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Membranoproliferative glomerulonephritis associated with HCV infection in native kidneys and renal allograft

Jeong HJ, Choi KH, Chon CY, Kim SI, Park K

Hepatitis C viral infection occurs relatively low in Korea compared to hepatitis B. However, it progresses into chronic hepatitis and cirrhosis more frequently than HBV. It may be associated...
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Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a edictive factor for response to interferon-alpha therapy and development of patocellular carcinoma

Bae SH, Park YM, Yoo DG, Choi JY, Byun BH, Yang JM, Lee CD, Cha SB, Park DH, KiM BS

Genetic changes between codons 2209 and 2248 of NS5A of genotype 1b hepatitis C virus (HCV-1b) have been reported to be associated with the sensitivity to interferon-alpha (IFN-alpha). The present...
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Monitoring antibody titers to recombinant Core-NS3 fusion polypeptide is useful for evaluating hepatitis C virus infection and responses to interferon-alpha therapy

Park YM, Byun BH, Choi JY, Bae SH, Kim BS, So HS, Ryu WS

To evaluate the clinical feasibility of the antibody titer against a chimeric polypeptide (named Core 518), in which a domain of Core and NS3 of hepatitis C virus (HCV) was...
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Expression of Transforming Growth Factor beta-1 in Chronic Hepatitis and Hepatocellular Carcinoma Associated with Hepatitis C Virus Infection

Kim HG, Chung YH, Song BC, Kim JA, Yang SH, Lee YS, Suh DJ

  • KMID: 759514
  • Korean J Intern Med.
  • 2000 Dec;15(3):165-170.
BACKGROUND: Transforming growth factor beta-1 (TGF beta 1) has been suggested to play a role in the development, growth or progression of hepatocellular carcinoma (HCC). Genotype and serum titer of...
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The relationship between virological characteristics of hepatitis C virus (HCV) and reactivity to the regional specific proteins of HCV

Yoon SK, Park YM, Byun BH, Bae SH, Yang JM, Ahn BM, Lee YS, Lee CD, Sun HS, Kim BS

  • KMID: 759502
  • Korean J Intern Med.
  • 2000 Jul;15(2):109-116.
BACKGROUND: Although the polyproteins of hepatitis C virus(HCV) are processed and formed in nearly equimolar amounts, individual functional proteins have a discrepancy...
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Factors associated with positive predictability of the anti-HCV ELISA method with confirmatory RT-PCR

Kim YS, Lee HS, Ahn YO

The positive predictability of anti-HCV ELISA is low, especially, in blood donors and in healthy populations. False positive anti-HCV results pose some difficulties in medical practice and in blood screening....
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Hepatitis G virus infection in hemodialysis and continuous ambulatory peritoneal dialysis patients

Noh H, Kang SW, Choi SH, Shin SK, Seo BJ, Lee IH, Choi KH, Han DS, Kim HS, Lee HY

To determine the prevalence and clinical relevance of HGV infection in dialysis patients, we performed a cross-sectional study of 61 HD patients and 79 Continuous Ambulatory Peritoneal Dialysis (CAPD) patients....
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Experience of orthotopic liver transplantation in 11 patients with liver cirrhosis from Korea: medical factors affecting outcome

Choi JY, Park YM, Byun BH, Kim TY, Yoon SK, Chung KW, Sun HS, Park DH, Kim BS, Kim DG, Kim IC

Orthotopic liver transplantation (OLT) has evolved to become a standard treatment of choice for end-stage liver diseases. The present study was performed to evaluate the peri-operative medical factors affecting ...
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The prediction of interferon-alpha therapeutic effect by sequence variation of the HCV hypervariable region 1

Yeh BI, Kim HW, Kim HS, Lee JY, Lee KH, Lee KM, Kim JS, Han KH

Interferon-alpha (IFN-alpha) has been used to treat hepatitis C virus (HCV)-induced hepatitis, but it has been effective in only about half of the treated patients, with recurrence appearing in the...
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Hepatitis C virus genotypes in Korea and their relationship to clinical outcome in type C chronic liver diseases

Han CJ, Lee HS, Kim HS, Choe JH, Kim CY

  • KMID: 1038875
  • Korean J Intern Med.
  • 1997 Jan;12(1):21-27.
OBJECTIVES: The relationship between HCV genotype and the development of more serious liver disease has not been clearly established. This study was to investigate the distribution pattern of HCV genotypes...
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Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver

Park CK, Park TR, Kim YB, Kim HY, Yoo JY, Kim CH, Choo SH, Cho JM

  • KMID: 1038874
  • Korean J Intern Med.
  • 1997 Jan;12(1):28-33.
OBJECTIVES: Numerous epidemiologic data have documented that chronic infection by hepatitis C virus (HCV) is a major risk factor for the development of hepatocellular carcinoma (HCC). But the molecular mechanism...
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