- Mesenchymal Stem Cell Therapy in Acute Liver Failure
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Wang YH, Chen EQ
- KMID: 2546010
- Gut Liver.
- 2023 Sep;17(5):674-683.
- doi: 10.5009/gnl220417
Acute liver failure (ALF) is a severe liver disease syndrome with rapid deterioration and high mortality. Liver transplantation is the most effective treatment, but the lack of donor livers and... -
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- Applications of Bioinspired Platforms for Enhancing Immunomodulatory Function of Mesenchymal Stromal Cells
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Kim OH, Jeon TJ, So YI, Shin YK, Lee HJ
- KMID: 2545225
- Int J Stem Cells.
- 2023 Aug;16(3):251-259.
- doi: 10.15283/ijsc22211
Mesenchymal stromal cells (MSCs) have attracted scientific and medical interest due to their self-renewing properties, pluripotency, and paracrine function. However, one of the main limitations to the clinical application of... -
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- Immunomodulation for Tissue Repair and Regeneration
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Moon S, Hong J, Go S, Kim BS
- KMID: 2542959
- Tissue Eng Regen Med.
- 2023 Jun;20(3):389-409.
- doi: 10.1007/s13770-023-00525-0
Various immune cells participate in repair and regeneration following tissue injury or damage, orchestrating tissue inflammation and regeneration processes. A deeper understanding of the immune system’s involvement in tissue repair... -
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- In vitro effects of monophosphoryl lipid A and Poly I:C combination on equine cells
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Lee DH, Lee Eb, Seo Jp, Ko EJ
- KMID: 2542989
- J Vet Sci.
- 2023 May;24(3):e37.
- doi: 10.4142/jvs.23007
Background: Toll-like receptor (TLR) agonists have been used as adjuvants to modulate immune responses in both animals and humans. Objectives: The objective of this study was to evaluate the combined effects... -
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- Gut Microbial Metabolites on Host Immune Responses in Health and Disease
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Yoon JH, Do JS, Velankanni P, Lee CG, Kwon HK
- KMID: 2544661
- Immune Netw.
- 2023 Feb;23(1):e6.
- doi: 10.4110/in.2023.23.e6
Intestinal microorganisms interact with various immune cells and are involved in gut homeostasis and immune regulation. Although many studies have discussed the roles of the microorganisms themselves, interest in the... -
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- Long-term treatment of allogeneic adipose-derived stem cells in a dog with rheumatoid arthritis
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Seo MG, Park S, Han S, Kim AY, Lee EJ, Jeong KS, Hong IH
- KMID: 2532290
- J Vet Sci.
- 2022 Jul;23(4):e61.
- doi: 10.4142/jvs.22069
Background: Although there are growing demands for stem cell-based therapy for companion animals in various diseases, a few clinical trials have been reported. Moreover, most of them are the results... -
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- Clinical importance of immunonutrition in infants: a review of the recent literature
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Park JS
- KMID: 2531357
- Clin Exp Pediatr.
- 2022 Jul;65(7):337-343.
- doi: 10.3345/cep.2021.00570
During the last decades, the role of nutrition has been well elucidated in medicine, especially among critically ill infants and children. Many nutrients have the potential to modulate the immune... -
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- Diesel Exhaust Particles Impair Therapeutic Effect of Human Wharton’s Jelly-Derived Mesenchymal Stem Cells against Experimental Colitis through ROS/ERK/cFos Signaling Pathway
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Park HS, Oh MK, Lee JW, Chae DH, Joo H, Kang JY, An HB, Yu A, Park JH, Yoo HM, Jung HJ, Choi U, Jung JW, Kim IS, Oh IH, Yu KR
- KMID: 2529835
- Int J Stem Cells.
- 2022 May;15(2):203-216.
- doi: 10.15283/ijsc21178
Background and Objectives: Epidemiological investigations have shown positive correlations between increased diesel exhaust particles (DEP) in ambient air and adverse health outcomes. DEP are the major constituent of particulate atmospheric... -
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- Molecular Characteristics and Potent Immunomodulatory Activity of Fasciola hepatica Cystatin
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Zhang K, Liu Y, Zhang G, Wang X, Li Z, Shang Y, Ning C, Ji C, Cai X, Xia X, Qiao J, Meng Q
- KMID: 2529674
- Korean J Parasitol.
- 2022 Apr;60(2):117-126.
- doi: 10.3347/kjp.2022.60.2.117
Cystatin, a cysteine protease inhibitor found in many parasites, plays important roles in immune evasion. This study analyzed the molecular characteristics of a cystatin from Fasciola hepatica (FhCystatin) and expressed... -
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- The Immunomodulating Effects of Thalidomide and Dexamethasone in a Murine Cardiac Allograft Transplantation Model
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Kim SJ, Kim JY, Kim EJ, Lee H, Cho Y, Kim MS, Kim YS, Kim BS, Huh KH
- KMID: 2525259
- Yonsei Med J.
- 2022 Feb;63(2):158-165.
- doi: 10.3349/ymj.2022.63.2.158
Purpose: The immunomodulatory effects of thalidomide (TM) and dexamethasone (DX) on immune cells and their co-stimulatory, co-inhibitory molecules in vitro and in vivo have been previously reported. The current study... -
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- Immunosuppression and Neuroinflammation in Stroke Pathobiology
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Jiang Q, Stone CR, Elkin K, Geng X, Ding Y
- KMID: 2515810
- Exp Neurobiol.
- 2021 Apr;30(2):101-112.
- doi: 10.5607/en20033
Over the preceding decades, there have been substantial advances in our knowledge of the pathophysiology of stroke. One such advance has been an increased understanding of the multifarious crosstalk in... -
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- Effect of pregabalin on nociceptive thresholds and immune responses in a mouse model of incisional pain
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Park JH, Cho SH, Kim R, Na SH, Kang Es, Yeom My, Jang Y
- KMID: 2514418
- Korean J Pain.
- 2021 Apr;34(2):185-192.
- doi: 10.3344/kjp.2021.34.2.185
Background: It is known that some analgesics as well as pain can affect the immune system. The aim of this study was to investigate the analgesic effect and immunomodulation of... -
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- Systemic Immunomodulatory Effects of Combinatorial Treatment of Thalidomide and Dexamethasone on T Cells and Other Immune Cells
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Kim EJ, Kim JY, Choi HY, Lee H, Lee J, Kim MS, Kim YS, Huh KH, Kim BS
- KMID: 2512428
- Yonsei Med J.
- 2021 Feb;62(2):137-148.
- doi: 10.3349/ymj.2021.62.2.137
Purpose In organ transplantation, the need for immune modulation rather than immune suppression has been emphasized. In this study, we investigated whether combinatorial treatments of with thalidomide (TM) and dexamethasone (DX)... -
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- Vaccines and Treatment of Coronavirus Disease 2019
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Choe PG
- KMID: 2509481
- Korean J Med.
- 2020 Dec;95(6):364-369.
- doi: 10.3904/kjm.2020.95.6.364
In December 2019, a new strain of betacoronavirus, severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19), emerged in Wuhan, China. Subsequently, the virus quickly spread worldwide... -
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- Effectiveness of Intravenous Immunoglobulin Therapy for Pediatric Viral Encephalitis
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Byun JE, Lee KY
- KMID: 2506912
- Ann Child Neurol.
- 2020 Oct;28(4):145-155.
- doi: 10.26815/acn.2020.00164
Purpose: Intravenous immunoglobulin (IVIg) is considered as a first-line therapy for autoimmune encephalitis. However, its effectiveness in viral encephalitis has yet to be evaluated. Therefore, we investigated the effectiveness of... -
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- Arthrospira (Spirulina) platensis Attenuates Dextran Sulfate Sodium-induced Colitis in Mice by Suppressing Key Pro-inflammatory Cytokines
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Garcia FAdO, Sales-Campos H, Yuen VG, Machado JR, Viana GSdB, Oliveira CJF, McNeill JH
- KMID: 2506671
- Korean J Gastroenterol.
- 2020 Sep;76(3):150-158.
- doi: 10.4166/kjg.2020.76.3.150
Background/Aims: Therapies aimed at modulating cytokines have been used to treat inflammatory illnesses, such as inflammatory bowel disease. On the other hand, patients may become intolerant, refractory, or present with... -
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- SOCS1 Regulates the Immunomodulatory Roles of MSCs on B Cells
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Zhang L, Qu YN, Zhang HY, Wu ZY, Li ZL, Guo WB, Wang QB, Fang NZ, Jiang XX
- KMID: 2504336
- Int J Stem Cells.
- 2020 Jul;13(2):237-245.
- doi: 10.15283/ijsc20001
Background and Objectives: The effective use of MSCs for the treatment of some B cell-mediated immune diseases is quite limited. The main reason is that the immunomodulatory effects of mesenchymal... -
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- Mesenchymal Stem Cell-Derived Exosomes: A Promising Therapeutic Ace Card to Address Autoimmune Diseases
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Baharlooi , Azimi M, Salehi Z, Izad M
- KMID: 2500563
- Int J Stem Cells.
- 2020 Mar;13(1):13-23.
- doi: 10.15283/ijsc19108
With the development of novel treatments for autoimmune disorders, it has become a popular research focus which mesenchymal stem cells (MSCs) have the capacity to counteract with autoimmune diseases progression.... -
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- Protective Effect of Sphaerococcus coronopifolius Crude Extract in Combination with Bacillus Calmette-Guerin on Ligature-Induced Depression in Female Wistar Rats
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Fellah F, Djenidi R, Chebout I
- KMID: 2501488
- Psychiatry Investig.
- 2020 Feb;17(2):130-139.
- doi: 10.30773/pi.2019.0234
Objective Immunomodulation is a therapeutic technique that modulates the balance of cytokines in the body. In this regard, our experiment was conducted to investigate the potential effect of S. coronopifolius... -
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- Neuroinflammation after Intracerebral Hemorrhage and Potential Therapeutic Targets
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Tschoe C, Bushnell C, Duncan PW, Alexander-Miller MA, Wolfe SQ
- KMID: 2500917
- J Stroke.
- 2020 Jan;22(1):29-46.
- doi: 10.5853/jos.2019.02236
Spontaneous intracerebral hemorrhage (ICH) is a catastrophic illness causing significant morbidity and mortality. Despite advances in surgical technique addressing primary brain injury caused by ICH, little progress has been made... -
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