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G protein signaling in the parasite Entamoeba histolytica

Bosch DE, Siderovski DP

  • KMID: 2154234
  • Exp Mol Med.
  • 2013 Mar;45(3):e15.
The parasite Entamoeba histolytica causes amebic colitis and systemic amebiasis. Among the known amebic factors contributing to pathogenesis are signaling pathways involving heterotrimeric and Ras superfamily G proteins. Here, we...
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Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells

Choi YJ, Kim SY, Oh JM, Juhnn YS

Stimulatory heterotrimeric GTP-binding proteins (Gs protein) stimulate cAMP generation in response to various signals, and modulate various cellular phenomena such as proliferation and apoptosis. This study aimed to investigate the...
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