- As a Modulator, Multitasking Roles of SIRT1 in Respiratory Diseases
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Zhou Y, Zhang F, Ding J
- KMID: 2536248
- Immune Netw.
- 2022 Jun;22(3):e21.
- doi: 10.4110/in.2022.22.e21
As far the current severe coronavirus disease 2019 (COVID-19), respiratory disease is still the biggest threat to human health. In addition, infectious respiratory diseases are particularly prominent. In addition to... -
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- Evaluation of ImmunoproteasomeSpecific Proteolytic Activity Using Fluorogenic Peptide Substrates
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Kim S, Park SH, Choi WH, Lee MJ
- KMID: 2536255
- Immune Netw.
- 2022 Jun;22(3):e28.
- doi: 10.4110/in.2022.22.e28
The 26S proteasome irreversibly hydrolyzes polyubiquitylated substrates to maintain protein homeostasis; it also regulates immune responses by generating antigenic peptides. An alternative form of the 26S proteasome is the immunoproteasome,... -
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- Amelioration of DSS-Induced Acute Colitis in Mice by Recombinant Monomeric Human Interleukin-22
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Kim S, Hong EH, Lee CK, Ryu Y, Jeong H, Heo S, Lee JJ, Ko HJ
- KMID: 2536253
- Immune Netw.
- 2022 Jun;22(3):e26.
- doi: 10.4110/in.2022.22.e26
IL-22, a pleiotropic cytokine, is known to have a profound effect on the regeneration of damaged intestinal barriers. The tissue-protective properties of IL-22 are expected to be potentially exploited in... -
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- Antibody Response Induced by Two Doses of ChAdOx1 nCoV-19, mRNA-1273, or BNT162b2 in Liver Transplant Recipients
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Lim SY, Yoon YI, Kim JY, Tak E, Song GW, Kim SH, Lee SG
- KMID: 2536251
- Immune Netw.
- 2022 Jun;22(3):e24.
- doi: 10.4110/in.2022.22.e24
Coronavirus disease 2019 (COVID-19) vaccination in immunocompromised, especially transplant recipients, may induce a weaker immune response. But there are limited data on the immune response after COVID-19 vaccination in liver... -
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- Integration and Reanalysis of Four RNA-Seq Datasets Including BALF, Nasopharyngeal Swabs, Lung Biopsy, and Mouse Models Reveals Common Immune Features of COVID-19
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Alberts R, Chan SC, Meng QF, He S, Rao L, Liu X, Zhang Y
- KMID: 2536249
- Immune Netw.
- 2022 Jun;22(3):e22.
- doi: 10.4110/in.2022.22.e22
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndromecoronavirus-2 (SARS-CoV-2), has spread over the world causing a pandemic which is still ongoing since its emergence in late 2019. A... -
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- Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria or Pseudomonas aeruginosa Infection
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Schenkel AR, Mitchell JD, Cool CD, Bai X, Groshong S, Koelsch T, Verma D, Ordway D, Chan ED
- KMID: 2536254
- Immune Netw.
- 2022 Jun;22(3):e27.
- doi: 10.4110/in.2022.22.e27
Little is known of the lung cellular immunophenotypes in patients with non-tuberculous mycobacterial lung disease (NTM-LD). Flow-cytometric analyses for the major myeloid and lymphoid cell subsets were performed in less-... -
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- IL-34 Aggravates Steroid-Induced Osteonecrosis of the Femoral Head via Promoting Osteoclast Differentiation
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Wang F, Min HS, Shan H, Yin F, Jiang C, Zong Y, Ma X, Lin Y, Zhou Z, Yu X
- KMID: 2536252
- Immune Netw.
- 2022 Jun;22(3):e25.
- doi: 10.4110/in.2022.22.e25
IL-34 can promote osteoclast differentiation and activation, which may contribute to steroidinduced osteonecrosis of the femoral head (ONFH). Animal model was constructed in both BALB/c and IL-34 deficient mice to... -
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- Modeling Incorporating the SeverityReducing Long-term Immunity: Higher Viral Transmission Paradoxically Reduces Severe COVID-19 During Endemic Transition
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Hong H, Noh JY, Lee H, Choi S, Choi B, Kim JK, Shin EC
- KMID: 2536250
- Immune Netw.
- 2022 Jun;22(3):e23.
- doi: 10.4110/in.2022.22.e23
Natural infection with severe acute respiratory syndrome-coronavirus-2 or vaccination induces virus-specific immunity protecting hosts from infection and severe disease. While the infection-preventing immunity gradually declines, the severity-reducing immunity is relatively... -
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