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Hepcidin as a Biomarker of Cardiorenal Syndrome

Kim GH

No abstract available.
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Effect of Tocilizumab on Serum Hepcidin and Anemia Response in Patients with Rheumatoid Arthritis

Lee WS, Yoo WH

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Management of Anemia in Patients with Inflammatory Bowel Disease

Kim KO

Anemia is one of the commonest extraintestinal manifestations of inflammatory bowel disease (IBD). The pathogenesis of anemia in IBD is complex but iron deficiency combined with inflammation is the most...
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Increased Serum Hepcidin Levels in Children and Adolescents with Attention Deficit Hyperactivity Disorder

Yazici KU, Yazici IP, Ustundag B

OBJECTIVE: In this study, we aimed to evaluate the serum hepcidin levels in attention deficit hyperactivity disorder (ADHD) patients that were newly diagnosed with no history of psychotropic drugs. METHODS: A...
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Hepcidin and Neutrophil Gelatinase-Associated Lipocalin as a Biomarker for Acute Kidney Injury Linked Iron Metabolism

Cho SY, Hur M

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Differential regulation of hepcidin in cancer and non-cancer tissues and its clinical implications

Vela D, Vela-Gaxha Z

Hepcidin is a crucial peptide for regulating cellular iron efflux. Because iron is essential for cell survival, especially for highly active cells, such as tumor cells, it is imperative to...
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Clinical and Hematological Effects of Tocilizumab on Serum Hepcidin, Anemia Response and Disease Activity in Patients with Active Rheumatoid Arthritis

Park KJ, Jin HM, Cho YN, Kang JH, Jung HJ, Kang JH, Kim JE, Yim YR, Lee JW, Lee KE, Park DJ, Kim TJ, Lee SS, Kee SJ, Park YW

OBJECTIVE: The purpose of this study is to evaluate the clinical and hematological effects of tocilizumab in active rheumatoid arthritis (RA) patients. METHODS: Fourteen patients with active RA were enrolled in...
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Basic Understanding of Iron Metabolism

Suh JK, Jeon IS

Iron is critical for almost all living organisms because it serves as a cofactor for many proteins and enzymes necessary for oxygen and energy metabolism. Disruption of iron homeostasis is...
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New Oral Agent for Treatment of Anemia in Patient with Chronic Kidney Disease: Prolyl Hydroxylase Inhibitor

Na K

Hypoxia inducible factor (HIF)-stabilizers are being developed for the renal anemia treatment. This small molecules inhibit prolyl hydroxylase domain (PHD)-containing enzymes, causing HIF activation instead of degradation under the state...
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Regulation of Iron and Its Significance in Obesity and Complications

Chan YK, Sung HK, Sweeney G

Iron is an essential micronutrient with important roles in many critical physiological processes, especially as a structural component of hemoglobin responsible for oxygen transport. Iron homeostasis is tightly regulated, yet...
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Molecular Defense Mechanisms during Urinary Tract Infection

Choi SY, Chang IH

The urinary tract is a common site of infection. The complete mechanisms of urinary tract infection (UTI) are still unknown. In general, the strategies of the uropathogenic Escherichia coli are...
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Role of redox iron towards an increase in mortality among patients: a systemic review and meta-analysis

Sharma S

An increase in biochemical concentrations of non-transferrin bound iron (NTBI) within the patients with an increase in serum iron concentration was evaluated with the following objectives: (a) Iron overloading diseases/conditions...
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Relationship between Serum pro-hepcidin Concentration and Body Iron Status in Female College Students

Chung J

  • KMID: 2269909
  • Korean J Nutr.
  • 2005 Nov;38(9):750-755.
Hepcidin, a peptide hormone synthesized mainly by the liver, has been implicated as a key regulator of iron homeostasis. Results from studies with experimental animal models suggested that hepcidin levels...
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Hepcidin and iron parameters in children with anemia of chronic disease and iron deficiency anemia

Mahajan G, Sharma S, Chandra J, Nangia A

BACKGROUND: Anemia of chronic disease (ACD) and iron deficiency anemia (IDA) are the two most prevalent forms of anemia having interrelated characteristics. Hepcidin, a newly introduced biomarker for assessment of...
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Correlation between Pro-hepcidin Level and Iron Parameter in Infant Patients with Iron Deficiency Anemia and Anemia-free Infants

Ryu EY, Jang SH, Yeom JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Youn HS

  • KMID: 2279911
  • Clin Pediatr Hematol Oncol.
  • 2007 Oct;14(2):145-150.
PURPOSE: Anemia is one of the most common nutritional disorders in children, especially infants in their growing period. Hepcidin is known as an important regulator of iron metabolism, and reportedly...
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Treatment of renal anemia: Erythropoiesis stimulating agents and beyond

Biggar P, Kim GH

Anemia, complicating the course of chronic kidney disease, is a significant parameter, whether interpreted as subjective impairment or an objective prognostic marker. Renal anemia is predominantly due to relative erythropoietin...
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Effects of developmental iron deficiency and post-weaning iron repletion on the levels of iron transporter proteins in rats

Oh S, Shin PK, Chung J

BACKGROUND/OBJECTIVES: Iron deficiency in early life is associated with developmental problems, which may persist until later in life. The question of whether iron repletion after developmental iron deficiency could restore...
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Hepcidin Level and Iron Parameters in Patients with Chronic Kidney Disease

Seo JY, Song YH, Park MJ, Kim MJ, Seo YH, Ahn JY, Kim KH, Jeong JH, Chung W, Park PW

BACKGROUND: Hepcidin, a key regulator of iron homeostasis, is associated with iron metabolism imbalance in patients with chronic kidney disease (CKD). However, serum hepcidin level in anemic patients with CKD...
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Relationship between Cardiac Geometry and Serum Hepcidin in Chronic Kidney Disease: Analysis from the KNOW-CKD Study

Min HK, Oh YK, Choi KH, Lee KB, Park SK, Ahn C, Lee SW

BACKGROUND: Few studies have examined the relationship between cardiac function and geometry and serum hepcidin levels in patients with chronic kidney disease (CKD). We aimed to identify the relationship between...
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Can Calprotectin Show Subclinical Inflammation in Familial Mediterranean Fever Patients?

Asan G, Derin ME, DoÄŸan HO, Bayram M, Åžahin M, Åžahin A

BACKGROUND: Familial Mediterranean fever (FMF) is an autoinflammatory disease that has self-limiting inflammatory attacks during polyserositis. Hepcidin is a protein, and interleukin-6 stimulation increases hepcidin levels. Calprotectin (CLP) is a...
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