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The Effect of Blood Lipids, Type 2 Diabetes, and Body Mass Index on Parkinson’s Disease: A Korean Mendelian Randomization Study

Park KW, Hwang YS, Lee SH, Jo S, Chung SJ

Objective Associations between various metabolic conditions and Parkinson’s disease (PD) have been previously identified in epidemiological studies. We aimed to investigate the causal effect of lipid levels, type 2 diabetes...
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Age at first childbirth and the risk of hypertriglyceridemia among Korean women

Choi HR, Kim HC

OBJECTIVES: We aimed to investigate the association of age at first childbirth with the risk of hypertriglyceridemia among Korean women. METHODS: This study used data from the Korean Genome and Epidemiology...
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Association between Serum Folic Acid Level and the Risk of Hypertriglyceridemia in Korean Female: Analysis Based on 2016–2018 Korea National Health and Nutrition Examination Survey

Lee JY, Lee DC, Yoo NY, Lee HJ

Background: Serum folic acid is associated with atherosclerosis and dyslipidemia. However, the association between folic acid and triglycerides is controversial. Therefore, we aimed to analyze the association between serum folic...
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Differences in Clinical Features between Hypertriglyceridemia-Induced Acute Pancreatitis and Other Etiologies of Acute Pancreatitis

Kim TI, Jeong HT, Song JE, Kim HG, Han J

Background/Aim: The aim of this study was to compare clinical features of hypertriglyceridemia-induced acute pancreatitis (HTGAP) with those of biliary acute pancreatitis (BAP) and alcoholic acute pancreatitis (AAP), respectively. Methods: Medical...
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Hypertriglyceridemia with acute pancreatitis in a 14-year-old girl with diabetic ketoacidosis

Park H, Kim MS, Kim J, Lee SM, Cho SY, Yoo EG, Jin DK

Diabetic ketoacidosis (DKA) is a medically fatal condition in poorly controlled hyperglycemia or newly diagnosed diabetes mellitus. Severe hypertriglyceridemia (HTG) is an uncommon complication of DKA and can be associated...
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Hypertriglyceridemia: A Neglected Risk Factor for Ischemic Stroke?

Liang Hj, Zhang Qy, Hu Yt, Liu Gq, Qi R

Hypertriglyceridemia is caused by defects in triglyceride metabolism and generally manifests as abnormally high plasma triglyceride levels. Although the role of hypertriglyceridemia may not draw as much attention as that...
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Hypertriglyceridemia is a Risk Factor for Fever in Early Acute Non-biliary Pancreatitis

Lee SH, Park JM, Kim JH, Kim TS, Kang CD

Background/Aims: Fever is a common symptom of acute pancreatitis (AP). This study examined the factors associated with fever due to pancreatic inflammation in the early stages of non-biliary AP. Methods: This...
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Genotype - phenotype correlation in an adolescent girl with pathogenic PPARy genetic variation that caused severe hypertriglyceridemia and early onset type 2 diabetes

Gutierrez Alvarez A, Yachelevich N, Kohn B, Brar PC

Severe hypertriglyceridemia (HTG) (>885 mg/dL) can be caused by familial partial lipodystrophy type 3 (FPLD3), an autosomal dominant disorder caused by loss of function of the peroxisome proliferator-activated receptor gamma...
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Role of Genetics in Preventive Cardiology: Focused on Dyslipidemia

Lee SH

Dyslipidemia is a strong risk factor for cardiovascular disease as well as a major target for its prevention. Along with the progress in genetic research techniques and bioinformatics analysis, genetic...
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Effector Memory CD8 + and CD4 + T Cell Immunity Associated with Metabolic Syndrome in Obese Children

Yang DH, Lee H, Lee N, Shin MS, Kang I, Kang KS

Purpose: We investigated the association of effector memory (EM) CD8 + T cell and CD4 + T cell immunity with metabolic syndrome (MS). Methods: Surface and intracellular staining of peripheral blood...
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Concurrent Diabetic Ketoacidosis and Acute Pancreatitis in Mild Hypertriglyceridemia: An Enigmatic Triangle

Cho E, Park CH

Hypertriglyceridemia (HTG) is a well-established cause of acute pancreatitis (AP). Diabetic ketoacidosis (DKA) leads to lipolysis and HTG, and can result in AP. Triad of AP, DKA, and HTG is...
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Stressful life events and serum triglyceride levels: the Cardiovascular and Metabolic Diseases Etiology Research Center cohort in Korea

Anni NS, Jung SJ, Shim JS, Jeon YW, Lee GB, Kim HC

OBJECTIVES: Elevated serum triglyceride levels are a risk factor for developing cardiovascular disease. A number of studies have demonstrated a positive association between psychological stress and serum triglyceride levels. However,...
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Clinical Approach for Patients with Hypertriglyceridemia-Induced Acute Pancreatitis

Kim SH, Son BK

Hypertriglyceridemia is an important cause of acute pancreatitis, and its symptoms are similar to those of pancreatitis of other causes. Moreover, the possibility of recurrence renders accurate diagnosis critical, and...
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Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice

Mishra AP, Siva AB, Gurunathan C, Komala Y, Lakshmi BJ

WDR13 - a WD repeat protein, is abundant in pancreas, liver, ovary and testis. Absence of this protein in mice has been seen to be associated with pancreatic β-cell proliferation,...
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Evaluation of the clinical accuracy of six portable blood glucose meters in dogs

Shin MK, Kim H, Yun T, Kang JH, Kang BT

Abstract: Portable blood glucose meters (PBGMs) are widely used because of their practicality. However, the accuracy of PBGMs has frequently been questioned. The objectives of this study were to evaluate...
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Association between dairy product intake and hypertriglyceridemia in Korean adults

Park SJ, Park J, Song HJ, Lee CH, Lee HJ

BACKGROUND/OBJECTIVES: Hypertriglyceridemia may be a more important predictor of cardiovascular disease in Asian population consuming carbohydrate-rich foods than in Western populations. Dairy products are known to play a beneficial role...
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Efficacy and Safety of Omega-3 Fatty Acids in Patients Treated with Statins for Residual Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Jun JE, Jeong IK, Yu JM, Kim SR, Lee IK, Han KA, Choi SH, Kim SK, Park HK, Mok JO, Lee YH, Kwon HS, Kim SH, Kang HC, Lee SA, Lee CB, Choi KM, Her SH, Shin WY, Shin MS, Ahn HS, Kang SH, Cho JM, Jo SH, Cha TJ, Kim SY, Won KH, Kim DB, Lee JH, Lee MK

BACKGROUND: Cardiovascular risk remains increased despite optimal low density lipoprotein cholesterol (LDL-C) level induced by intensive statin therapy. Therefore, recent guidelines recommend non-high density lipoprotein cholesterol (non-HDL-C) as a secondary...
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Efficacy and Safety of Prescription Omega-3 Fatty Acids Added to Stable Statin Therapy in Korean Patients with Type 2 Diabetes and Hypertriglyceridemia: a Randomized Controlled Trial

Son JW, Kim CH, Nam MS, Park IB, Yoo SJ

OBJECTIVE: The aim of this study was to investigate the effects of omega-3 fatty acids added to statin monotherapy in Korean patients with type 2 diabetes who have persistent hypertriglyceridemia...
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Hypertriglyceridemia-induced Severe Necrotizing Pancreatitis Following Low Dose Tamoxifen Administration

Jang YH, Kim HJ

A 51-year-old woman visited the emergency room with severe abdominal pain of acute onset. She had undergone a breast cancer operation one year previously and had been taking a half-dose...
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Acute Pancreatitis in a Pregnant Patient with Type IV Hyperlipoproteinemia

Lee SH, Jun JH, Doh YS, Jang JW, Kim SH, Baek IH, Jung SH

Most cases of hypertriglyceridemia (HTG)-induced gestational pancreatitis occur when a person with hyperlipidemia is overweight due to pregnancy or has secondary triggers associated with triglycerides (TGs). In Korea, 6 cases...
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