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Clinical Characteristics Associated with Electrocardiographic Left Ventricular Hypertrophy in Clinical Normotensives without a History of Hypertension: a Cross-Sectional Study

Lee H, Song HJ, Paek YJ, Park KH, Noh HM, Kim G, Seo YG

BACKGROUND: This study evaluated factors independently associated with electrocardiographic left ventricular hypertrophy (ECG-LVH) in subjects who were normotensive on clinical measurement and had no prior history of hypertension. METHODS: This cross-sectional...
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Prevalence of Fabry Disease in Korean Men with Left Ventricular Hypertrophy

Kim WS, Kim HS, Shin J, Park JC, Yoo HW, Takenaka T, Tei C

BACKGROUND: Fabry disease is an X-linked recessive disorder caused by deficiency of the lysosomal enzyme α-galactosidase A (α-Gal A). Previous studies identified many cases of Fabry disease among men with...
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Cardiac Structural or Functional Changes Associated with CHAâ‚‚DSâ‚‚-VASc Scores in Nonvalvular Atrial Fibrillation: A Cross-Sectional Study Using Echocardiography

Jang AY, Yu J, Park YM, Shin MS, Chung WJ, Moon J

BACKGROUND: CHA2DS2-VASc is the most widely accepted scoring system for atrial fibrillation (AF) to assess stroke risk, although little has been revealed regarding the accompanying cardiac functional/structural changes. This echocardiography...
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Clinical usefulness of bioimpedance analysis for assessing volume status in patients receiving maintenance dialysis

Park JH, Jo YI, Lee JH

Chronic volume overload is associated with left ventricular hypertrophy and high cardiovascular mortality in patients undergoing dialysis. Therefore, estimating body fluid status is important in these patients. However, most dry-weight...
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A novel GLA mutation in a Korean boy with an early cardiac manifestation of Fabry disease

Kwon S, Park JS, Jung JH, Hwang SK, Kim YH, Lee YJ

Fabry disease (FD) is a rare X-linked lysosomal storage disorder caused by the deficiency of α-galactosidase A. Patients with classical FD present acroparesthesia, hypohidrosis, cornea verticillata, disseminated angiokeratoma, and microalbuminuria...
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Apoptosis and remodeling in adriamycin-induced cardiomyopathy rat model

Hong YM, Lee H, Cho MS, Kim KC

PURPOSE: The mechanism for the pathogenesis of adriamycin (ADR)-induced cardiomyopathy is not yet known. Different hypotheses include the production of free radicals, an interaction between ADR and nuclear components, and...
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Prognostic Application of Thoracic Aortic Calcium Scoring for Adverse Clinical Outcome Risk in Elderly Patients with Left Ventricular Hypertrophy

Cho IJ, Chang HJ, Lee SE, Shim CY, Hong GR, Chung N

BACKGROUND AND OBJECTIVES: Left ventricular hypertrophy (LVH) is associated with poor cardiovascular outcomes. Heavy aortic calcification exacerbates arterial stiffness, which consequently heightens left ventricular (LV) afterload. We assessed the usefulness...
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Impact of Gender on the Association between Low Serum Prolactin and Left Ventricular Mass in Subjects with Prediabetes

El-Eshmawy MM, Elkhamisy , Elsayed E, Kamal S

BACKGROUND: Low circulating prolactin hormone was associated with increased risk for type 2 diabetes mellitus. An inverse association of serum prolactin with cardiac remodeling was also previously suggested. Thus, the...
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ST segment

Kwak CH

The ST segment corresponds to the plateau phase of ventricular repolarization, i.e., phase 2 of the action potential. Heightened awareness of the characteristic patterns of ST segment changes is vital...
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Effects of a Proteasome Inhibitor on Cardiomyocytes in a Pressure-Overload Hypertrophy Rat Model: An Animal Study

Kim IS, Jo WM

BACKGROUND: The ubiquitin-proteasome system (UPS) is an important pathway of proteolysis in pathologic hypertrophic cardiomyocytes. We hypothesize that MG132, a proteasome inhibitor, might prevent hypertrophic cardiomyopathy (CMP) by blocking the...
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Carotid Atherosclerosis and Electrocardiographic Left Ventricular Hypertrophy in the General Population: The Namwon Study

Kim NH, Shin MH, Kweon SS, Ko JS, Lee YH

This study aimed to investigate the relationship between carotid atherosclerosis and left ventricular hypertrophy on electrocardiogram (ECG-LVH) on adults living in the community. A total of 9,266 adults who participated...
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Identification of a Novel GLA Mutation (L206 P) in a Patient with Fabry Disease

Kim JH, Kim GH, Park HS, Choi JA, Bae JM, Cho U

We report a new α-Galactosidase A (αGal-A) mutation in a 39-year-old Korean born, male Fabry disease patient. Fabry disease is a devastating, progressive inborn error of metabolism caused by X-linked...
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Association Between Interleukin-18 Level and Left Ventricular Mass Index in Hypertensive Patients

ÖZzbïçer S, Uluçam ZM

BACKGROUND AND OBJECTIVES: In clinical trials, hypertensive patients tend to have higher interleukin-18 (IL-18) concentrations than normotensive groups, but the relationship between IL-18 and left ventricular hypertrophy (LVH), which is...
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Perioperative management of left ventricular diastolic dysfunction and heart failure: an anesthesiologist's perspective

Ryu T, Song SY

Anesthesiologists frequently see asymptomatic patients with diastolic dysfunction or heart failure for various surgeries. These patients typically show normal systolic function but abnormal diastolic parameters in their preoperative echocardiographic evaluations....
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A multicenter cohort study of primary hypertension in Korea: study design and interim analysis of the Korean registry of target organ damage in hypertension (KorHR)

Choi SW, Han SW, Ok JS, Yoo BS, Shin MS, Park SH, Ryu KH

BACKGROUND: The Korean Registry of Target Organ Damage in Hypertension aims to evaluate the clinical characteristics and prevalence of subclinical target organ damage in Korean hypertensive patients. METHOD: This is a...
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Attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular disease in the general practice: results of the Italian hypertension and brain survey

Tocci G, Cicero AF, Salvetti M, Musumeci M, Ferrucci A, Borghi C, Volpe M

BACKGROUND: The aim of this survey was to evaluate attitudes and preferences for the clinical management of hypertension and hypertension-related cerebrovascular diseases (CVD) in Italy. METHODS: A predefined 16-item survey questionnaire...
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Revised definition of predicted left ventricular mass using ambulatory blood pressure in healthy Korean adults

Kim BK, Xu E, Choi BY, Lee Y, Kim SG, Yamori Y, Shin J

BACKGROUND: Left ventricular hypertrophy is influenced by both hemodynamic and non-hemodynamic factors. Ambulatory blood pressure is correlated with left ventricular hypertrophy. We established the influences of hemodynamic and non-hemodynamic factors,...
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Multimodality Imaging for Left Ventricular Hypertrophy Severity Grading: A Methodological Review

Alkema M, Spitzer E, Soliman OI, Loewe C

Left ventricular hypertrophy (LVH), defined by an increase in left ventricular mass (LVM), is a common cardiac finding generally caused by an increase in pressure or volume load. Assessing severity...
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Soluble ST2 Levels and Left Ventricular Structure and Function in Patients With Metabolic Syndrome

Celic V, Majstorovic A, Pencic-Popovic B, Sljivic A, Lopez-Andres N, Roy I, Escribano , Beunza M, Melero A, Floridi F, Magrini L, Marino R, Salerno G, Cardelli P, Di Somma S

BACKGROUND: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family. Considering that metabolic syndrome (MetS) is...
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Idiopathic midaortic syndrome with malignant hypertension in 3-year-old boy

Ahn KJ, Yoon JK, Kim GB, Kwon BS, Bae EJ, Noh CI

Midaortic syndrome (MAS) is a rare vascular disease that commonly causes renovascular hypertension. The lumen of the abdominal aorta narrows and the ostia of the branches show stenosis. MAS is...
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