- IL-17 Imbalance Promotes the Pyroptosis in Immune-Mediated L
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Xu W, Wang Y, Jin C, Zhang W, Chen J, Chen X, Gao J, Gao J, Wang H
- KMID: 2549966
- Immune Netw.
- 2023 Dec;23(6):e46.
- doi: 10.4110/in.2023.23.e46
Autoimmune hepatitis (AIH) affects all age group and occurs mainly in women. Pyroptosis is a novel programmed cell death featured with cell bursting and release of proinflammatory cytokines. A deeper... -
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- Comparing the Benefits and Drawbacks of Stem Cell Therapy Based on the Cell Origin or Manipulation Process: Addressing Immunogenicity
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Chang SH, Park CG
- KMID: 2549964
- Immune Netw.
- 2023 Dec;23(6):e44.
- doi: 10.4110/in.2023.23.e44
Mesenchymal stem cells (MSCs) are effective in treating autoimmune diseases and managing various conditions, such as engraftment of allogeneic islets. Additionally, autologous and HLA-matched allogeneic MSCs can aid in the... -
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- Low Neutralizing Activities to the Omicron Subvariants BN.1 and XBB.1.5 of Sera From the Individuals Vaccinated With a BA.4/5-Containing Bivalent mRNA Vaccine
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Nham E, Kim J, Lee J, Park H, Kim J, Lee S, Choi J, Kim KT, Yoon JG, Hwang SYH, Song JY, Cheong HJ, Kim WJ, Park MS, Noh JY
- KMID: 2549963
- Immune Netw.
- 2023 Dec;23(6):e43.
- doi: 10.4110/in.2023.23.e43
The continuous emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) variants has provided insights for updating current coronavirus disease 2019 (COVID-19) vaccines. We examined the neutralizing activity of Abs induced... -
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- Intranasal Immunization With Nanoparticles Containing an Orientia tsutsugamushi Protein Vaccine Candidate and a Polysorbitol Transporter Adjuvant E
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Kim CG, Kim WK, Kim N, Pyung YJ, Park DJ, Lee JC, Cho CS, Chu H, Yun CH
- KMID: 2549967
- Immune Netw.
- 2023 Dec;23(6):e47.
- doi: 10.4110/in.2023.23.e47
Scrub typhus, a mite-borne infectious disease, is caused by Orientia tsutsugamushi. Despite many attempts to develop a protective strategy, an effective preventive vaccine has not been developed. The identification of... -
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- Promising Therapeutic Effects of Embryonic Stem Cells-Origin Mesenchymal Stem Cells in Experimental Pulmonary Fibrosis Models: Immunomodulatory and Anti-Apoptotic Mechanisms
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Lee H, Jeong OY, Park HJ, Lee SL, Bok Ey, Kim M, Suh YS, Cheon YH, Kim HO, Kim S, Chun SH, Park JM, Lee YJ, Lee SI
- KMID: 2549965
- Immune Netw.
- 2023 Dec;23(6):e45.
- doi: 10.4110/in.2023.23.e45
Interstitial lung disease (ILD) involves persistent inflammation and fibrosis, leading to respiratory failure and even death. Adult tissue-derived mesenchymal stem cells (MSCs) show potential in ILD therapeutics but obtaining an... -
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- Recombinant Human Bone Morphogenetic Protein-2 Priming of Mesenchymal Stem Cells Ameliorate Acute Lung Injury by Inducing Regulatory T Cells
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Lee J, Jang J, Cha SR, Lee SB, Hong SH, Bae HS, Lee YJ, Yang SR
- KMID: 2549968
- Immune Netw.
- 2023 Dec;23(6):e48.
- doi: 10.4110/in.2023.23.e48
Mesenchymal stromal/stem cells (MSCs) possess immunoregulatory properties and their regulatory functions represent a potential therapy for acute lung injury (ALI). However, uncertainties remain with respect to defining MSCs-derived immunomodulatory pathways. Therefore,... -
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