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Impact of enhanced recovery after surgery program for hungry bone syndrome in patients on maintenance hemodialysis undergoing parathyroidectomy for secondary hyperparathyroidism

Wang L, Zhang X, Hu F, Yuan H, Gao Z, He L, Zou S

Purpose: Hungry bone syndrome after parathyroidectomy is an important clinical problem in patients on maintenance hemodialysis. We examined the effect of an enhanced recovery after surgery (ERAS) program on the...
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Update on Preoperative Parathyroid Localization in Primary Hyperparathyroidism

Park HS, Hong N, Jeong JJ, Yun M, Rhee Y

Parathyroidectomy is the treatment of choice for primary hyperparathyroidism when the clinical criteria are met. Although bilateral neck exploration is traditionally the standard method for surgery, minimally invasive parathyroidectomy (MIP),...
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Giant Parathyroid Adenomas: Differential Aspects Compared to Atypical Parathyroid Adenomas

McCoy K, Bakkila B, Gibson C

Primary hyperparathyroidism is a common diagnosis, often caused by a parathyroid adenoma, which can be resolved with surgical excision. However, pre-operative diagnosis of the causative adenoma may be challenging given...
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Supernumerary Ectopic Mediastinal Parathyroid Adenoma Combined With Parathyroid Hyperplasia

Gwak JW, Kim JH, Kim TG, Yu MS

Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by elevated parathyroid hormone levels. In most cases, the disease involves a single parathyroid adenoma, followed by parathyroid hyperplasia, but the...
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Retropharyngeal Ectopic Parathyroid Adenoma Localized by 18F-Fluorocholine Positron Emission Tomography/Computed Tomography: A Case Report

Jang H, Lee S, Kim D, Hong N

Ectopic parathyroid adenomas of the retropharyngeal space are relatively rare. Herein, we report a case of primary hyperparathyroidism (PHPT) secondary to a retropharyngeal parathyroid adenoma. A 22-year-old woman presented with...
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Analysis of the cause and management of persistent laboratory abnormalities occurring after the surgical treatment of primary hyperparathyroidism

Lee JE, Hong N, Kim JK, Lee CR, Kang SW, Jeong JJ, Nam KH, Chung WY, Rhee Y

Purpose: The surgical success rate for primary hyperparathyroidism (PHPT) is currently 95%–98%. However, 3%–24% of patients show persistently elevated (Pe) parathyroid hormone (PTH) levels after parathyroidectomy (PTX). This singlecenter retrospective...
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Parathyroidectomy versus cinacalcet in the treatment of tertiary hyperparathyroidism after kidney transplantation: a retrospective study

Jung S, Kim H, Kwon H, Shin S, Kim YH, Kim WW, Sung TY, Lee YM, Chung KW, Park SK, Baek CH

Background: Hyperparathyroidism is common in patients with chronic kidney disease with reduced renal function and has been observed after kidney transplantation. The optimal treatment for cases in which hyperparathyroidism persists...
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Three pediatric patients with primary hyperparathyroidism caused by parathyroid adenoma

Oh A, Lee Y, Yoo HW, Choi JH

Primary hyperparathyroidism (PHPT) is a hypercalcemia disorder with inappropriately normal or increased serum parathyroid hormone (PTH) levels resulting from excessive secretion of PTH from one or more of the parathyroid...
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Parathyroid Crisis as Presentation of Atypical Parathyroid Adenoma: Two Diagnostically Challenging Cases

Landeta GAS, Montes AT, Jimenéz TIG, Guadalupe VO, Baldomero GV, Lourdes BH

Atypical parathyroid adenoma (APA) is a rare cause of primary hyperparathyroidism (PHPT) and represents a diagnostic challenge since it is an intermediate form of parathyroid neoplasm of uncertain malignant potential...
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Role and Recent Trend of Intraoperative Parathyroid Hormone Monitoring During Parathyroidectomy in Patients With Primary Hyperparathyroidism

Ahn D, Kwak JH

In the last few decades, the standard surgical treatment for primary hyperparathyroidism (PHPT) has shifted from bilateral neck exploration to focused/minimally invasive parathyroidectomy (FMIP). This shift was accelerated by the...
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Efficacy and Safety of Ultrasound-Guided Radiofrequency Ablation for Primary Hyperparathyroidism: A Prospective Study

Chai Hh, Zhao Y, Zeng Z, Ye Rz, Hu Qh, He Hf, Baek JH, Peng Cz

Objective: To assess the efficacy and safety of ultrasound (US)-guided radiofrequency ablation (RFA) in patients with primary hyperparathyroidism (PHPT). Materials and Methods: This prospective study enrolled 39 participants (14 male, 25...
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Comparisons Between Normocalcemic Primary Hyperparathyroidism and Typical Primary Hyperparathyroidism

Choi HR, Choi SH, Hong N, Rhee Y, Kim JK, Lee CR, Kang SW, Lee J, Jeong JJ, Nam KH, Chung WY

Background: Normocalcemic primary hyperparathyroidism (NPHPT) was first described in 2008. It is defined as consistently elevated serum parathyroid hormone (PTH) levels with normal serum calcium (sCa) concentration, after excluding secondary...
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Hungry bone syndrome following parathyroidectomy for primary hyperparathyroidism in a developed country in the Asia Pacific. A cohort study

Chandran M, Bilezikian JP, Salleh NM, Ying H, Lau J, Lee J, deJong MC, Maung AC, Parameswaran R

Objectives We sought to assess the incidence of hungry bone syndrome (HBS) following parathyroidectomy (PTX) for primary hyperparathyroidism (PHPT) in a cohort of multi-ethnic patients from a developed country in the...
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Restless Legs Syndrome Resolving With Parathyroidectomy: A Case Report

Levine D, Adeboye A, Konstantinidis A

We present a case of restless legs syndrome (RLS) in a patient with primary hyperparathyroidism that was successfully managed with minimally invasive parathyroidectomy. RLS is a poorly understood movement disorder...
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Clinical features and signaling effects of RET D631Y variant multiple endocrine neoplasia type 2 (MEN2)

Lee Jy, Kim SY, Jo KH, Mo EY, Kim ES, Kim HS, Han JH, Moon Sd

Background/Aims: Germline mutations of the rearranged during transfection (RET) gene cause multiple endocrine neoplasia type 2 (MEN2). About 85% of RET mutations in MEN2 occur in codon Cys634. The RET...
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Effect of Human Umbilical Cord Matrix-Derived Mesenchymal Stem Cells on Bisphosphonate-Related Osteonecrosis of the Jaw

Yang G, Kim YN, Kim H, Lee BK

BACKGROUND: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a severe sequela caused by bisphosphonates (BPs), which are widely used to treat osteoporosis or other malignancies. However, the mechanism underlying BRONJ...
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Feasibility of Intraoperative Parathyroid Hormone Monitoring in Minimally Invasive Surgery

Kim SJ, Yun JH, Park S, Go YJ, Lee SJ, Jung SY, Kim HS

Background and Objectives There has been a long debate on whether intraoperative parathyroid hormone (IOPTH) monitoring is mandatory or not in the excision of a single abnormal parathyroid gland. The...
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Normocalcemic Primary Hyperparathyroidism: Need for a Standardized Clinical Approach

Zavatta G, Clarke BL

Since normocalcemic primary hyperparathyroidism (NHPT) was first defined at the Third International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism in 2008, many papers have been published describing its prevalence...
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A Case of Hyperparathyroidism Caused by Intrathyroidal Parathyroid Adenoma

Cho KJ, Park SW, Won S, Kim JP, Park JJ

Hyperparathyroidism is a common endocrine disorder, but intrathyroidal parathyroid adenoma is extremely rare. We report a on a case of hyperparathyroidism caused by intrathyroidal parathyroid adenoma. This case is important...
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Radioactive Parathyroid Adenomas on Sestamibi Scans: Low Parathyroid Hormone Secretory Potential and Large Volume

Kong SH, Kim JH, Kim SW, Shin CS

Background: We investigated the clinical characteristics of parathyroid adenomas according to radioactivity on 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) single-photon emission computed tomography/computed tomography (SPECT/CT) in primary hyperparathyroidism (PHPT) patients. Methods: The study included 217...
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