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Immune checkpoint blockade therapy for bladder cancer treatment

Kim J

Bladder cancer remains the most immunogenic and expensive malignant tumor in the United States today. As the 4th leading cause of death from cancer in United States, Immunotherapy blocking immune...
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Strategies to Improve Dendritic Cell-based Immunotherapy against Cancer

Song SY, Kim HS

Dendritic cells (DCs) play a pivotal role in T cell-mediated immunity and have been shown to induce strong antitumor immune responses in vitro and in vivo. Various approaches utilizing different...
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Immunotherapy of Malignant Melanoma with Tumor Lysate-Pulsed Autologous Monocyte-Derived Dendritic Cells

Kim DS, Kim DH, Goo B, Cho YH, Park JM, Lee TH, Kim HO, Kim HS, Lee H, Lee JD, Byamba D, Je JH, Lee MG

PURPOSE: Dendritic cell (DC) vaccination for melanoma was introduced because melanoma carries distinct tumor-associated antigens. The purpose of this study was to investigate the efficacy and safety of DC vaccination...
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Inhibition of Lewis Lung Carcinoma Growth by Toxoplasma gondii through Induction of Th1 Immune Responses and Inhibition of Angiogenesis

Kim JO, Jung SS, Kim SY, Kim TY, Shin DW, Lee JH, Lee YH

Toxoplasma gondii is an obligate intracellular protozoan parasite that induces antitumor activity against certain types of cancers. However, little information is available regarding the immunologic mechanisms that regulate these effects....
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Recent Advances in Toxoplasma gondii Immunotherapeutics

Lim SS, Othman RY

Toxoplasmosis is an opportunistic infection caused by the protozoan parasite Toxoplasma gondii. T. gondii is widespread globally and causes severe diseases in individuals with impaired immune defences as well as...
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Prominent IL-12 Production and Tumor Reduction in Athymic Nude Mice after Toxoplasma gondii Lysate Antigen Treatment

Pyo KH, Jung BK, Xin CF, Lee YW, Chai JY, Shin EH

Toxoplasma gondii is an intracellular protozoan parasite that causes a Th1 cellular immunity. Our previous study showed that T. gondii lysate antigen (TLA) treatment in S180 tumor-bearing mice resulted in...
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