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Improvement of Re-examination System of New Drugs: A Safety Monitoring Study using Real-World Data on Re-examined Drugs

Kim MS, Jeong NY, Kim Y, Choi NK

Objective: Although the re-examination of the safety profiles of approved drugs including the Drug Use-Results Survey (DURS) is conducted in Korea, the evaluation process is limited due to insufficient data...
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Effectiveness of monthly intravenous ibandronate injections in a real-world setting: Subgroup analysis of a postmarketing observational study

Takeuchi Y, Hashimoto , Kakihata H, Nishida Y, Kumagai M, Yamagiwa C

OBJECTIVES: The favorable safety and consistent effectiveness of monthly intravenous (IV) ibandronate injections was demonstrated in a prospective, postmarketing, observational study in Japanese patients with osteoporosis. Here, we present subgroup...
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Efficacy, safety, and compliance of ibandronate treatment for 3 years in postmenopausal Japanese women with primary osteoporosis

Suzuki T, Nakamura Y, Kato H

OBJECTIVES: The aim of this study was to examine the efficacy, safety, and adherence of ibandronate (IBN) treatment with or without vitamin D supplementation for 3 years in Japanese women...
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Safety and effectiveness of monthly intravenous ibandronate injections in a prospective, postmarketing, and observational study in Japanese patients with osteoporosis

Takeuchi Y, Hashimoto , Nishida Y, Yamagiwa C, Tamura T, Atsumi A

OBJECTIVES: This postmarketing, observational study evaluated the safety and effectiveness of monthly intravenous (IV) ibandronate in Japanese patients with osteoporosis. METHODS: Eligible patients received monthly IV ibandronate 1mg for 12 months....
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Retrospective study for the change of bone density over 2 years in patients at Sorokdo hospital

Park SK

INTRODUCTION: Author investigated the baseline of BMD and T-score through analysis of bone density for 254 ex-hansen patients in 2014. This study aims to evaluate the change of BMD and...
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Comparison of effectiveness and safety of ibandronate and minodronate combined with eldecalcitol in primary osteoporosis of women: A 1-year follow-up study

Tanaka M, Nakamura Y, Itoh S, Kato Y

OBJECTIVES: This is an open labeled and retrospective cohort study which compared the effectiveness and safety of ibandronate (IBN) and minodronate (MIN) combined with eldecalcitol (ELD) in primary osteoporosis of...
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Efficacy of a Once-Monthly Pill Containing Ibandronate and Cholecalciferol on the Levels of 25-Hydroxyvitamin D and Bone Markers in Postmenopausal Women with Osteoporosis

Cho IJ, Chung HY, Kim SW, Lee JW, Lee TW, Kim HS, Kim SG, Choi HS, Choi SH, Shin CS, Oh KW, Min YK, Koh JM, Rhee Y, Byun DW, Chung YS, Park JH, Chung DJ, Shong M, Hong EG, Lee CB, Baek KH, Kang MI

BACKGROUND: The present study evaluated the efficacy of a combination of ibandronate and cholecalciferol on the restoration of the levels of 25-hydroxyvitamin D (25[OH]D) and various bone markers in postmenopausal...
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Evaluation of Osseointegration around Tibial Implants in Rats by Ibandronate-Treated Nanotubular Ti-32Nb-5Zr Alloy

Nepal M, Li L, Bae TS, Kim BI, Soh Y

Materials with differing surfaces have been developed for clinical implant therapy in dentistry and orthopedics. This study was designed to evaluate bone response to titanium alloy containing Ti-32Nb-5Zr with nanostructure,...
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Effect of Ibandronate and hPTH on the Viscoelastic Response of Ovariectomized Rat Femur

Yang X, Muthukumaran P, Lee T

  • KMID: 2010315
  • Osteoporosis.
  • 2011 Dec;9(3):222-230.
PTH and ibandronate are proven to be effective in reversing negative effects of postmenopausal osteoporosis in terms of bone architecture and density. However, the changes of viscoelastic properties of the...
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Morphological and Mechanical Changes in Ovariectomized Rat Tibia with Treatments of Ibandronate and Parathyroid Hormone

Yang X, Chan YH, Muthukumaran P, Lee T

  • KMID: 2314079
  • Osteoporosis.
  • 2010 Dec;8(3):255-265.
Osteoporosis is a debilitating disease affecting the elderly population, associated with compromised stability and reduced mobility of the bone. Osteoporosis is diagnosed as a condition when the measured bone mineral...
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