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Apoptosis of Alveolar Cells in Pneumocystis Carinii Pneumonia: Application of Electron Microscopic Terminal Deoxynucleotidyl Transferase-Mediated dUTP-Biotin Nick End Labeling Method

Kang KH, Kim SP, Kwon KY

  • KMID: 2275589
  • Korean J Pathol.
  • 2001 Dec;35(6):496-505.
BACKGROUND: Pneumocystis carinii (P. carinii) attaches to alveolar cells and causes injury to the epithelial cells by direct toxic effects or inhibition of epithelial growth and replication. Although respiratory cell...
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Terminal Deoxynucleotidyl Transferase-Mediated Deoxyuridine Triphosphate Nick End Labeling (TUNEL) Assay to Characterize Histopathologic Changes Following Thermal Injury

Lee JM, Park JH, Kim BY, Kim IH

BACKGROUND: Despite the wide application of lasers and radiofrequency (RF) surgery in dermatology, it is difficult to find studies showing the extent of damage dependent on cell death. OBJECTIVE: We evaluated...
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Effects of Posttraumatic Hypothermia in an Animal Model of Traumatic Brain Injury(TBI): Immunohistochemical Stain by TUNEL & beta-APP

An BK, Ha YS, Hyun DK, Park CO, Kim JM

  • KMID: 1547545
  • J Korean Neurosurg Soc.
  • 2000 Apr;29(4):461-470.
No abstract available.
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Apoptotic Keratinocytes in Acrodermatitis Enteropathica

Park YL, Whang KU, Bang SW, Kim YK, Yu HJ, Son SJ

  • KMID: 1891506
  • Korean J Dermatol.
  • 1996 Oct;34(5):753-756.
BACKGROUND: The cause of acrodermatitis enteropathica(AE) is closely related to zinc deficiency. Zinc is a potent inhibitor of endonuclease. Acute rises in the apoptosis in lymphoid and myeloid cell lines...
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Altered Cellular Kinetics in Growth Plate according to Alterations in Weight Bearing

Park H, Kong SY, Kim HW, Yang IH

PURPOSE: To examine the effects of change in weight bearing on the growth plate metabolism, a simulated animal model of weightlessness was introduced and the chondrocytes' cellular kinetics was evaluated. MATERIALS...
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Role of Apoptosis in the Differentiation of the Parietal Epithelium of the Renal Corpuscle in the Developing Rat Kidney

Lee SH, Kim YH, Kim WY, Cha JH, Kim J, Jung JW

  • KMID: 2224607
  • Korean J Anat.
  • 1997 Dec;30(6):673-682.
The purpose of this study was to establish the role of apoptosis in the developing renal corpuscle in the prenatal rat kidney. Kidneys from 14-, 16-, 18-, and 20-day-old fetuses[E-14,...
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Study of Detection Method of Apoptosis in Colorecteal Cancer Tissue

Kim KH, Shim KS, Kim SS, Koo H, Park EB

OBJECTIVES: Apoptosis is a specific mode of cell death recognized by a characteristic pattern of morphological, biochemical, and molecular changes, There are several methods of detection of apoptosis. Morphological changes...
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Evaluation of Hematopoietic Abnormalities and Apoptosis in Myelodysplastic Syndromes Using Long Term Bone Marrow Culture System and In Situ Nick End Labeling Method

Won JH, Hong DS, Park HS, Lee JS

  • KMID: 2251588
  • Korean J Med.
  • 1997 Oct;53(4):469-481.
OBJECTIVES: The myelodysplastic syndromes (MDS) are a group of acquired clonal hematopoietic disorders characterized by peripheral cytopenias and a hypercellular or normocellular dysplastic bone marrow. The mechanisms responsible for development...
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The Apoptotic Labeling Index of Parathyroid Tissue in Patients with the Secondary Hyperparathyroidism of End Stage Renal Disease

Lee YM, Lee JB

PURPOSE: The cause of renal hyperparathyroidism is unclear and the role of hyperphosphatamia is the only well established cause of renal osteodystrophy. The long life span of the parathyroid cells...
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Placental Apoptosis in Preeclampsia

Choi WJ, Shin JG, Choi WS, Lee JH, Paik WY

  • KMID: 1613421
  • Korean J Perinatol.
  • 2002 Sep;13(3):267-273.
OBJECTIVE: To investigate the change of placental apoptosis and the expression of their mediator in preeclampsia women. METHODS: Placental tissues from 10 cases of preeclampsia and 15 cases of normal pregnancy...
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Apoptotic Neuronal Death in the Mouse Brain Induced by Experimental Japanese Encephalitis Virus Infection

Kang TH, Chae SL, Choi WY, Park C, Nam JH, Joo YR, Park KY

  • KMID: 2030784
  • Korean J Anat.
  • 2005 Jun;38(3):259-264.
Japanese encephalitis virus (JEV)may cause acute encephalitis in humans and induce severe cytopathic effects in various types of cultured cells. To investigate whether JEV infection induces apoptosis, we examined DNA...
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Apoptotic Cell Death in Experimental Retinal Vein Occlusion

Kang SG, Chung H

  • KMID: 2336899
  • J Korean Ophthalmol Soc.
  • 2000 Mar;41(3):576-584.
We used an animal model of laser-induced retinal vein occlusion to study the temporal and spatial patterns of neuronal necrosis and apoptosis. After photodynamic retinal vein thrombosis with argon-green laser,...
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The Effects of Amniotic Membrane Ointment Application on Photore fractive Keratectomized Cornea in Rabbits

Lee DY, Park WC, Rho SH

  • KMID: 2127734
  • J Korean Ophthalmol Soc.
  • 2000 Oct;41(10):2069-2077.
The authors investigated the effects of amniotic membrane ointment on inflammatory cell infiltration into corneal stroma, early keratocyte and inflammatory cell apoptosis and lipid peroxidation of cell membrane after photorefractive...
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Apoptosis in dilated cardiomyopathy

Hong BK, Kwon HM, Byun KH, Kim D, Choi EY, Kang TS, Kang SM, Chun KJ, Jang Y, Kim HS

  • KMID: 759491
  • Korean J Intern Med.
  • 2000 Jan;15(1):56-64.
OBJECTIVE: Cardiomyopathy, a popular diagnosis that always obscures more than it reveals, nevertheless has several characteristic histological features. These prominently include widespread focal myocardial fibrosis and associated hypertrophy of surviving...
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Protective Effect of Heat Shock Protein 70 Against Oxidative Stresses in Human Corneal Fibroblasts

Kim YS, Han JA, Cheong TB, Ryu JC, Kim JC

We evaluated DNA protection effect of heat shock protein (HSP) against cytotoxic effects of exogenous nitric oxide (NO) and reactive oxygen intermediate (ROI). Cultured human corneal fibroblasts were divided into...
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Protective Effect of Ketamine on DNA Fragmentation in Astroglial Ischemic Model: Use of the TUNEL Assay to Determine Apoptosis

Kim MH, Lee JJ

BACKGROUND: Ketamine, a dissociative anesthetic, was known to be beneficial in reducing neuronal or astroglial damage by anoxic or ischemic insults. Detection of DNA fragments in situ using the terminal...
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Effects of Electrical Stimulation on Muscle Apoptosis in Spinal Cord Injury Rabbit Model: A preliminary study

Lee HJ, Bang MS, Kim DY, Kim SJ, Han TR

  • KMID: 2324432
  • J Korean Acad Rehabil Med.
  • 2007 Feb;31(1):85-91.
OBJECTIVE: To determine the effect of functional electrical stimulation (FES) in the paralyzed muscles of rabbits with spinal cord injury (SCI). METHOD: Fifteen male New Zealand white rabbits were injured by...
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Effects of Brain Death on the Myocardium in Canine Brain Death Models

Cho MC, Nam GB, Kim DW, Kim SS

BACKGROUND: Clinical and experimental studies have suggested that brain death may cause hemodynamic, electrocardiographic, functional or histopathologic changes of the heart. METHODS: Brain death was induced by increasing intracranial pressure(ICP) abruptly...
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Correlation Between the Frequency of Apoptotic Bodies and Gleason Scores in Prostatic Cancer

Yoon HS, Kim HJ, Koo HS, Kim OK, Kim SS

  • KMID: 2073680
  • Korean J Pathol.
  • 1997 May;31(5):462-469.
Apoptosis (or programmed cell death) is defined by morphologic changes induced by a spectrum of physical and chemical agents. resulting in non-pathologic cell loss, which is relevant to a range...
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The effect of oxygen on retinal degeneration in wild-type and hsp70.1 knockout neonatal retinal degeneration mice

Choi MY, Yu YS, Kim SK, Kim YJ, Seo JS

The present study examined the effect of oxygen on photoreceptor degeneration in the retina of heat shock protein 70.1 (hsp70.1) knockout type and wild-type retinal degeneration (rd) mice. All the...
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