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Waning Effectiveness of One-dose Universal Varicella Vaccination in Korea, 2011–2018: a Propensity Score Matched National Population Cohort

Hong K, Sohn S, Choe YJ, Rhie K, Lee JK, Han MS, Chun BC, Choi EH

Background: Despite high coverage (~98%) of universal varicella vaccination (UVV) in the Republic of Korea since 2005, reduction in the incidence rate of varicella is not obvious. The study aimed to...
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Profiling of T Cell Receptor β-Chain Complimentary Determining Regions 3 Repertoire in Subarachnoid Hemorrhage Patients Using High-Throughput Sequencing

Kim BJ, Ahn JH, Youn DH, Jeon JP

Objective : The adaptive immune response following subarachnoid hemorrhage (SAH) is not well understood. We evaluated and compared the T cell receptor (TCR) immune repertoire of good-grade and poor-grade SAH...
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Neutralizing Antibody Responses to SARS-CoV-2 in Korean Patients Who Have Recovered from COVID-19

Kim YJ, Bae JY, Bae S, Hwang S, Kwon KT, Chang HH, Lee WK, Cui C, Lee GE, Kim SW, Park MS

Purpose: Neutralizing antibodies (NAbs) have been considered effective in preventing and treating viral infections. However, until now, the duration and clinical implications of antibody-mediated nature immunity in Koreans have remained...
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Varicella zoster virus (VZV)-specific immunity and subclinical VZV reactivation in patients with autoimmune diseases

Lee KH, Choi S, Kwon JS, Kim SH, Park SY

Background/Aims: The risk of herpes zoster (HZ) is increased in patients with autoimmune diseases (AID), probably due to immunosuppressive therapy. Methods: This prospective cross-sectional study investigated varicella zoster virus (VZV)-specific immunity...
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Assessing the risk of recurrence of porcine epidemic diarrhea virus in affected farms on Jeju Island, South Korea

Jang G, Lee S, Lee C

Background: Porcine epidemic diarrhea virus (PEDV) is a swine enteropathogenic coronavirus that has devastated the swine industry in South Korea over the last 30 years. The lack of an effective...
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Toll-like Receptor 2 in Autoimmune Inflammation

Marks KE, Cho K, Stickling C, Reynolds JM

TLR signaling is critical for broad scale immune recognition of pathogens and/or danger molecules. TLRs are particularly important for the activation and the maturation of cells comprising the innate immune...
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Herpes Zoster in Breast Cancer Patients: A 15-Year Experience from a Single Tertiary Referral Center in Korea

Song S, Lim JW, Baek J, Roh JY, Park HK, Kim HJ

  • KMID: 2516141
  • Korean J Dermatol.
  • 2021 May;59(4):284-289.
Background: Breast cancer is the second most common cancer and the most common cause of cancer deaths in Korean women. Although tumor-induced mediators and cancer therapy can suppress cell-mediated immunity,...
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Immunosuppression and Neuroinflammation in Stroke Pathobiology

Jiang Q, Stone CR, Elkin K, Geng X, Ding Y

  • KMID: 2515810
  • Exp Neurobiol.
  • 2021 Apr;30(2):101-112.
  • doi: 10.5607/en20033
Over the preceding decades, there have been substantial advances in our knowledge of the pathophysiology of stroke. One such advance has been an increased understanding of the multifarious crosstalk in...
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Effect of pregabalin on nociceptive thresholds and immune responses in a mouse model of incisional pain

Park JH, Cho SH, Kim R, Na SH, Kang Es, Yeom My, Jang Y

Background: It is known that some analgesics as well as pain can affect the immune system. The aim of this study was to investigate the analgesic effect and immunomodulation of...
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Effects of Lactobacillus acidophilus HY7032 and Lactobacillus reuteri HY7506 isolated from dog feces on welfare and hair in companion dogs

Lee HJ, Lee SW

Precise combinations of probiotics can be useful in dog nutrition, treatment and care. Also, host specificity must be considered in order to increase the effectiveness of probiotics. In this study,...
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Nutrition agenda during the era of the COVID-19 pandemic

Lee M

This review describes the risk factors of the nutrition crisis in coronavirus disease 2019 (COVID-19) infections and suggests precision nutrition against long-term psychological and physiological stress. The mandatory quarantine and...
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Understanding the Host Innate Immune Responses against SARS-CoV-2 Infection and COVID-19 Pathogenesis

Kang YW, Park S, Lee KJ, Moon D, Kim YM, Lee SW

The emergence of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has become a significant health concern worldwide. Undoubtedly, a better understanding of the innate and adaptive immune...
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What We Do Know and Do Not Yet Know about COVID-19 Vaccines as of the Beginning of the Year 2021

Yoo JH

Coronavirus disease 2019 (COVID-19), which started at the end of 2019 and has spread worldwide, has remained unabated in 2021. Since non-pharmaceutical interventions including social distancing are facing limitations in...
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Immune responses against autologous tumor and human papilloma virus in lymph nodes from patients with penile cancer

Zhang L, Zirakzadeh AA, Rosvall J, Hedlund M, Hu PS, Riklund K, Sherif A, Winqvist O

Purpose: Nearly half of penile cancers are related to human papillomavirus (HPV) infection. Investigations of tumor- and HPVspecific T cell reactivity in regional lymph nodes (LNs) from patients with penile...
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Nlrp3, Csf3, and Edn1 in Macrophage Response to Saturated Fatty Acids and Modified Low-Density Lipoprotein

Youk H, Kim M, Lee CJ, Oh J, Park S, Kang SM, Kim JH, Ann Sj, Lee SH

Background and Objectives: The relationship between metabolic stress, inflammation, and cardiovascular disease is being studied steadily. The aim of this study was to evaluate the effect of palmitate (PA) and...
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COVID-19 herd immunity in the absence of a vaccine: an irresponsible approach

Khalife J, VanGennep D

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread rapidly throughout the human population, the concept of “herd immunity” has attracted the attention of both decision-makers and the...
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The changes of immune-related molecules within the ileal mucosa of piglets infected with porcine circovirus type 2

Shi F, Li Q, Zou Z, Wang Y, Hou X, Zhang Y, Song Q, Zhou S, Li H

Background: Enteritis is one of the most frequently reported symptoms in piglets infected with porcine circovirus type 2 (PCV2), but the immunopathogenesis has not been reported. Objectives: This study examined the...
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Vitamin D and COVID-19: Is something better than nothing?

Lewiecki EM

There is no abstract.
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Very Early-Onset Inflammatory Bowel Disease: A Challenging Field for Pediatric Gastroenterologists

Arai K

With the increasing number of children with inflammatory bowel disease (IBD), very earlyonset IBD (VEO-IBD), defined as IBD that is diagnosed or that develops before 6 years of age, has...
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Immune Activation and Deficit in Neurotransmitters Synthesis in Treatment Resistant Depression: About a Case of Hashimoto Encephalopathy

Ellul P, Gasnier M, Trebossen V, Gaillard R

We report a case of Hashimoto encephalopathy initially presented as a drug-resistant depression with predominant apathy and asthenia, successfully treated with cyclophosphamide. We suspected that the psychiatric symptoms were due...
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