the trends of insulin use among Korean patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). Changes in prescription of antidiabetic medications...
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Long Non-Coding RNA TUG1 Attenuates Insulin Resistance in Mice with Gestational Diabetes Mellitus via Regulation of the MicroRNA-328-3p/SREBP-2/ERK Axis

Tang X, Qin Q, Xu W, Zhang X

Background: Long non-coding RNAs (lncRNAs) have been illustrated to contribute to the development of gestational diabetes mellitus (GDM). In the present study, we aimed to elucidate how lncRNA taurine upregulated...
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Incretin and Pancreatic β-Cell Function in Patients with Type 2 Diabetes

Ahn CH, Oh TJ, Min SH, Cho YM

To maintain normal glucose homeostasis after a meal, it is essential to secrete an adequate amount of insulin from pancreatic β-cells. However, if pancreatic β-cells solely depended on the blood...
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Predicting the Risk of Insulin-Requiring Gestational Diabetes before Pregnancy: A Model Generated from a Nationwide Population-Based Cohort Study in Korea

Lee SH, Yu J, Han K, Lee SW, You SY, Kim HS, Cho JH, Yoon KH, Kim MK

Background: The severity of gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes. We aimed to generate a risk model for predicting insulin-requiring GDM before pregnancy in Korean women. Methods:...
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Inhibitory Effect of Insulin Treatment on Apoptosis of Intervertebral Disc Cells in a Streptozotocin-Induced Diabetic Rat Model

Kong CG, Park JB, Kim SH

Study Design: Experimental study using a streptozotocin (STZ)-induced diabetic rat model. Purpose: This study aims to investigate whether insulin treatment could attenuate disc cell apoptosis and matrix degradation in a...
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Correspondence on Letter regarding “The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults”

Lee JH, Park K, Lee HS, Park HK, Han JH, Ahn SB

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Correspondence on Editorial regarding “Screening and prediction of nonalcoholic fatty liver disease using a peripheral insulin resistance index: Potential benefits and limitations”

Lee JH, Park K, Lee HS, Park HK, Han JH, Ahn SB

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Letter regarding “The usefulness of metabolic score for insulin resistance for the prediction of incident non-alcoholic fatty liver disease in Korean adults”

Lee HW

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Development and prognosis of hepatocellular carcinoma in patients with diabetes

Nakatsuka T, Tateishi R

The incidence of diabetes mellitus and hepatocellular carcinoma (HCC) has been increasing worldwide during the last few decades, in the context of an increasing prevalence of obesity and non-alcoholic fatty...
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Performance of Fast-Acting Aspart Insulin as Compared to Aspart Insulin in Insulin Pump for Managing Type 1 Diabetes Mellitus: A Meta-Analysis

Dutta D, Mohindra R, Mahajan K, Sharma M

Background: No meta-analysis has analysed efficacy and safety of fast-acting aspart insulin (FIAsp) with insulin pump in type 1 diabetes mellitus (T1DM). Methods: Electronic databases were searched for randomised controlled trials...
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Comparison of Insulin-Treated Patients with Ambiguous Diabetes Type with Definite Type 1 and Type 2 Diabetes Mellitus Subjects: A Clinical Perspective

Laspe I, Meier JJ, Nauck MA

In clinical practice, the distinction between type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) can be challenging, leaving patients with “ambiguous” diabetes type. Insulin-treated patients (n=115) previously...
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Application of Automated Insulin Delivery in Korean Clinical Practice

Jin SM

In contrast to Europe and the United States (US), conventional insulin pumps have not been widely used in East Asia, even among people with type 1 diabetes. Clinical experiences in...
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Effects of the Insulin Therapy Adherence Program for Patients with Type 2 Diabetes: A Randomized Controlled Trial

Park KM, Son JT

Purpose: This study was conducted to evaluate the effects of the insulin therapy adherence program (INSTA GRAM) for patients with type 2 diabetes mellitus. Methods: This study examined a total...
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Handgrip Strength Is Associated with Metabolic Syndrome and Insulin Resistance in Children and Adolescents: Analysis of Korea National Health and Nutrition Examination Survey 2014–2018

Jung HW, Lee J, Kim J

Background: Reduced handgrip strength (HGS) is associated with adverse cardiometabolic health outcomes. We examined HGS, metabolic syndrome (MetS), and insulin resistance (IR) in children and adolescents. Methods: The following population-based data...
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A Case of Hyperinsulinemic Hypoglycemia in Premature Infant Treated with Oral Diazoxide

Pyeon JE, Jeong HR, Koh JW

Neonatal hyperinsulinism, whether permanent or transient, results in prolonged hypoglycemia, which increases the risk of hypoglycemic brain injury. Therefore, prompt diagnosis and management of hyperinsulinemic hypoglycemia is important. Drawing a...
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Relationship between Sleep Duration and Insulin Resistance in Non-Diabetic Korean Adults: The Korea National Health and Nutrition Examination Survey, 2019–2020

Park S, Choi CJ

Background: Several recent studies demonstrated that inadequate sleep duration increases the risk of various chronic diseases such as type 2 diabetes, obesity, and metabolic syndrome. Therefore, the importance of sleep...
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Resistance exercise training‑induced skeletal muscle strength provides protective effects on high‑fat‑diet‑induced metabolic stress in mice

Kim H, Kim Y, Kim I, Seong J

Background: Resistance exercise training is known to improve metabolic disorders, such as obesity and type2 diabetes. In this study, we investigated whether the beneficial effects of resistance exercise training persisted...
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Exploring differentially expressed genes related to metabolism by RNASeq in porcine embryonic fibroblast after insulin treatment

Liang Y, Wang J, Li X, Wu S, Jiang C, Wang Y, Li X, Liu ZH, Mu Y

Background: Insulin regulates glucose homeostasis and has important effects on metabolism, cell growth, and differentiation. Depending on the cell type and physiological context, insulin signal has specific pathways and biological...
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