- The Immunosuppressive Potential of Cholesterol Sulfate Through T Cell Microvilli Disruption
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Park JS, Chung IJ, Kim HR, Jun CD
- KMID: 2544692
- Immune Netw.
- 2023 Jun;23(3):e29.
- doi: 10.4110/in.2023.23.e29
Cholesterol (CL) is required for various biomolecular production processes, including those of cell membrane components. Therefore, to meet these needs, CL is converted into various derivatives. Among these derivatives is... -
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- Extracellular Acidification Augments NLRP3-Mediated Inflammasome Signaling in Macrophages
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Chae BJ, Lee KS, Hwang I, Yu JW
- KMID: 2544687
- Immune Netw.
- 2023 Jun;23(3):e23.
- doi: 10.4110/in.2023.23.e23
Inflammation is a series of host defense processes in response to microbial infection and tissue injury. Inflammatory processes frequently cause extracellular acidification in the inflamed region through increased glycolysis and... -
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- NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain
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Byun DJ, Lee J, Yu JW, Hyun YM
- KMID: 2544691
- Immune Netw.
- 2023 Jun;23(3):e27.
- doi: 10.4110/in.2023.23.e27
Neutrophil extracellular traps (NETs) exert a novel function of trapping pathogens. Released NETs can accumulate in inflamed tissues, be recognized by other immune cells for clearance, and lead to tissue... -
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- Altered Frequency, Activation, and Clinical Relevance of Circulating Innate and Innate-Like Lymphocytes in Patients With Alcoholic Liver Cirrhosis
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Park KJ, Jin HM, Cho YN, Yoon JH, Kee SJ, Kim HS, Park YW
- KMID: 2544686
- Immune Netw.
- 2023 Jun;23(3):e22.
- doi: 10.4110/in.2023.23.e22
Alcoholic liver cirrhosis (ALC) is caused by chronic alcohol overconsumption and might be linked to dysregulated immune responses in the gut-liver axis. However, there is a lack of comprehensive research... -
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- CD103+ Cells and Chemokine Receptor Expression in Breast Cancer
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Seo EH, Song GY, Oh CS, Kim SH, Kim WS, Lee SH
- KMID: 2544689
- Immune Netw.
- 2023 Jun;23(3):e25.
- doi: 10.4110/in.2023.23.e25
Mucosal environments harbour lymphocytes, which express several adhesion molecules, including intestinal homing receptors and integrin αE/β7 (CD103). CD103 binds E-cadherin, an integrin receptor expressed in intestinal endothelial cells. Its expression... -
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- SARS-CoV-2 Infection Induces HMGB1 Secretion Through Post-Translational Modification and PANoptosis
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Kwak MS, Choi S, Kim J, Lee H, Park IH, Oh J, Mai DN, Cho NH, Nam KT, Shin JS
- KMID: 2544690
- Immune Netw.
- 2023 Jun;23(3):e26.
- doi: 10.4110/in.2023.23.e26
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces excessive pro-inflammatory cytokine release and cell death, leading to organ damage and mortality. High-mobility group box 1 (HMGB1) is one of the... -
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- Distinct Transcriptional and Functional Differences of Lung Resident and Monocyte-Derived Alveolar Macrophages During the Recovery Period of Acute Lung Injury
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Hou F, Wang H, Zheng K, Yang W, Xiao K, Rong Z, Xiao J, Li J, Cheng B, Tang L, Xie L
- KMID: 2544688
- Immune Netw.
- 2023 Jun;23(3):e24.
- doi: 10.4110/in.2023.23.e24
In acute lung injury, two subsets of lung macrophages exist in the alveoli: tissue-resident alveolar macrophages (AMs) and monocyte-derived alveolar macrophages (MDMs). However, it is unclear whether these 2 subsets of... -
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