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Association between Homocysteine Levels and Psoriasis: A Meta-Analysis

Kim JE, Lee HJ, Lee JS, Whang KU, Park YL, Lee SY, Kim HJ

BACKGROUND: Psoriasis is a multifactorial disease associated with an increased risk for metabolic syndrome and cardiovascular diseases. Elevated levels of homocysteine (Hcy) are a marker of cardiovascular risk. Several studies...
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Associations of Metabolic Syndrome with Total Testosterone and Homocysteine Levels in Male Korean Workers

Sung SH, Kim NH, Hong SP, Lee JK, Choi SJ

BACKGROUND: Low testosterone is associated with metabolic syndrome (MetS), and homocysteine (Hcy) is elevated in individuals with MetS. We investigated the relationships of total testosterone (TT) and serum Hcy levels...
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Short-Term and Long-Term Effects of Levetiracetam Monotherapy on Homocysteine Metabolism in Children with Epilepsy: A Prospective Study

Attilakos , Paschalidou M, Garoufi A, Tsirouda M, Papadopoulou A, Karalexi M, Dinopoulos A

BACKGROUND AND PURPOSE: Long-term treatment with some older antiepileptic drugs may lead to hyperhomocysteinemia. Levetiracetam (LEV) is a newer broad-spectrum antiepileptic agent whose effects on homocysteine concentrations remain unclear. The...
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Alexithymia, Suicide Ideation and Homocysteine Levels in Drug Naïve Patients with Major Depression: A Study in the “Real World” Clinical Practice

De Berardis D, Olivieri L, Rapini G, Di Natale , Serroni N, Fornaro M, Orsolini L, Valchera A, Carano A, Vellante F, Varasano P, Pressanti , Serafini G, Pompili M, Martinotti G, Di Giannantonio M

OBJECTIVE: This study was performed to elucidate relationships between alexithymia, suicide ideation and homocysteine levels in drug-naïve outpatients with major depressive disorder (MDD). METHODS: Sixty seven outpatients with MDD with melancholic...
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The Effect of Vitamin B12 and Folic Acid Supplementation on Serum Homocysteine, Anemia Status and Quality of Life of Patients with Multiple Sclerosis

Nozari E, Ghavamzadeh S, Razazian N

Plasma homocysteine level and megaloblastic anemia status are two factors that can affect the quality of life of patients with multiple sclerosis (MS). We conducted this study to determine the...
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Carotid Plaque Stiffness Measured with Supersonic Shear Imaging and Its Correlation with Serum Homocysteine Level in Ischemic Stroke Patients

Shang J, Wang W, Feng J, Luo GG, Dang Y, Sun J, Yang YQ, Ruan LT

OBJECTIVE: To ascertain the feasibility of using shear wave velocity (SWV) in assessing the stiffness of carotid plaque by supersonic shear imaging (SSI) and explore preliminary clinical value for such...
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The Effects of Korean DASH Diet Education Program on Oxidative Stress, Antioxidant Capacity, and Serum Homocysteine Level among Elderly Korean Women

Choi SH, Choi-Kwon , Kwak CS, Lee H

PURPOSE: The purpose of this study was to investigate the effects of the Korean Dietary Approaches to Stop Hypertension (DASH) education program on oxidative stress, antioxidant capacity, and serum homocysteine...
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Effects of folic acid supplementation on serum homocysteine levels, lipid profiles, and vascular parameters in post-menopausal Korean women with type 2 diabetes mellitus

Vijayakumar A, Kim EK, Kim H, Choi YJ, Huh KB, Chang N

BACKGROUND/OBJECTIVES: Complications of diabetes, such as cardiovascular disease, are associated with increased mortality among type 2 diabetes mellitus patients. Homocysteine has been recently identified as a predictor of cardiovascular disease-related...
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Effects of Homocysteine and Hyperglycemia on the Proliferation of Aortic Vascular Smooth Muscle Cells of Obese Type 2 Diabetes Rat

Yoo HJ, Yu SH, Cho YJ, Nam HW, Kang DH

BACKGROUND: The aim of this study was to investigate the role of homocysteine on the proliferation of rat aortic vascular smooth muscle cells (VSMCs) by measuring mitogen-activated protein (MAP) kinase...
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Association between Homocysteine and Bone Mineral Density according to Age and Sex in Healthy Adults

Kim JI, Moon JH, Chung HW, Kong MH, Kim HJ

BACKGROUND: There are several studies about the relationship between serum homocysteine levels and bone mineral density (BMD), but the results are varied, and the studies are limited in Korea. In...
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Sex Difference in the Association between Serum Homocysteine Level and Non-Alcoholic Fatty Liver Disease

Won BY, Park KC, Lee SH, Yun SH, Kim MJ, Park KS, Kim YS, Haam JH, Kim HY, Kim HJ, Park KH

BACKGROUND: The relationship between serum homocysteine levels and non-alcoholic fatty liver disease is poorly understood. This study aims to investigate the sex-specific relationship between serum homocysteine level and non-alcoholic fatty...
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Prognostic Value of Elevated Homocysteine Levels in Korean Patients with Coronary Artery Disease: A Propensity Score Matched Analysis

Kwon SW, Kim JY, Suh YJ, Lee DH, Yoon YW, Lee BK, Jung YH, Choi EY, Hong BK, Rim SJ, Kwon HM

BACKGROUND AND OBJECTIVES: We sought to determine whether an elevated homocysteine (Hcy) level is associated with a worse prognosis in Korean patients with coronary artery disease (CAD). SUBJECTS AND METHODS: A...
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Analysis of Serum Homocysteine and Risk of Coronary Heart Disease in Patients with Pseudoexfoliation Syndrome

Gu BY, Chu JH, Lim SH, Cha SC

PURPOSE: To investigate levels of serum homocysteine in patients with pseudoexfoliation syndrome and the association between serum homocysteine levels and risk of coronary heart disease. METHODS: From March 2013 to September...
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Combined effect of folate and adiposity on homocysteine in children at three years of age

Cho SJ, Lee HA, Park BH, Ha EH, Kim YJ, Park EA, Park H

BACKGROUND/OBJECTIVES: Cardiovascular diseases is a major cause of death and is responsible for 23.8% of deaths in Korea. Clinical symptoms manifest in adulthood, but susceptibility begins in utero. Elevated homocysteine...
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Two-year Follow-up Study of the Relationship between the Changes of Serum Homocysteine and Those of Serum Uric Acid Levels, Lipid Profiles and Renal Function in Gout Patients

Park EH, Park JH, Song JS, Choi ST

OBJECTIVE: Gout is known to be associated with cardiovascular disease (CVD), and hyperhomocysteinemia is one of the risk factors for CVD. We investigated the associations between the change of serum...
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Association of Homocysteine Levels with Subclinical Coronary Atherosclerosis in Asymptomatic Subjects

Nah EH, Cho HI, Choi JC

BACKGROUND: Progression of atherosclerotic plaques is known to be correlated with elevated circulating homocysteine (Hcy). However, whether the level of Hcy is related with coronary atherosclerosis in the subclinical state...
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Leukocyte Telomere Length is Associated With Serum Vitamin B12 and Homocysteine Levels in Older Adults With the Presence of Systemic Inflammation

Shin C, Baik I

Folate, vitamin B12, and homocysteine (HCY) are involved in the metabolism of nucleic acid precursors and it has been hypothesized that they also influence telomere length, a biomarker of aging....
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The Relationship between Uric Acid and Homocysteine Levels based on Alcohol-related Facial Flushing

Kim EC, Kim JS, Uh WC, Choi SY, Lee SK, Jeong BS

BACKGROUND: This study aimed to determine the correlation between blood uric acid and homocysteine levels, based on alcohol-related facial flushing. METHODS: Among male adults who visited a health examination center of...
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The Correlation of Levels of Serum Lipid, Homocysteine, and Folate with Volumes of Hippocampus, Amygdala, Corpus Callosum, and Thickness of Entorhinal Cortex in Patients with Amnestic Mild Cognitive Impairment or Dementia of Alzheimer's Type

Lee SJ, Kim TH, Huh L, Choi SE, Lee BJ, Kim GM, Lee JG, Kim HD, Mun CW, Kim YH

OBJECTIVES: In this study, the authors evaluated the correlation between levels of serum lipid, homocysteine, and folate with volumes of hippocampus, amygdala, corpus callosum, and in patients with amnestic mild...
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Poor nutrition and alcohol consumption are related to high serum homocysteine level at post-stroke

Choi SH, Choi-Kwon , Kim MS, Kim JS

BACKGROUND/OBJECTIVES: Increased serum homocysteine (Hcy) levels have been reported to be related to the occurrence of cardio- and cerebrovascular diseases. High serum Hcy levels are also related to the development...
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