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Gallbladder Sarcomatoid Carcinoma Diagnosed after Surgery

Cho YH, Cha SW, Cho YD, Lee MY, Chu CW, Hong SS, Jin SY

Sarcomatoid carcinoma is rarely diagnosed as gallbladder cancer. Its aggressive nature, due to the characteristics of both sarcoma and carcinoma, results in a poor prognosis. We report a case of...
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Pancreatoduodenectomy following neoadjuvant chemotherapy in duodenal adenocarcinoma

Seo D, Park BG, Jung D, Hwang HK, Kim SH, Hong SS, Kang CM

A 51-year-old male patient had four times of massive hematochezia episode three days before arrival. Carbohydrate antigen (CA) 19-9 level was extremely elevated. Computed tomography, magnetic resonance imaging, and positron...
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Radiologic Evaluation of Uterine Lesions Using a Pattern Recognition Approach

Lee NY, Lee EJ, Hong SS, Hwang J, Chang YW, Oh E, Nam B, Jeong J

It is important to distinguish uterine lesions from other lesions occurring in the pelvic cavity for the proper management. The primary radiological evaluation of uterine lesions is performed using transvaginal...
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An analysis of missed injuries in patients with severe trauma

Ju E, Baek SY, Hong SS, Kim Y, Youn SH

Purpose: To analyze the data of trauma patients with undetected injuries at the time of initial resuscitation during the primary and secondary surveys. Methods: We retrospectively reviewed the medical records of...
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Laparoscopic distal pancreatosplenectomy for left-sided pancreatic cancer in patients with radical subtotal gastrectomy for gastric cancer

Lee KH, Hong SS, Kim Ss, Hwang HK, Lee WJ, Kang CM

After radical subtotal gastrectomy (RSTG) for stomach cancer, the remnant stomach is supposed to be perfused through the short gastric vessels. What if a patient who received previous RSTG is...
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Heat Shock Protein 70 in Penile Neurovascular Regeneration Requires Cystathionine Gamma-Lyase

Ghatak K, Yin GN, Hong SS, Kang JH, Suh JK, Ryu JK

Purpose: Diabetes mellitus, one of the major causes of erectile dysfunction, leads to a poor response to phosphodiesterase-5 inhibitors. Heat shock protein 70 (Hsp70), a ubiquitous molecular chaperone, is known...
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COVID-19 in a Patient Previously Exposed to Toxic Disinfectant from a Humidifier

Youn SH, Hong SS, Baek SY, Kim Y

In August, 2011, the Korean Public Health Surveillance declared an outbreak of pulmonary disease due to the inhalation of humidifier disinfectants (HDs), which led to approximately 20,000 deaths. In March,...
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A Case Series of Trauma Resuscitation in the Intensive Care Unit Bypassing the Emergency Room During the Conversion to a COVID-19 Only Hospital

Youn SH, Kwon H, Baek SY, Hong SS, Kim Y

When a patient with severe trauma is admitted to the emergency room (ER), they are evaluated before transfer to either the intensive care unit (ICU) or operating room. To minimize...
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A Prognostic Impact of Splenectomy in Laparoscopic Distal Pancreatectomy on Benign/Borderline Pancreatic Tumors: A Change of the Era

Hong SS, Cha SW, Hwang HK, Lee WJ, Kang CM

Purpose: In the past, spleen preservation during distal pancreatectomy (DP) was preferred; however, more recent studies reported comparable results between splenectomy and spleen preserving. We retrospectively reviewed patients in a...
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Combination Therapy of the Active KRAS-Targeting Antibody inRas37 and a PI3K Inhibitor in Pancreatic Cancer

Lee JE, Woo MG, Jung KH, Kang YW, Shin SM, Son MK, Fang Z, Yan HH, Park JH, Yoon YC, Kim YS, Hong SS

KRAS activating mutations, which are present in more than 90% of pancreatic cancers, drive tumor dependency on the RAS/ mitogen-activated protein kinase (MAPK) and phosphoinositide 3-kinase (PI3K)/AKT signaling pathways. Therefore,...
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Primary Colonic Epithelioid Angiosarcoma with Hepatic Metastasis: A Case Report

Lim J, Hong SS, Hwang J, Kim Hj, Jin SY

Colonic angiosarcoma is an extremely rare and aggressive malignant tumor with poor prognosis. We report a case of colonic epithelioid angiosarcoma with colonic obstruction and rapidly progressive hepatic metastasis in...
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Adverse Impact of Intraoperative Conversion on the Postoperative Course Following Laparoscopic Pancreaticoduodenectomy

Connie LCK, Hong SS, Kang I, Rho SY, Hwang HK, Lee WJ, Kang CM

Purpose: The aim of the current study was to evaluate the adverse clinical impact of intraoperative conversion during laparoscopic pancreaticoduodenectomy (LPD). Materials and Methods: The medical records of patients who underwent...
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Reproducibility and diagnostic performance of the vascular index of superb microvascular imaging in real-time breast ultrasonography for evaluating breast masses

Lee EJ, Chang YW, Oh E, Hwang J, Kim Hj, Hong SS

Purpose: This study aimed to evaluate the reproducibility and diagnostic performance of a quantitative parameter of superb microvascular imaging (SMI) in real-time breast ultrasonography (US) for differentiating benign from malignant...
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Pharmacological Interventions on Surgical Intensive Care Units Initiated by Pharmacists

Lee J, Lee Ey, Yeo Yj, Oh Ys, Hong SS, Lee Jm

Purpose: The severity of a patient’s medical condition, changing pharmacodynamics and pharmacokinetics, and variability in medication highlight the importance of pharmacological intervention by intensive care unit (ICU) specialized pharmacists. Methods: Retrospective...
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Selonsertib Inhibits Liver Fibrosis via Downregulation of ASK1/ MAPK Pathway of Hepatic Stellate Cells

Yoon YC, Fang Z, Lee JE, Park JH, Ryu JK, Jung KH, Hong SS

Liver fibrosis constitutes a significant health problem worldwide due to its rapidly increasing prevalence and the absence of specific and effective treatments. Growing evidence suggests that apoptosis-signal regulating kinase 1...
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Disseminated Peritoneal Leiomyomatosis with Atypical Features and Comorbid Uterine STUMP: a Case Report and Review of the Literature

Ryu Kh, Lee EJ, Chang YW, Hong SS, Hwang Jy, Oh Es, Nam BD, Choi Ih, Lee HP

Disseminated peritoneal leiomyomatosis (DPL) is a very rare benign disease, characterized by multiple solid subperitoneal or peritoneal smooth muscle nodules in abdominopelvic cavity and malignant transformation is extremely rare. Also,...
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A Case Report of Tracheostomy for a Patient with COVID-19: How to Minimize Medical Staff and Patient Risks

Youn SH, Baek SY, Yoon J, Hong SS, Kim Y

Coronavirus disease was first reported in December 2019, and the World Health Organization declared it as a pandemic on March 11, 2020. The virus is known to attack various vital...
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PBT-6, a Novel PI3KC2γ Inhibitor in Rheumatoid Arthritis

Kim J, Jung KH, Yoo J, Park JH, Yan HH, Fang Z, Lim JH, Kwon SR, Kim MK, Park HJ, Hong SS

Phosphoinositide 3-kinase (PI3K) is considered as a promising therapeutic target for rheumatoid arthritis (RA) because of its involvement in inflammatory processes. However, limited studies have reported the involvement of PI3KC2γ...
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Comparison study for surgical outcomes of right versus left side hemihepatectomy to treat hilar cholangiocellular carcinoma

Hong SS, Han DH, Choi GH, Choi JS

PURPOSE: Major liver resection and radical lymph node dissection has been accepted as a definite treatment of choice for hilar cholangiocarcinoma (HC). However, the perioperative and survival outcomes of right...
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Primary Pelvic Peritoneal Yolk Sac Tumor in the Post-Pubertal Female: a Case Report with Literature Review

Kim M, Lee EJ, Hwang J, Hong SS, Chang YW, Oh E, Nam BD, Choi I, Kim JS

Yolk sac tumors are rare malignant germ cell neoplasms that usually arise from the gonads. Extragonadal yolk sac tumors (EGYSTs) frequently occur in the mediastinum in post-pubertal females. EGYSTs in...
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