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Clinical association between serum cholesterol level and the size of xanthelasma palpebrarum

Kim YG, Oh JW, Lee KC, Yoon SH

Background: Xanthelasma palpebrarum (XP) is a benign periorbital lesion. The relationship between xanthelasma lesion size and serum cholesterol levels has been poorly studied. In this study, we investigated this relationship...
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Determinants of self‑reported hypertension among women in South Africa: evidence from the population‑based survey

Morton Ntenda P,  El‑Meidany W, Tiruneh F, Sebenele Motsa M, Nyirongo J, Chirwa G, Kapachika A, Nkoka O

Background: Hypertension (HTN), characterized by an elevation of blood pressure, is a serious public health chronic condition that significantly raises the risks of heart, brain, kidney, and other diseases. In...
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Metabolic risks in living kidney donors in South Korea

Kang E, Park J, Kim HJ, Park S, Park M, Kim Y, Kim K, Park SM, Chae DW, Chin HJ, Lee JP, Lee S, Kim SW, Cho JH, Han M, Kim YC, Kim YS, Choi I, Lee H

Background: Considering the growing prevalence of Western lifestyles and related chronic diseases occurring in South Korea, this study aimed to explore the progression of metabolic risk factors in living kidney...
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Role of Genetics in Preventive Cardiology: Focused on Dyslipidemia

Lee SH

Dyslipidemia is a strong risk factor for cardiovascular disease as well as a major target for its prevention. Along with the progress in genetic research techniques and bioinformatics analysis, genetic...
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Effects of cholesterol and Lactobacillus acidophilus on testicular function

Çiftci G, Tuna E

Objective: In this study, the effects of Lactobacillus acidophilus on testosterone (TES), follicle-stimulating hormone (FSH), luteinizing hormone (LH), androgen-binding protein (ABP), factor-associated apoptosis (FAS), and total cholesterol (TC), as well...
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Lipid Profiles in Primary Aldosteronism Compared with Essential Hypertension: Propensity-Score Matching Study

Moon SJ, Jang HN, Kim JH, Moon MK

Background: There has been controversy regarding the association between primary aldosteronism (PA) and dyslipidemia and few studies considered the effects of diabetes and renal function on lipid metabolism. We analyzed...
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Efficacy of nobiletin in improving hypercholesterolemia and nonalcoholic fatty liver disease in high-cholesterol diet-fed mice

Kim YJ, Yoon DS, Jung UJ

BACKGROUND/OBJECTIVES: Nobiletin (NOB), a citrus flavonoid, is reported to have beneficial effects on cardiovascular and metabolic health. However, there is limited research investigating the effect of long-term supplementation with low-dose...
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Dyslipidemia Fact Sheets in Korea 2020: an Analysis of Nationwide Population-based Data

Cho SMJ, Lee H, Lee HH, Baek J, Heo JE, Joo HJ, Hong SJ, Kim HC, on behalf of the Korean Society of Lipidology and Atherosclerosis (KSoLA) Public Relations Committee

Objective: The Korean Society of Lipid and Atherosclerosis (KSoLA) has published the Dyslipidemia Fact Sheets in Korea 2020 to provide an overview of magnitude and management status of dyslipidemia and...
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Maternal high-fructose intake during pregnancy and lactation induces metabolic syndrome in adult offspring

Koo S, Kim M, Cho HM, Kim I

BACKGROUND/OBJECTIVES: Nutritional status and food intake during pregnancy and lactation can affect fetal programming. In the current metabolic syndrome epidemic, highfructose diets have been strongly implicated. This study investigated the...
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Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status

Jung CH, Son JW, Kang S, Kim WJ, Kim HS, Kim HS, Seo M, Shin HJ, Lee SS, Jeong SJ, Cho Y, Han SJ, Jang HM, Rho M, Lee S, Koo M, Yoo B, Moon JW, Lee HY, Yun JS, Kim SY, Kim SR, Jeong IK, Mok JO, Yoon KH

Background: This study aimed to investigate the recent prevalence, management, and comorbidities of diabetes among Korean adults aged ≥30 years by analyzing nationally representative data. Methods: This study used data from...
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Trends in the prevalence and management of major metabolic risk factors for chronic disease over 20 years: findings from the 1998-2018 Korea National Health and Nutrition Examination Survey

Kim Y, Nho SJ, Woo G, Kim H, Park S, Kim Y, Park O, Oh K

OBJECTIVES: We aimed to explore trends in the prevalence and management of obesity, hypertension, diabetes, and hypercholesterolemia in Korean adults from 1998 to 2018 using data from the Korea National...
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Limitations of current screening methods for lipid disorders in Korean adolescents and a proposal for an effective detection method: a nationwide, cross-sectional study

Shin JH, Cheong JI, Cheuh HW, Yoo JH

Purpose: To determine the limitations of current screening methods for lipid disorders and to suggest a new method that is effective for use in Korean adolescents. Methods: Data from the 6th...
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Efficacy of Evolocumab in Patients with Hypercholesterolemia

Jin X, Kim MH, Cho YR, Park JS, Song K, Yuan SL

Objectives: The FOURIER trial reported that inhibition of PCSK9 with evolocumab on a background of statin therapy lowered low-density lipoprotein (LDL) cholesterol levels to a median of 30 mg per...
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Multiple Huge Tendinous Xanthomas with Normal Lipid Profiles in All Extremities

Seo DH, Roh SG, Shin JY, An MY, Kim JL, Chang SC, Lee NH

Xanthomas are grayish-yellow masses composed of lipid-filled foamy histiocytes and are usually accompanied by familial hypercholesterolemia or some other disease associated with dysfunctional lipid metabolism. Here, we report a case...
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Metabolic Health, Obesity, and the Risk of Developing Open-Angle Glaucoma: Metabolically Healthy Obese Patients versus Metabolically Unhealthy but Normal Weight Patients

Jung Y, Han K, Park HYL, Lee SH, Park CK

BackgroundThis study sought to investigate the associations between metabolic health status, obesity, and incidence of primary open-angle glaucoma (POAG).MethodsIn this nationwide, population-based, longitudinal prospective cohort study conducted using the Korean...
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Minimizing the risk of perioperative cardiovascular complications in homozygous familial hypercholesterolemia: a case report

Khan S, Min S, Willard G, Lo I, D'Souza R, Park A

Homozygous familial hypercholesterolemia (HoFH) is a rare inherited disorder that presents as abnormally elevated levels of low-density lipoprotein cholesterol and premature heart disease, requiring frequent intervention through lipid apheresis for...
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Factors Influencing Pre-Diabetes in Middle-aged Women based on the KNHANES

Kim KA, Shim JL

PURPOSE: This study was conducted to identify the predictive factors for pre-diabetes in middle-aged Korean women based on the Korean National Health and Nutrition Examination Survey (KNHANES). METHODS: In this cross-sectional...
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Characteristics of Acute Cerebral Infarction in Patients with Familial Hypercholesterolemia

Kim J, Park SH, Kim JM, Lee SH, Park KY

BACKGROUND: The patients with familial hypercholesterolemia (FH) suffer from early onset atherosclerotic vascular disease due to high level of cholesterol and subsequent vascular inflammation, especially in the form of coronary...
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Efficacy and safety of alirocumab in Korean patients with hypercholesterolemia and high cardiovascular risk: subanalysis of the ODYSSEY-KT study

Nam CW, Kim DS, Li J, Baccara-Dinet MT, Li I, Kim JH, Kim CJ

BACKGROUND/AIMS: Efficacy and safety data of alirocumab, a fully human monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9), is not yet well established in the Korean population. We assessed...
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Diabetes Fact Sheets in Korea, 2018: An Appraisal of Current Status

Kim BY, Won JC, Lee JH, Kim HS, Park JH, Ha KH, Won KC, Kim DJ, Park KS

BACKGROUND: The objective of this study was to investigate the prevalence, management, and comorbidities of diabetes among Korean adults aged 30 years and older. METHODS: This study used 2013 to 2016...
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