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Feasibility and efficacy of modern minilaparoscopy with 2.9 mm laparoscope for diagnostic and level II gynaecological procedure

Rai R, Roy KK, Nair V, Kachhawa G, Zangmo R, Garg D, Vanamail P

Objective Laparoscopy has now become a state-of-the-art technique for many diagnostic and therapeutic procedures with known advantages over laparotomy. There is scarce literature from India regarding minilaparoscopy, as per our...
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A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility

Agarwal A, Finelli R, Selvam MKP, Leisegang K, Majzoub A, Tadros N, Ko E, Parekh N, Henkel R, Durairajanayagam D, Colpi GM, Cho CL, Sallam HN, Park HJ, Saleh R, Micic S, Ambar RF, Zini A, Tremellen K, Alvarez JG, Palani A, Arafa M, Gava MM, Jindal S, Amar E, Kopa Z, Moein MR, Busetto GM, Sengupta P, Kavoussi P, Maldonado I, Fikri J, Borges Jr. E, Martinez M, Bojovic D, Rajmil O, Aydos K, Parekattil S, Marmar JL, Sefrioui O, Jungwirth A, Rodriguez Peña MG, Cordts EB, Elbardisi H, Mostafa T, Sabbaghian M, Gilani MAS, Morimoto Y, Alves MG, Spasic A, Kenic U, Ramsay J, Akande EO, Oumeziane A, Dozortsev D, Chung E, Bell E, Allegra A, Tanos V, Fiadjoe M, Gurgan T, Michel AA, Hazem AR, Oborna I, Arab H, Esteves S, Amer M, Kadioglu A, Yuzko O, Korsak V, Shah R

Purpose: The use of antioxidants is common practice in the management of infertile patients. However, there are no established guidelines by professional societies on antioxidant use for male infertility. Materials and...
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Evaluation of SARS-CoV-2 in Human Semen and Effect on Total Sperm Number: A Prospective Observational Study

Best JC, Kuchakulla M, Khodamoradi K, Lima TFN, Frech FS, Achua J, Rosete O, Mora B, Arora H, Ibrahim E, Ramasamy R

Purpose: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has created a surge of research to help better understand the breadth of possible sequelae. However, little is known regarding...
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The Use of Testicular Sperm for Intracytoplasmic Sperm Injection in Patients with High Sperm DNA Damage: A Systematic Review

Ambar RF, Agarwal A, Majzoub A, Vij S, Tadros NN, Cho CL, Parekh N, Borges Jr. E, Glina S

The advent of intracytoplasmic sperm injection (ICSI) has changed the human reproduction landscape by overcoming several limitations related to both male and female infertility factors. However, despite the development of...
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Coenzyme Q10, oxidative stress markers, and sperm DNA damage in men with idiopathic oligoasthenoteratospermia

Alahmar AT, Sengupta P, Dutta S, Calogero AE

Objective: Oxidative stress (OS) plays a key role in the etiology of unexplained male infertility. Coenzyme Q10 (CoQ10) is a potent antioxidant that may improve semen quality and OS in...
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Coenzyme Q10, oxidative stress, and male infertility: A review

Alahmar AT, Calogero AE, Singh R, Cannarella R, Sengupta P, Dutta S

Male infertility has a complex etiopathology, which mostly remains elusive. Although research has claimed that oxidative stress (OS) is the most likely underlying mechanism of idiopathic male infertility, the specific...
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Effect of phosphodiesterase type 5 inhibitors on sperm motility and acrosome reaction: An in vitro study

Song SH, Shin DH, Her YS, Oh MH, Baek JW, Sung S, Eum JH, Heo Y, Kim DS

Purpose: Phosphodiesterase type 5 (PDE5) inhibitors are effective treatments for erectile dysfunction, and several recent studies have reported positive effects of PDE5 inhibitors on semen parameters as well. However, the...
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Effects of Mind–Body Programs on Infertile Women: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Ha JY, Ban SH

Purpose: This study was to systematically review randomized controlled trials and conduct a meta analysis. The results of randomized controlled trials were integrated and analyzed to assess the effects of...
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The clinical outcomes of fresh versus frozen embryos transfer in women ≥40 years with poor ovarian response

Liu C, Li Y, Jiang H, Liu Y, Song X

Objective To compare the clinical outcomes of fresh embryo transfers (ETs) and frozen-thawed embryo transfers (FETs) after a freeze-all cycle in women ≥40 years old with poor ovarian response (POR). Methods...
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Physical Activity and Successful Pregnancy in 6 Months: A Finding from the Pregnancy and Urban Environment Study

An SM, Choe SA, Jun B

Purpose: This study aimed to assess the association between physical activity and pregnancy in 6 months among infertile women who underwent in vitro fertilization (IVF). Methods: The participants included in this...
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Survey of Microsurgery Training Availability in US Urology Residency Programs

Masterson TA, Nackeeran S, Rainer Q, Hauser N, Marcovich R, Ramasamy R

Purpose: The Accreditation Council of Graduate Medical Education (ACGME) establishes surgical minimum numbers of cases for urologic training. Currently there is not a requirement for microsurgery, likely from a belief...
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Coenzyme Q10 Improves Sperm Parameters, Oxidative Stress Markers and Sperm DNA Fragmentation in Infertile Patients with Idiopathic Oligoasthenozoospermia

Alahmar AT, Calogero AE, Sengupta P, Dutta S

Purpose: Oxidative stress and sperm DNA fragmentation (SDF) are potential contributing factors for idiopathic male infertility. Coenzyme Q10 (CoQ10) have been reported to be effective in the treatment of idiopathic...
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A Novel Approach to Improving the Reliability of Manual Semen Analysis: A Paradigm Shift in the Workup of Infertile Men

Douglas C, Parekh N, Kahn LG, Henkel R, Agarwal A

Conventional semen analysis (SA) is an essential component of the male infertility workup, but requires laboratories to rigorously train and monitor technicians as well as regularly perform quality assurance assessments....
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Protein Fingerprinting of Seminal Plasma Reveals Dysregulation of Exosome-Associated Proteins in Infertile Men with Unilateral Varicocele

Selvam MKP, Agarwal A, Sharma R, Samanta L, Gupta S, Dias TR, Martins AD

Purpose: Aberrant expression of seminal plasma proteins are associated with altered homeostasis that may affect the fertilizing ability of spermatozoa. However, the precise roles of seminal exosomes on sperm function...
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An In-Depth Bibliometric Analysis and Current Perspective on Male infertility Research

Baskaran S, Agarwal A, Leisegang K, Pushparaj PN, Selvam MKP, Henkel R

Purpose: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to...
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Sperm retrieval by conventional testicular sperm extraction for assisted reproduction in patients with Zinner syndrome

Cito G, Gemma L, Giachini C, Micelli E, Cocci A, Fucci R, Picone R, Sforza S, Nesi G, Santi R, Minervini A, Masieri L, Carini M, Coccia ME, Natali A

We present data from three Caucasian men with Zinner syndrome who attended our center for the treatment of primary couple’s infertility. Each patient was scheduled for conventional testicular sperm extraction...
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Histopathology and Ultrastructural Findings of Fatal COVID-19 Infections on Testis

Achua JK, Chu KY, Ibrahim E, Khodamoradi K, Delma KS, Iakymenko OA, Kryvenko ON, Arora H, Ramasamy R

Purpose: To evaluate the presence and analyze the pathological changes within the testes of patients who died or recovered from severe acute respiratory syndrome coronavirus 2 (COVID-19) complications. Materials and Methods:...
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Hepatitis B Surface Antigen Seropositive Men in Serodiscordant Couples: Effects on the Assisted Reproductive Outcomes

Cito G, Coccia ME, Fucci R, Picone R, Cocci A, Sessa M, Sessa F, Rizzello F, Micelli E, Trotta M, Badolato L, Campi R, Criscuoli L, Serni S, Carini M, Natali A

Purpose: To evaluate the influence of hepatitis B virus (HBV) infection in men of serodiscordant couples on the reproductive outcomes. Materials and Methods: A total of 134 infertile couples were included...
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Proteomic Profiling of Seminal Plasma Proteins in Varicocele Patients

Panner Selvam MK, Agarwal A

Purpose: Seminal plasma provides a nutritive and protective milieu for spermatozoa. It contains factors/proteins required for sperm maturation, hyperactivation, capacitation and acrosome reaction. Alteration in the expression levels of seminal...
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Comparison of the deleterious effects of yaji and cadmium chloride on testicular physiomorphological and oxidative stress status: The gonadoprotective effects of an omega-3 fatty acid

Ekhoye EI, Olerimi SE, Ehebha SE

Objective This study investigated testicular oxidative stress status and physiomorphological function in Wistar rats fed with yaji and cadmium chloride (CdCl2). Methods: Sixty male albino Wistar rats (12 per group) were...
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