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Laparoscopic Splenectomy for a Patient with Splenomegaly and Hypersplenism due to Idiopathic Portal Hypertension

Yang K, Yun SP, Kim JH, Kim DH, Kim HS, Seo HI

Idiopathic portal hypertension (IPH) is a rare disorder which is clinically characterized by portal hypertension, splenomegaly, hypersplenism and the absence of liver cirrhosis. Patients with IPH have massive splenomegaly leading...
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Stem Cells and Niemann Pick Disease

Andolina M

  • KMID: 2054557
  • Int J Stem Cells.
  • 2014 May;7(1):30-32.
BACKGROUND AND OBJECTIVES: Niemann Pick A disease causes a progressive accumulation of sphyngomyelin in several organs and the survival of the patients is usually limited to three years. We describe...
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A Case of Immune Thrombocytopenic Purpura Associated with Scrub Typhus

Kim HA, Lee JY, Hyun M, Ryu SY

Thrombocytopenia is a common manifestation of rickettsial disease. However, the pathogenesis of thrombocytopenia in many rickettsial diseases is poorly understood. Thrombocytopenia may be associated with consumption due to widespread endothelial...
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Tuberculosis of the Spleen as a Cause of Fever of Unknown Origin and Splenomegaly

Pottakkat , Kumar A, Rastogi A, Krishnani , Kapoor VK, Saxena R

  • KMID: 2167211
  • Gut Liver.
  • 2010 Mar;4(1):94-97.
BACKGROUND/AIMS: Splenic involvement of tuberculosis, which is rare, warrants better definition in the current era of resurgence of tuberculosis. METHODS: Out of 339 splenectomies performed between January 1989 and December 2008...
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Hamartoma of the Spleen Diagnosed after Surgical Resection: Three Case Reports

Kim HH, Park EK, Seoung JS, Hur YH, Koh YS, Kim JC, Cho CK, Kim HJ

  • KMID: 2305255
  • Korean J Hepatobiliary Pancreat Surg.
  • 2010 Dec;14(4):273-279.
Hamartoma of the spleen is a rare benign lesion and the pathogenesis of this is not completely understood. It is usually incidentally discovered during an operation or autopsy. Since the...
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A Case of Hemophagocytic Syndrome Induced by Adenovirus Infection after Splenectomy

Park SH, Lee KS

  • KMID: 2168958
  • Clin Pediatr Hematol Oncol.
  • 2009 Apr;16(1):49-53.
Hemophagocytic lymphohistiocytosis (HLH) is a rare but sometimes fatal disease. Its main features are prolonged fever, hepatosplenomegaly, cytopenias, and hemophagocytosis in the bone marrow, lymph nodes and other tissues. Hemophagocytic...
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Recurrent portal and superior mesenteric vein thrombosis in a patient with idiopathic portal hypertension

Rim KN, Sohn JH, Kim HS, Kim TY, Eun CS, Jeon YC, Han DS

  • KMID: 2258786
  • Korean J Med.
  • 2008 Sep;75(3):337-342.
Idiopathic portal hypertension (IPH) is characterized by portal hypertension and splenomegaly without portal vein obstruction or significant liver disease. Although IPH may occasionally be accompanied by portal vein thrombosis (PVT)...
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Long-term therapeutic effects of partial splenic embolization on secondary hypersplenism

Lee JM, Chon CY, Han JY, Yoon KT, Moon CM, Ahn SH, Han KH, Lee JT, Moon YM

  • KMID: 2256409
  • Korean J Med.
  • 2007 May;72(5):470-479.
BACKGROUND: Liver cirrhosis causes secondary hypersplenism and thrombocytopenia is clinically troublesome. Splenectomy (SPL) was thought to be the curative management for correcting thrombocytopenia. However, decompensated liver function prevents any surgical...
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Successful Treatment with Partial Splenic Embolization in a Case of Post-transplantations Lymphoproliferative Disease with Persistent Hypersplenism

Kim MJ, Rho YI, Yang ES, Moon KR

  • KMID: 1979844
  • Korean J Pediatr Gastroenterol Nutr.
  • 2004 Mar;7(1):92-97.
Posttranplantations lymphoproliferative disease (PTLD) is a common and life-threatening complication for soid organ transplantation associated with the use of chronic immunosuppression and Epstein-Barr virus. There is no standardized treatment algorithm,...
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The Role of Splenectomy in Patients with Hepatocellular Carcinoma and Secondary Hypersplenism

Oh JW, Ahn SM, Kim KS, Choi JS, Lee WJ, Kim BR

Hypersplenism, secondary to portal hypertension, is common in hepatocellular carcinoma (HCC) with liver cirrhosis. Hepatic resection in the patient with hypersplenic thrombocytopenia (HSTC) may cause a perioperative bleeding episode and...
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Relationship between Thrombocytopenia and Serum Thromobopoietin Concentration in Patients with Chronic Liver Diseases

Cho YK, Kim BI, Koo ES, Kim SY, Kim CS, Park CY, Sohn CI, Jeon WK, Jung ES, Lee SH, Lee DH

  • KMID: 1606578
  • Korean J Gastroenterol.
  • 2002 Feb;39(2):108-113.
BACKGROUND/AIMS: The major origin of thrombocytopenia in liver cirrhosis is attributed to enlarged spleen. In order to determine the influence of thromboprotein (TPO) on the origin of thrombocytopenia in liver...
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Isolated Splenic Infarction in a Patient with Systemic Lupus Erythematosus

Suh JH, Park W, Park BH, Kim SS, Lee YH, Song JS, Choe WS

  • KMID: 2202409
  • J Korean Rheum Assoc.
  • 2002 Dec;9(4):304-307.
Systemic lupus erythematosus (SLE) is a multisystemic inflammatory autoimmune disease caused by various autoantibodies and immune complexes. Splenic involvement in SLE includes hypersplenism, splenic atrophy, and splenic infarction, which has...
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Clinical and Pathological Manifestations of Idiopathic Portal Hypertension

Lee JH, Kang DH, Lee CH, Song GA, Cho M, Yang US

  • KMID: 2241279
  • Korean J Hepatol.
  • 2000 Jun;6(2):187-196.
BACKGROUND/AIMS: Idiopathic portal hypertension (IPH) is defined as portal hypertension with splenomegaly and hypersplenism in the absence of cirrhosis or obstruction of portal vein or hepatic vein. It has been...
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Spontaneous Rupture of Spleen in a Patient with Malarial Infection

Park MH, Cha JG, Koo WH, Rho JH, Cho CK, Kim HJ

  • KMID: 2324916
  • J Korean Surg Soc.
  • 2000 Oct;59(4):562-566.
Malaria is a protozoan disease transmitted by the bite of infected mosquitoes. During acute and chronic malarial infection, altered splenic structure and function produce asymptomatic enlargement or com plications such as...
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Analysis of a Distal Splenorenal Shunt for Treatment of Variceal Bleeding

Lee YS, Kim WW, Jeon HM, Kim EK

  • KMID: 2209253
  • J Korean Surg Soc.
  • 2000 Jan;58(1):121-126.
BACKGROUND: Portal hypertension is a pathologic phenomenon caused by increased pressure in the portal vein. It's clinical importance lies in the development of secondary complications, such as variceal bleeding, hypersplenism,...
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The Significance of Serum Thrombopoietin Levels in Cirrhotic Patients with Thrombocytopenia According to Disease Severity

Yeon JE, Kong W, Kim JH, Suh YS, Park SH, Kwon OS, Byun KS, Lee CH

  • KMID: 2241312
  • Korean J Hepatol.
  • 1999 Sep;5(3):208-216.
BACKGROUND/AIMS: Thrombopoietin (TPO) is an important cytokine for megakaryocyte maturation and platelet production. Because the main site of its production is liver, the failing liver may have a role in thrombocytopenia in...
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A Case of Autoimmune Hemolytic Anemia Developed in Chronic Lobular Hepatitis B

Kang HS, Lee HY, Kim YS, Lee KS, Kim BI, Yie YC, Lee JH, Lee MR, Byun DI, Yoon MY, Lee SN

  • KMID: 2305233
  • Korean J Hematol.
  • 1998 Aug;33(2):256-261.
Although a pathogenic mechanism of hemolytic anemia complicated with viral hepatitis is unknown, it is suggested that there are four mechanisms; 1) In the individual who has predisposition to hemolytic...
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Effect of Splemegaly and Platelet Associated IgG on Thrombocytopenia in Patients with Chronic Liver Disease

Park BC, Han BH, Lim JH, Kim JH, Lee CH, Chung HG

  • KMID: 2240628
  • Korean J Gastroenterol.
  • 1998 Apr;31(4):512-516.
BACKGROUND AND AIMS: Thrombocytopenia is frequently found in patients with chronic liver disease. The mechanism of thrombocytopenia has been attributed to hypersplenism. Recently, several reports have shown that platelet associated...
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A Case of Secondary Hemosiderosis and Hepatic Fibrosis in a Pateint with Acute Myelogenous Leukemia

Kim HN, Huh JW, Park JS

  • KMID: 2207961
  • J Korean Pediatr Soc.
  • 1998 Mar;41(3):420-424.
Chronic iron overload is associated with life-threatening complications, such as cardiomyopathy, liver cirrhosis, diabetes, hypothyroidism, hypoparathyroidism and hypogonadism. We experienced a case of secondary hemosiderosis with hepatic fibrosis in a...
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A Case of Splenic Embolization Followed by Splenectomy with Preservation of Accessory Spleen in Gaucher's Disease

Ryu KS, Soh EY, Lim HY, Kim HJ, Kim MW

  • KMID: 2206423
  • J Korean Surg Soc.
  • 1998 Oct;55(4):598-603.
Gaucher's disease is an autosomal recessive genetic disorder of lipid metabolism. A deficiency of beta-glucocerebrosidase causes an accumulation of glucocerebroside in the reticulo-endothelial system and bone marrow. Total or partial...
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