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Clinical features of elderly chronic urticaria

Ban GY, Kim MY, Yoo HS, Nahm DH, Ye YM, Shin YS, Park HS

BACKGROUND/AIMS: Chronic urticaria (CU) is defined as itchy wheals lasting 6 weeks or more. As the aged population increases worldwide, it is essential to identify the specific features of this...
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Longitudinal study of specific antibodies to toluene diisocyanate (TDI)-human serum albumin (HSA) conjugate in patients with TDI-induced asthma

Park HS, Lee SK, Lee YM, Kim SS, Nahm DH

  • KMID: 759619
  • Korean J Intern Med.
  • 2002 Dec;17(4):249-251.
BACKGROUND: An appreciable number of patients with toluene diisocyanate (TDI)-induced asthma have high serum levels of specific IgE (sIgE) antibody to TDI-human serum albumin conjugate (HSA). A recent investigation...
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Different Responses in Induction of Allergen Specific Immunoglobulin G4 and IgE-Blocking Factors for Three Mite Subcutaneous Immunotherapy Products

Park KH, Lee SC, Son YW, Jeong KY, Shin YS, Shin JU, Sim DW, Park HJ, Lee JH, Lee KH, Park JW

PURPOSE: Specific immunoglobulin G4 (sIgG4) and immunoglobulin E (IgE)-blocking factors produced by subcutaneous immunotherapy (SCIT) play a critical role in the induction of allergen tolerance. However, comparative studies of available...
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Changes of Serum Cytokines After the Long Term Immunotherapy with Japanese Hop Pollen Extracts

Ye YM, Lee SK, Kim SH, Nahm DH, Suh CH, Park HS

Japanese hop (Hop J) pollen has been considered as one of the major causative pollen allergens in the autumn season. We developed a new Hop J immunotherapy extract in collaboration...
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Effect of German chamomile oil application on alleviating atopic dermatitis-like immune alterations in mice

Lee SH, Heo Y, Kim YC

Historically, German chamomile (GC) oil has been used for treatment of skin disorders. BALB/c mice were sensitized twice a week with 100 microL of 1% 2,4-dinitrochlorobenzene (DNCB) and challenged twice...
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Standardization of Weed Pollen Extracts, Japanese Hop and Mugwort, in Korea

Jeong KY, Son M, Choi SY, Park KH, Park HJ, Hong CS, Lee JH, Park JW

PURPOSE: Japanese hop (Humulus spp.) and mugwort (Artemisia spp.) are notable causes of autumn pollinosis in East Asia. However, Japanese hop and mugwort pollen extracts, which are widely used for...
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Identification of Dioscorea Batatas (Sanyak) Allergen as an Inhalant and Oral Allergen

Hur GY, Park HJ, Kim HA, Ye YM, Park HS

Dioscorea batatas is widely used in Asia as a herbal medicine or food product with potential health benefits. There have been several reports of occupational asthma caused by inhalation of...
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Identifying Genetic Susceptibility to Sensitization to Cephalosporins in Health Care Workers

Nam YH, Kim JE, Kim SH, Jin HJ, Hwang EK, Shin YS, Ye YM, Park HS

Exposure to cephalosporins could cause occupational allergic diseases in health care workers (HCWs). We evaluated the prevalence of serum specific IgE and IgG antibodies to cephalosporin-human serum albumin (HSA) conjugate...
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Increased Level of Basophil CD203c Expression Predicts Severe Chronic Urticaria

Ye YM, Yang EM, Yoo HS, Shin YS, Kim SH, Park HS

Increased FcepsilonR1alpha expression with upregulated CD203c expression on peripheral basophils is seen in patients with chronic urticaria (CU). However, there has been no published report on the association between CD203c...
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Serum Specific IgE to Thyroid Peroxidase Activates Basophils in Aspirin Intolerant Urticaria

Shin YS, Suh DH, Yang EM, Ye YM, Park HS

Thyroid antibodies are frequently observed in urticaria patients, but their roles in urticaria are not clearly elucidated. We investigated the role of serum specific IgE to thyroid peroxidase (TPO) in...
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Highlights of human toxocariasis

Magnaval J, Glickman L, Dorchies P, Morassin B

Human toxocariasis is a helminthozoonosis due to the migration of Toxocara species larvae through human organism. Humans become infected by ingesting either embryonated eggs from soil (geophagia, pica), dirty...
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Murine Model of Buckwheat Allergy by Intragastric Sensitization with Fresh Buckwheat Flour Extract

Lee SY, Oh S, Lee K, Jang YJ, Sohn MH, Lee KE, Kim KE

Food allergies affect about 4% of the Korean population, and buckwheat allergy is one of the most severe food allergies in Korea. The purpose of the present study was to...
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Inflammatory and Remodeling Events in Asthma with Chronic Exposure to House Dust Mites: A Murine Model

Ahn JH, Kim CH, Kim YH, Kim SJ, Lee SY, Kim YK, Kim KH, Moon HS, Song JS, Park SH, Kwon SS

Although animal models with ovalbumin have been used to study chronic asthma, there are difficulties in inducing recurrence as well as in maintaining chronic inflammation in this system. Using a...
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Natural Course of Cow's Milk Allergy in Children with Atopic Dermatitis

Suh J, Lee H, Lee JH, Cho J, Yu JS, Kim J, Han Y, Ahn K, Lee SI

Cow's milk is one of the most common food allergens in children with atopic dermatitis (AD). This study was conducted to describe the natural course of cow's milk allergy in...
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Clinical Significance of Serum Interleukin-18 Concentration in the Patients with Atopic Dermatitis

Park DS, Youn YH

BACKGROUND: Interleukin (IL)-18, a potent inducer of interferon gamma (IFN-gamma), is known to have a role in diseases involving type-2 T helper cell responses including atopic dermatitis. In this...
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Studies on the role of interleukin-4 and Fc epsilon RII in the pathogenesis of minimal change nephrotic syndrome

Cho BS, Lee CE, Pyun KH

Childhood minimal change nephrotic syndrome (MCNS) has often been associated with allergic symptoms such as urticaria, bronchial asthma, atopic dermatitis, allergic rhinitis and elevated IgE levels and referred to...
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Downregulation of Orai1 expression in the airway alleviates murine allergic rhinitis

Wang Y, Lin L, Zheng C

Orai1 is the key subunit of the Ca2+-release-activated Ca2+ channel. Our previous report has demonstrated that Orai1 expression in the airway was upregulated in the ovalbumin (OVA)-induced allergic rhinitis (AR)...
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Therapeutic effects of recombinant Salmonella typhimurium harboring CCL22 miRNA on atopic dermatitis-like skin in mice

Yoon WS, Lee SS, Chae YS, Park YK

Th-2-biased immune responses are known to play a key role in the pathogenesis of atopic dermatitis. In particular, the macrophage-derived chemokine CCL22 is directly implicated in Th-2-associated skin inflammatory reactions,...
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Four cases of gastric submucosal mass suspected as anisakiasis

Kim SG, Jo YJ, Park YS, Kim SH, Song MH, Lee HH, Kim JS, Ryou JW, Joo JE, Kim DH

Anisakiasis is a parasitic disease caused by ingestion of raw fish infected with anisakid larvae. Endoscopic changing patterns of submucosal lesions in chronic gastric anisakiasis have not been known yet....
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Cross-Reactivity between Oak and Birch Pollens in Korean Tree Pollinosis

Jeong KY, Son M, Park JH, Park KH, Park HJ, Lee JH, Hong CS, Park JW

Oak and birch trees belong to Fagales order. Specific IgE to pollen allergens of both trees are frequently found in Korea pollinosis patients. Oak trees which comprise 40% of forest...
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