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Effect of Testosterone Replacement Therapy on Bone Mineral Density in Patients with Klinefelter Syndrome

Jo DG, Lee HS, Joo YM, Seo JT

PURPOSE: Klinefelter syndrome (KS) is related to testicular insufficiency, which causes low testosterone levels in serum. Generally, sex hormone levels and bone mineral density (BMD) are lower in patients with...
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Effect of Combined Sex Hormone Replacement on Bone/Cartilage Turnover in a Murine Model of Osteoarthritis

Yang JH, Kim JH, Lim DS, Oh KJ

BACKGROUND: Estrogens act on estrogen receptors distributed in articular cartilages, synovial membrane, and ligaments, which are thought to be related with degenerative changes. Meanwhile, progesterone is known to have a...
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