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Mizoribine-mediated Apoptosis Signaling in Jurkat T Cells

Seo KW, Chung SH, Chung SY, Kim SK, Choi SN

  • KMID: 1896293
  • J Korean Surg Soc.
  • 2004 Apr;66(4):259-270.
PURPOSE: Mizoribine (MZR), an inhibitor of Inosine monophosphate (IMP) dehydrogenase which depletes cellular GTP, is clinically used as an immunosuppressive drug. This study was designed to evaluate the mechanism by...
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