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The role of hydroxyl radical in the pathogenetic mechanism of endotoxin-induced acute lung injury in rats

Shim YS, Yoo CG, Kim YW, Han SK, Kim KY, Han YC

  • KMID: 1699811
  • Tuberc Respir Dis.
  • 1992 Apr;39(2):120-130.
No abstract available.
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The Effect of Hydroxyl Radical Generation on the Cytotoxicity of Alveolar Macrophage and Lipid Peroxidation of Erythrocyte Membrane by Mineral Fibers

Kim KA, Lim Y, Kim JH, Chang HS, Park CY, Yun IG, Oh MH

  • KMID: 1529780
  • Korean J Occup Environ Med.
  • 1997 Oct;9(3):401-410.
No abstract available.
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Brain Temperature Alters Hydroxyl Radical Production During Cerebral Ischemia/Reperfusion in Rats

Kil HY, Piantadosi CA

No abstract available.
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Effects of H2O2 Derived Hydroxyl Radicals Treated Fibronectin on Rat Calvarial Osteoblast

Shin SJ, Kang ES, Kim SJ

  • KMID: 2199173
  • J Korean Orthop Res Soc.
  • 1999 Apr;2(1):69-76.
Fibronectin is involved in various cellular activities such as adhesion, proliferation and migration as a substratum. Since the metabolic turnover of fibronectin is much slower than other cellular components, it...
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Hydroxyl radical-mediated commitment of HL-60 cells to differentiation: Modulation of differentiation process by phosphodiesterase inhibitors

Cho JY, Ahn WS, Cha SH, Lee KH, Kim WI, Chung MH

  • KMID: 1849845
  • Korean J Physiol Pharmacol.
  • 1998 Jun;2(3):369-376.
Ms report shows that hydroxyl radical, generated by a Fenton reaction involving adenosine 5'-diphosphate/Fe2+ complex (5-15 micrometer) and H2O2 (2 micrometer), induced differentiation of HL-60 cells in a dose- and time-dependent manner. This...
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Antioxidant and antidiabetic activities of extracts from Cirsium japonicum roots

Yin J, Heo SI, Wang MH

This study investigated the antioxidant activity of methanol (MeOH) and water extracts from roots of Cirsium japonicum in vitro. MeOH extract showed a stronger free radical scavenging activity than water...
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Experimental Studies of Hydroxyl Radical Generation in Reperfusion Injury after Cerebral Ischemia

Kim GH, Jun HK, Park YK, Jung HS, Lee KC, Chu JW, Lee HK

  • KMID: 1955075
  • J Korean Neurosurg Soc.
  • 1995 Oct;24(10):1103-1112.
The time course of hydroxyl radical generation in the brain and the intensity of brain hydroxyl radical(OH) generation were examined in rat during the first four hours after postischemia reperfusion....
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Effects of Nitric Oxide Synthase Inhibition on Hydroxyl Radical Production during Global Cerebral Ischemia/Reperfusion in Rats

Lim SY, Kim JS, Oh WS, Kim KM

BACKGROUND: Free radical-mediated oxidative damage has been implicated in ischemic brain injury. There are also increasing evidences that nitric oxide is involved in the mechanisms of cerebral ischemia. To elucidate...
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Role of Hydroxyl Radicals and Lipid Peroxidation in Cisplatin-induced Acute Renal Failure in Rabbits

Yang YS, Kwak IS, Nah HY, Kim YK

  • KMID: 1611201
  • Korean J Nephrol.
  • 2002 Mar;21(2):213-221.
PURPOSE: This study was undertaken to determine whether lipid peroxidation induced by hydroxyl radicals play a critical role in cisplatin(cis-diamminedichloroplatinum II)-induced acute renal failure. METHODS: Animals received cisplatin at a single...
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Effect of Dimethylsulfoxide on the Release of [3H]-5-hydroxytryptamine after Hypoxia from Rat Hippocampal Slices

Lee KE

OBJECTIVE: The present study was aimed to investigate the ability of free radical scavenger(hydroxyl radical scavenger, dimethyl sulfoxide, DMSO) to change the release of 5-hydroxytryptamine(5-HT)from the hypoxia-sensitive rat hippocampal slices. METHOD:...
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Antioxidant and Anti-inflammatory Activity of Six Halophytes in Korea

Lee JM, Yim MJ, Choi G, Lee MS, Park YG, Lee DS

The aim of this study was to measure and compare polyphenol content, antioxidant, and anti-inflammatory activity of six halophytes (Limonium tetragonum, Suaeda glauca, Suaeda japonica, Salicornia europaea, Triglochin maritimum, and...
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The Effect of Free Radical Scavengers on Reperfusion Injury after Testicular Torsion

Jung SY, Cho DH, Chun CS

  • KMID: 1913762
  • Korean J Urol.
  • 1996 Feb;37(2):121-125.
The free radicals generated during the ischemic/reperfusion period have been suggested as a possible cause for tissue damage in organs. This state was conducted to investigate protective effects of free...
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6'-O-Galloylpaeoniflorin Protects Human Keratinocytes Against Oxidative Stress-Induced Cell Damage

Yao CW, Piao MJ, Kim KC, Zheng J, Cha JW, Hyun JW

  • KMID: 2048305
  • Biomol Ther.
  • 2013 Sep;21(5):349-357.
6'-O-galloylpaeoniflorin (GPF) is a galloylated derivate of paeoniflorin and a key chemical constituent of the peony root, a perennial flowering plant that is widely used as an herbal medicine in...
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Ischemic preconditioning in the rat hippocampus increases antioxidant activities but does not affect the level of hydroxyl radicals during subsequent severe ischemia

Choi YS, Cho KO, Kim EJ, Sung KW, Kim SY

  • KMID: 756079
  • Exp Mol Med.
  • 2007 Aug;39(4):556-563.
Several studies have demonstrated that ischemic preconditioning increases superoxide dismutase activity, but it is unclear how ischemic preconditioning affects events downstream of hydrogen peroxide production during subsequent severe ischemia and...
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Antioxidant effects of serotonin and L-DOPA on oxidative damages of brain synaptosomes

Ham SS, Kim DH, Lee SH, Kim YS, Lee CS

  • KMID: 1554130
  • Korean J Physiol Pharmacol.
  • 1999 Apr;3(2):147-155.
Antioxidant effects of serotonin and L-DOPA on neuronal tissues were examined by studying the oxidative damages of brain synaptosomal components. The study further explored the mechanism by which they exert protective actions. Serotonin...
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Hydroxyl Radical Production after Intrastriatal Injection of Dopamine and the Effect of Growth Hormone on the Apoptosis of Striatal Neurons Injured by Hypoxia-ischemia in Newborn Rat Brain

Cho JJ, Yu J, Jee YH, Lee SB, Oh SY, Kim HG, Chang YP

  • KMID: 1568741
  • J Korean Soc Pediatr Endocrinol.
  • 2004 Dec;9(2):145-151.
PURPOSE:We investigated the production of oxygen hydroxyl radicals in the striatum of neonatal rat brain after intrastriatal injection of dopamine (DA) and the effect of growth hormone (GH) on the...
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Effect of Pyroligneous Liquor on Oxygen Radicals and Their Scavenger Enzymes in Liver of CD Rats

Cho WK, Choi JH

  • KMID: 2078406
  • Korean J Nutr.
  • 2007 Mar;40(2):111-117.
This study was designed to investigate the effects of pyroligneous liquor on oxygen radicals and their scavenger enzy-mes in the liver of Cri/Bgi CD rats (7 rats per group )....
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Effects of Advanced Glycation Endproducts (AGE) on Rat Glomerular Epithelial Cells (GEC): Roles of Reactive Oxygen Species (ROS)

Ha TS, Kim HS

  • KMID: 1610148
  • Korean J Nephrol.
  • 2003 May;22(3):285-293.
BACKGROUND: AGE-induced oxidative stress is implicated in the development and progression of diabetic nephropathy. AGE also affect the GEC to increase their permeability, therefore, we investigate the possibility that AGE...
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Cisplatin-induced Alterations of Na+-dependent Phosphate Uptake in Renal Epithelial Cells

Lee SJ, Kwon CH, Kim YK

  • KMID: 1512910
  • Korean J Physiol Pharmacol.
  • 2007 Apr;11(2):71-77.
Cisplatin treatment increases the excretion of inorganic phosphate in vivo. However, the mechanism by which cisplatin reduces phosphate uptake through renal proximal tubular cells has not yet been elucidated. We...
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Antioxidative effects of Kimchi under different fermentation stage on radical-induced oxidative stress

Kim BK, Choi JM, Kang SA, Park KY, Cho EJ

BACKGROUND/OBJECTIVES: Kimchi is a traditional Korean fermented vegetable containing several ingredients. We investigated the protective activity of methanol extract of kimchi under different fermentation stages against oxidative damage. MATERIALS/METHODS: Fresh kimchi...
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