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Chronic activation of CREB and p90RSK in human epileptic hippocampus

Park SA, Kim TS, Choi KS, Park HJ, Heo K, Lee BI

  • KMID: 1093608
  • Exp Mol Med.
  • 2003 Oct;35(5):365-370.
Mesial temporal lobe epilepsy (MTLE) is associated with severe neuronal death and reactive gliosis in hippocampus. However, the molecular mechanisms underlying these pathological changes remain unanswered. ERK has been reported...
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Differential changes in the expression of cyclic nucleotide phosphodiesterase isoforms in rat brains by chronic treatment with electroconvulsive shock

Cho CH, Cho DH, Seo MR, Juhnn YS

  • KMID: 755073
  • Exp Mol Med.
  • 2000 Sep;32(3):110-114.
Electroconvulsive shock (ECS) has been suggested to affect cAMP signaling pathways to exert therapeutic effects. ECS was recently reported to increase the expression of PDE4 isoforms in rat brain,...
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